Nietzschean criticism refocusing to democracy from the ecological reformulation of the political

La tesis de este trabajo es que la consideración de lo político desde la perspectiva ecológica, podría matizar la crítica nietzscheana a la democracia, hasta el punto de hacernos percibir una íntima cercanía entre la filosofía profunda de Nietzsche y la democracia, entendida esta como una forma política constituida en el juego del devenir, propio del tejido viviente. Desde su reformulación ecológica, la política democrática no sólo no estaría en contradicción con las ideas políticas del “aristocrático” pensador del devenir sino, al contrario, justamente ella podría ser el medio para lograr la elevación nietzscheana de la vida, y viceversa, la lucha por la realización de ordenes políticos democráticos y de una política que valore la riqueza y la fragilidad de la vida en la Tierra, parece requerir, más que nunca, profundizar su crítica a la democracia y atender a su llamado a recuperar el carácter creador de la políticaThe thesis of this paper is that the consideration of the political from the ecological perspective, could qualify the Nietzschean critique of democracy, to the point of making us perceive an intimate closeness between Nietzsche’s philosophy and democracy understood as a constituted political form In the game of becoming, proper to living tissue. Since its ecological reformulation, Democratic politics would not only not be in contradiction with the political ideas of the “aristocratic” thinker of becoming, but, on the contrary It could be the means to achieve the Nietzschean elevation of life, and vice versa, the struggle for the realization of democratic political orders and a policy that values the richness and fragility of life on Earth seems to require, more than never, deepen its critique of democracy and attend to its call to recover the creative nature of politic

Electrokinetic separation of non-steroidal antiinflamatory drugs by using graphene nanoparticles as pseudostationary phase

III Encuentro sobre Nanociencia y Nanotecnología de Investigadores y Tecnólogos Andaluce

Functional characterization of two enhancers located downstream FOXP2

Background: Mutations in the coding region of FOXP2 are known to cause speech and language impairment. However, it is not clear how dysregulation of the gene contributes to language deficit. Interestingly, microdeletions of the region downstream the gene have been associated with cognitive deficits. Methods: Here, we investigate changes in FOXP2 expression in the SK-N-MC neuroblastoma human cell line after deletion by CRISPR-Cas9 of two enhancers located downstream of the gene. Results: Deletion of any of these two functional enhancers downregulates FOXP2, but also upregulates the closest 3′ gene MDFIC. Because this effect is not statistically significant in a HEK 293 cell line, derived from the human kidney, both enhancers might confer a tissue specific regulation to both genes. We have also found that the deletion of any of these enhancers downregulates six well-known FOXP2 target genes in the SK-N-MC cell line. Conclusions: We expect these findings contribute to a deeper understanding of how FOXP2 and MDFIC are regulated to pace neuronal development supporting cognition, speech and language.Spanish National Research and Development Plan PI14/01884Instituto de Salud Carlos III PI14/01884FEDER PI14/0188

The ecology of resilience learning in ubiquitous environments to adverse situations

Primary education in Mexico is facing a growing set of challenges that the government has tried to counteract through the use of communication technologies (ICT) in formal education. While these efforts provide support for students and educators, there remains a need for a renewed and contextualized awareness that will re-conceptualize the adverse experiences of students and the importance of resilience in the context of the learning environment. The objective of this document is to give an account of the learning acquired by nine telesecondary students in a rural area of Hidalgo and the student’s benefits of building awareness about the ecology of learning. The paper highlights the process of re-envisioning their experiences that emerged from the various points of views shared in discussion. The study was triangulated by quantitative and qualitative phenomenological and hermeneutical analyses. It was organized into three stages and employed a survey, semi-structured interviews, focus groups and use of the Google-Classroom platform. The hermeneutical analysis of autobiographies and the use of technological resources enhanced the personal analysis of the experiences of the participants. These experiences generated learning that may often be invisible in formal education but can empower critical thinking, collaboration and autonomy of students to become aware of their learning and the scope of their social contribution

The ecology of resilience learning in ubiquitous environments to adverse situations

Primary education in Mexico is facing a growing set of challenges that the government has tried to counteract through the use of communication technologies (ICT) in formal education. While these efforts provide support for students and educators, there remains a need for a renewed and contextualized awareness that will re-conceptualize the adverse experiences of students and the importance of resilience in the context of the learning environment. The objective of this document is to give an account of the learning acquired by nine telesecondary students in a rural area of Hidalgo and the student’s benefits of building awareness about the ecology of learning. The paper highlights the process of re-envisioning their experiences that emerged from the various points of views shared in discussion. The study was triangulated by quantitative and qualitative phenomenological and hermeneutical analyses. It was organized into three stages and employed a survey, semi-structured interviews, focus groups and use of the Google-Classroom platform. The hermeneutical analysis of autobiographies and the use of technological resources enhanced the personal analysis of the experiences of the participants. These experiences generated learning that may often be invisible in formal education but can empower critical thinking, collaboration and autonomy of students to become aware of their learning and the scope of their social contribution

A simple formula to find the closest consistent matrix to a reciprocal matrix

Achieving consistency in pair-wise comparisons between decision elements given by experts or stakeholders is of paramount importance in decision-making based on the AHP methodology. Several alternatives to improve consistency have been proposed in the literature. The linearization method (Benitez et al., 2011 [10]), derives a consistent matrix based on an original matrix of comparisons through a suitable orthogonal projection expressed in terms of a Fourier-like expansion. We propose a formula that provides in a very simple manner the consistent matrix closest to a reciprocal (inconsistent) matrix. In addition, this formula is computationally efficient since it only uses sums to perform the calculations. A corollary of the main result shows that the normalized vector of the vector, whose components are the geometric means of the rows of a comparison matrix, gives the priority vector only for consistent matrices. (C) 2014 Elsevier Inc. All rights reserved.This work has been performed with the support of the project IDAWAS, DPI2009-11591 of the Direccion General de Investigacion del Ministerio de Ciencia e Innovacion (Spain), with the supplementary support of ACOMP/2010/146 of the Conselleria d'Educacio of the Generalitat Valenciana, and the support given to the first author by the Spanish project MTM2010-18539. The use of English in this paper was revised by John Rawlins; and the revision was funded by the Universitat Politecnica de Valencia, Spain.Benítez López, J.; Izquierdo Sebastián, J.; Pérez García, R.; Ramos Martínez, E. (2014). A simple formula to find the closest consistent matrix to a reciprocal matrix. Applied Mathematical Modelling. 38(15-16):3968-3974. https://doi.org/10.1016/j.apm.2014.01.007S396839743815-1