Percepções de uma ingressante da licenciatura durante experiência Pibid interdisciplinar

Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014O trabalho do professor em sala de aula é carregado de complexidade, e é nesse sentido que o PIBID assume sua primordial importância, uma vez que permite ao acadêmico uma experiência ímpar no processo de sua formação profissional, que é a iniciação à docência, desde o adentrar a universidade. O objetivo deste trabalho é apresentar um projeto interdisciplinar desenvolvido numa turma de 5o ano, bem como as percepções de uma ingressante da licenciatur

Hjärtstillestånd: Sjukskötarens erfarenheter av omvårdnadssituationen

Bakgrund: Vid hjärtstillestånd som sker inom sjukhusmiljö är det oftast sjukskötaren som är först på plats. Sjukskötare är ofta de första som måste ta initiativ och påbörja återupplivningsförsök, kalla på hjälp och se till att patienten får den akuta hjälp som den behöver. Syfte: Syftet är att beskriva sjukskötarens erfarenheter av omvårdnadssituationen vid hjärtstillestånd. Metod: Detta arbete är en kvalitativ litteraturöversikt med ett induktivt förhållningssätt. Resultat: Litteraturöversiktens åtta artiklar resulterade i ett övergripande tema det är på liv och död samt tre underteman känslan av att kämpa tillsammans, utmaningen med att finnas för närstående samt kampen mellan rätt och fel. Slutsats: Sjukskötaren kan komma i kontakt med många olika utmaningar under ett hjärtstillestånd och de får ta ett stort ansvar gällande patientens liv. När sjukskötare har den kompetens och färdigheter som krävs kan de känna sig mer förberedda för ett hjärtstillestånd. När en patient pendlar mellan liv och död är det många olika faktorer som påverkar arbetet och överlevnadschansen för patienten

Decolonizing History: Enquiry and Practice

On the back of the Royal Historical Society’s 2018 report on race and ethnicity, as well as ongoing discussions about ‘decolonizing the syllabus’, this is a conversation piece titled, ‘Decolonizing History: Enquiry and Practice’. While ‘decolonization’ has been a key framework for historical research, it has assumed increasingly varied and nebulous meanings in teaching, where calls for ‘decolonizing’ are largely divorced from the actual end of empire. How does ‘decolonizing history’ relate to the study of decolonization? And can history, as a field of practice and study, be ‘decolonized’ without directly taking up histories of empire? Using the RHS report as a starting point, this conversation explores how we ‘decolonize history’. We argue that, rather than occurring through tokenism or the barest diversification of reading lists and course themes, decolonizing history requires rigorous critical study of empire, power and political contestation, alongside close reflection on constructed categories of social difference. Bringing together scholars from several UK universities whose teaching and research ranges across modern historical fields, this piece emphasizes how the study of empire and decolonization can bring a necessary global perspective to what tend to be framed as domestic debates on race, ethnicity, and gender

Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs

MicroRNAs (miRNAs) are 19–22-nucleotide noncoding RNAs that post-transcriptionally regulate mRNA targets. We have identified endogenous miRNA binding sites in mouse embryonic stem cells (mESCs), by performing photo-cross-linking immunoprecipitation using antibodies to Argonaute (Ago2) followed by deep sequencing of RNAs (CLIP-seq). We also performed CLIP-seq in Dicer[superscript −/−] mESCs that lack mature miRNAs, allowing us to define whether the association of Ago2 with the identified sites was miRNA dependent. A significantly enriched motif, GCACUU, was identified only in wild-type mESCs in 3′ untranslated and coding regions. This motif matches the seed of a miRNA family that constitutes ~68% of the mESC miRNA population. Unexpectedly, a G-rich motif was enriched in sequences cross-linked to Ago2 in both the presence and absence of miRNAs. Expression analysis and reporter assays confirmed that the seed-related motif confers miRNA-directed regulation on host mRNAs and that the G-rich motif can modulate this regulation.Leukemia & Lymphoma Society of AmericaUnited States. Public Health Service (Grant R01-GM34277)United States. Public Health Service (Grant R01-CA133404)National Cancer Institute (U.S.) (Grant P01-CA42063)National Cancer Institute (U.S.) Cancer Center Support (Grant P30-CA14051

A novel protocol to maintain continuous access to thawed plasma at a rural trauma center.

BACKGROUND: Early administration of plasma improves mortality in massively transfused patients, but the thawing process causes delay. Small rural centers have been reluctant to maintain thawed plasma due to waste concerns. Our 254-bed rural Level II trauma center initiated a protocol allowing continuous access to thawed plasma, and we hypothesized its implementation would not increase waste or cost. METHODS: Two units of thawed plasma are continuously maintained in the trauma bay blood refrigerator. After 3 days, these units are replaced with freshly thawed plasma and returned to the blood bank for utilization prior to their 5-day expiration date. The blood bank monitors and rotates the plasma. Only trauma surgeons can use the plasma stored in the trauma bay. Wasted units and cost were measured over a 12-month period and compared with the previous 2 years. RESULTS: The blood bank thawed 1127 units of plasma during the study period assigning 274 to the trauma bay. When compared with previous years, we found a significant increase in waste (p \u3c 0.001) and cost (p = 0.020) after implementing our protocol. It cost approximately US $125/month extra to maintain continuous access to thawed plasma during the study period. DISCUSSION: A protocol to maintain thawed plasma in the trauma bay at a rural Level II trauma center resulted in a miniscule increase in waste and cost when considering the scope of maintaining a trauma center. We think this cost is also minimal when compared with the value of having immediate access to thawed plasma. Constant availability of thawed plasma can be offered at smaller rural centers without a meaningful impact on cost. LEVEL OF EVIDENCE: Economic and Value-based Evaluations, Level III