Análisis de los riesgos que causan la fuga de información en la empresa asesorías contables y revisoría fiscal JAA SAS

Software inteligente y convergencia tecnológicaAnálisis de los riesgos que generan fuga de información en una compañía de auditorias contables y revisoría fiscal, que va desde el levantamiento de información, la identificación de los activos, las entrevistas y encuestas realizadas, la identificación de políticas y documentos existentes, hasta la valoración de los riesgos y la sugerencias de controles para mitigarlos y así disminuir el riesgo de fuga de información.INTRODUCCIÓN 1. GENERALIDADES DEL TRABAJO DE GRADO 2. MARCOS DE REFERENCIA 3. METODOLOGÍA 4. DESARROLLO 5. CONCLUSIONES Y RECOMENDACIONES BIBLIOGRAFÍAEspecializaciónEspecialista en Seguridad de la Informació

The policy of transfer of curricular reforms between Spain and Brazil. Towards the psychologization of education

In order to adapt the organization and functioning of the educational system to the constitutional requirements derived from the document of 1978, the Spanish educational reform of the 1980s and 90s went beyond the national borders encompassing international spaces. In its broad and firm expansion to different countries of the Latin American orbit, we want to show how it had a special impact on the reform of the Brazilian education agreed in the nineties reflecting on its development, especially, in the PCNs (National Curricular Parameters). We approach this analysis, derived from the application of the Systematic Literature Review method, which we anticipate of high value and interest, from a threefold dimension that seeks to investigate the influences of Spanish educational policies on Brazil. Firstly, we make use of the essential and classic contribution on school culture made by Professor Escolano (2000). Secondly, we advance until we approach curriculum design (what we understand as“the discourse”) and its consequent projection. And finally, thirdly, we analyze the tensions between psychologists and pedagogues both in interpretative and academic terms that were illustrated in conferences, congresses, seminars and, of course, in the publication of books, articles and reports. Key words: educational system; psychological and pedagogical reform; influences of educational policies; Spain; Brazil

Using 3D Spectroscopy to Probe the Orbital Structure of Composite Bulges

Detailed imaging and spectroscopic analysis of the centers of nearby S0 and spiral galaxies shows the existence of "composite bulges", where both classical bulges and disky pseudobulges coexist in the same galaxy. As part of a search for supermassive black holes in nearby galaxy nuclei, we obtained VLT-SINFONI observations in adaptive-optics mode of several of these galaxies. Schwarzschild dynamical modeling enables us to disentangle the stellar orbital structure of the different central components, and to distinguish the differing contributions of kinematically hot (classical bulge) and kinematically cool (pseudobulge) components in the same galaxy.Comment: LaTeX, 2 pages, 1 PDF figure. To appear in "Proceedings of IAU Symposium 309: Galaxies in 3D across the Universe", eds. B. L. Ziegler, F. Combes, H. Dannerbauer, and M. Verdug

The Influence of Patient Experience with Healthcare on the Health-Related Quality of Life of People Living with HIV: An Observational Cross-Sectional Survey

[Abstract] Introduction Patient experience is central to the quality of healthcare delivery, showing positive associations with several outcome measures. The main objectives of this study are to analyze the influence of patient experience on the health-related quality of life in people living with HIV and the role played by treatment complexity and clinical care. Methods We conducted a cross-sectional survey with 467 patients with HIV. We used the Instrument for Evaluation of the Experience of Chronic Patients and the Health-related Quality of Life Questionnaire (EQ-5D-5L). We analyzed a predictive model through the partial least squares (PLS) method. Results The patient self-management scores showed the highest positive relationship with the patient’s health-related quality of life (β = 0.24, β = 0.32, p  50 years old (p < 0.05). Conclusions Patient experience mainly influenced the health-related quality of life of older people living with HIV. The treatment and clinical care complexity played an important role in degrading the patients' experience and their quality of life. More integrated care would benefit the health-related quality of life of people living with HIV

Proof-of-Concept Studies Directed toward the Formation of Metallic Ag Nanostructures from Ag3PO4 Induced by Electron Beam and Femtosecond Laser

In this work, for the first time, the instantaneous nucleation and growth processes of Ag nanoparticles on Ag3PO4 mediated by femtosecond laser pulses are reported and analyzed. The investigated samples are pure Ag3PO4sample, electron-irradiated Ag3PO4 sample, and laser-irradiated sample. Complete characterization of the samples is performed using X-ray diffraction (XRD), Rietveld refinements, field emission scanning electron microscopy, and energy dispersive spectroscopy (EDS). XRD confirms that the irradiated surface layer remains crystalline, and according to EDS analysis, the surface particles are composed primarily of Ag nanoparticles. This method not only offers a one-step route to synthesize Ag nanoparticles using laser-assisted irradiation with particle size control, but also reports a complex process involving the formation and subsequent growth of Ag nanoparticles through an unexpected additive-free in situ fabrication process

Los Retos Políticos y Sociopedagógicos de la Buena Educación en Castilla y León, España1

El presente trabajo de investigación versa sobre las relaciones “paradójicas” entre territorio y educación en España, tomando como referente el espacio castellanoleonés que ofrece, en base a informes nacionales e internacionales, unas cotas educativas plenamente comparables internacionalmente. Esta “buena educación” presenta un importante margen de mejora. El equipo de investigación ha realizado 59 entrevistas abiertas (a una muestra de 8 centros). Se han entrevistado dos tipos de actores: sociales y educativos. El estudio se estructura en dos partes. Una “política” en la que los retos se han diagnosticado a partir del enfoque metodológico SLR (Sistematic Literature Review) y, una segunda, “pedagógica”, en la que el tratamiento de las fuentes orales se ha realizado a partir del CCS (Comparative Case Study) (Bartlett y Vavrus). Los resultados nos indican que en el imaginario de los actores aparecen desafíos que requieren respuesta (política y social). Se refieren a las condiciones laborales y formativas de los docentes, a los recursos y medios, a las relaciones entre actores y a los ajustes curriculares. También exigen reforzar las relaciones con el entorno (socioeconómico e institucional), la estabilidad de las políticas educativas, la confianza y responsabilidad de y en la educación, un refuerzo de la autonomía escolar y pedagógica y la mejora de la formación de los equipos directivos.JCYL - Ref. SA017G19. Programa de apoyo a Grupos de Investigación Reconocidos de las universidades públicas de Castilla y León (BOCYL, 9/julio/2019)

Evaluación de pensamiento crítico: recuento de una experiencia interuniversitaria

El desarrollo y promoción del pensamiento crítico resulta de gran importancia para las instituciones de educación superior, dado el valor que tienen para la vida académica y profesional de los estudiantes. Para explorar la posibilidad de contar con pruebas de desempeño que evalúen el pensamiento crítico, un grupo de siete universidades colombianas adaptó y aplicó una de estas pruebas a una muestra de 356 estudiantes. Este artículo tiene como objetivo hacer un recuento del proceso de adaptación, pilotaje y aplicación final de la prueba

Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs

IntroductionThis study evaluated the immune response to a multiepitope recombinant chimeric protein (CHIVAX) containing B- and T-cell epitopes of the SARS-CoV-2 spike’s receptor binding domain (RBD) in a translational porcine model for pre-clinical studies.MethodsWe generated a multiepitope recombinant protein engineered to include six coding conserved epitopes from the RBD domain of the SARS-CoV-2 S protein. Pigs were divided into groups and immunized with different doses of the protein, with serum samples collected over time to determine antibody responses by indirect ELISA and antibody titration. Peptide recognition was also analyzed by Western blotting. A surrogate neutralization assay with recombinant ACE2 and RBDs was performed. Intranasal doses of the immunogen were also prepared and tested on Vietnamese minipigs.ResultsWhen the immunogen was administered subcutaneously, it induced specific IgG antibodies in pigs, and higher doses correlated with higher antibody levels. Antibodies from immunized pigs recognized individual peptides in the multiepitope vaccine and inhibited RBD-ACE2 binding for five variants of concern (VOC). Comparative antigen delivery methods showed that both, subcutaneous and combined subcutaneous/intranasal approaches, induced specific IgG and IgA antibodies, with the subcutaneous approach having superior neutralizing activity. CHIVAX elicited systemic immunity, evidenced by specific IgG antibodies in the serum, and local mucosal immunity, indicated by IgA antibodies in saliva, nasal, and bronchoalveolar lavage secretions. Importantly, these antibodies demonstrated neutralizing activity against SARS-CoV-2 in vitro.DiscussionThe elicited antibodies recognized individual epitopes on the chimeric protein and demonstrated the capacity to block RBD-ACE2 binding of the ancestral SARS-CoV-2 strain and four VOCs. The findings provide proof of concept for using multiepitope recombinant antigens and a combined immunization protocol to induce a neutralizing immune response against SARS-CoV-2 in the pig translational model for preclinical studies

Associated factors for mortality in a COVID-19 colombian cohort : is the third wave relevant when Mu variant was predominant epidemiologically?

Q1Q1Pacientes con COVID-19Objectives: To evaluate the association between Colombia's third wave when the Mu variant was predominant epidemiologically (until 75%) in Colombia and COVID-19 all-cause in-hospital mortality. Methods: In this retrospective cohort, we included hospitalized patients ≥18 years with SARS-CoV-2 infection between March 2020 to September 2021 in ten hospitals from three cities in Colombia. Description analysis, survival, and multivariate Cox regression analyses were performed to evaluate the association between the third epidemic wave and in-hospital mortality. Results: A total of 25,371 patients were included. The age-stratified time-to-mortality curves showed differences according to epidemic waves in patients ≥75 years (log-rank test p = 0.012). In the multivariate Cox analysis, the third wave was not associated with increased mortality relative to the first wave (aHR 0.95; 95%CI 0.84–1.08), but there was an interaction between age ≥75 years and the third wave finding a lower HR for mortality (aHR 0.56, 95%CI 0.36–0.86). Conclusions: We did not find an increase in in-hospital mortality during the third epidemic wave in which the Mu variant was predominant in Colombia. The reduced hazard in mortality in patients ≥75 years hospitalized in the third wave could be explained by the high coverage of SARS-CoV-2 vaccination in this population and patients with underlying conditions.https://orcid.org/0000-0003-1833-1599https://orcid.org/0000-0001-5363-5729https://orcid.org/0000-0001-6964-2229https://orcid.org/0000-0003-3975-2835https://orcid.org/0000-0001-9441-4375Revista Internacional - IndexadaA1N