621 research outputs found
An Independence Result on Cotorsion Theories over Valuation Domains
AbstractIt is shown that, over suitable valuation domains R with field of quotients Q, the cotorsion theory GK generated by K=Q/R coincides with the cotorsion theory C∂ cogenerated by the Fuchs' divisible module ∂, provided that Gödel's Axiom of Constructibility V=L is assumed. On the other hand, assuming Martin's Axiom and the negation of the Continuum Hypothesis, it is proved that the cotorsion theory GK is strictly smaller than C∂ by exhibiting a strongly (ℵ1−K)-free divisible module M of projective dimension 2 such that Ext1R(M,K)=0. Applications to Whitehead modules are derived
Covering classes and 1-tilting cotorsion pairs over commutative rings
We are interested in characterising the commutative rings for which a 1-tilting cotorsion pair provides for covers, that is when the class A is a covering class. We use Hrbekšfs bijective correspondence between the 1-tilting cotorsion pairs over a commutative ring R and the faithful finitely generated Gabriel topologies on R. Moreover, we use results of Bazzoni-Positselski, in particular a generalisation of Matlis equivalence and their characterisation of covering classes for 1-tilting cotorsion pairs arising from flat injective ring epimorphisms. Explicitly, if is the Gabriel topology associated to the 1-tilting cotorsion pair, and R is the ring of quotients with respect to, we show that if A is covering, then G is a perfect localisation (in Stenstromšfs sense [B. Stenstrom, Rings of Quotients, Springer, New York, 1975]) and the localisation R has projective dimension at most one as an R-module. Moreover, we show that is covering if and only if both the localisation RG and the quotient rings R/J are perfect rings for every J ∈. Rings satisfying the latter two conditions are called G-almost perfect
The amalgamated duplication of a ring along a multiplicative-canonical ideal
After recalling briefly the main properties of the amalgamated duplication of
a ring along an ideal , denoted by R\JoinI, we restrict our attention
to the study of the properties of R\JoinI, when is a multiplicative
canonical ideal of \cite{hhp}. In particular, we study when every regular
fractional ideal of is divisorial
Almost clean rings and arithmetical rings
It is shown that a commutative B\'ezout ring with compact minimal prime
spectrum is an elementary divisor ring if and only if so is for each
minimal prime ideal . This result is obtained by using the quotient space
of the prime spectrum of the ring modulo the equivalence
generated by the inclusion. When every prime ideal contains only one minimal
prime, for instance if is arithmetical, is Hausdorff and
there is a bijection between this quotient space and the minimal prime spectrum
, which is a homeomorphism if and only if is
compact. If is a closed point of , there is a pure ideal
such that . If is almost clean, i.e. each element is the
sum of a regular element with an idempotent, it is shown that is totally disconnected and, , is
almost clean; the converse holds if every principal ideal is finitely
presented. Some questions posed by Facchini and Faith at the second
International Fez Conference on Commutative Ring Theory in 1995, are also
investigated. If is a commutative ring for which the ring of
quotients of is an IF-ring for each proper ideal , it is proved that
is a strongly discrete valuation ring for each maximal ideal and
is semicoherent for each proper ideal
Tribocorrosion of Pulsed Plasma-Nitrided CoCrMo Implant Alloy
In the present study, a forged CoCrMo (ISO 5832-12) has been subjected to pulsed plasma treatment in a N-2/H-2 atmosphere at low temperatures (below 500 A degrees C). This treatment resulted in the formation of a layer composed by dispersed chromium nitride particles in a N-enriched metal matrix. The materials were tested for corrosion and tribocorrosion performance in 0.9 wt% NaCl at room temperature under controlled electrochemical conditions. After the treatment, the alloy loses its passive nature. The electrode potential was found to critically affect the corrosion and the tribocorrosion rates. In the nitrided alloy, a significant increase of corrosion rate was found at high potentials, while tribocorrosion was determined mainly by mechanical wear and not affected by potential. On the other hand, the untreated CoCrMo alloy exhibited stable corrosion over a wide range of potentials. Its tribocorrosion rate was similar to the nitrided alloy samples at low potentials, but it increased dramatically at high potentials where passivity triggered severe wear-accelerated corrosion and promoted mechanical wear. The present study shows that the electrochemical conditions determine material deterioration and should therefore be considered when selecting materials for tribocorrosion applications such as biomedical implants
Clinical characteristics, neuroimaging findings, and neuropsychological functioning in attention-deficit hyperactivity disorder: Sex differences
Recent clinical studies, in both children/adolescents and adults, have shown the extreme neuropsychological heterogeneity of attention-deficit hyperactivity disorder (ADHD): specific neuropsychological deficits have been found only in a minority of individuals, with no direct correlation between discrete cognitive performances and the trajectory of clinical symptoms. Deficits in specific neuropsychological functions may be common in ADHD, but nevertheless no cognitive or neuropsychological profile may fully explain the disorder. Sex differences in the ADHD presentation, both at a neuropsychological and clinical level, also contribute to this clinical and neuropsychological heterogeneity. At a neuropsychological level, females with ADHD may show greater working memory problems, poorer vocabulary skills and worse visual spatial reasoning. Structural and functional imaging study also show discrete differences across sex; however, the great majority of clinical studies mainly or exclusively include male participants with insufficient data to draw firm conclusions on sex differences within the disorder. Here, we report the recent literature data, discussing still open research questions about the clinical presentation, neuroimaging findings, and neuropsychological functioning in ADHD with a focus on the impact of sex differences—a deeper insight in these unresolved issues may have relevant clinical and therapeutic implications for tailored, effective, and long-lasting interventions
PROTEZIONE CATODICA DEL FONDO DI SERBATOI CON SISTEMI AD ANODI LINEARI DISTRIBUITI. DISTRIBUZIONE DEL POTENZIALE E DELLA CORRENTE
I serbatoi fuori terra di grandi dimensioni per lo stoccaggio di prodotti petroliferi sono sempre più frequentemente posati in opera con membrana di contenimento secondaria in materiale plastico per prevenire contaminazione del suolo in caso di perdite. Per attuare la protezione catodica in presenza di membrana si ricorre a sistemi ad anodi distribuiti, installati nello spazio tra il fondo e la membrana; tra questi, l’anodo del tipo a grid o a nastro in titanio attivato con ossidi di metalli nobili è uno dei più utilizzati. La particolare configurazione geometrica di questo sistema di protezione catodica pone specifici problemi di distribuzione del potenziale e della corrente di protezione. La memoria si sofferma su una serie di aspetti caratteristici di questa applicazione e riporta i risultati di alcune simulazioni numeriche effettuate per prevedere l’effettiva distribuzione di corrente e potenziale
The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involved in inflammation-mediated angiogenesis which is important for wound healing and repair. We employed an oligonucleotide microarray technique to gain further insight into the molecular mechanisms underlying the proangiogenic potential of human PMN. In addition to 18 known angiogenesis-relevant genes, we detected the expression of 10 novel genes, namely midkine, erb-B2, ets-1, transforming growth factor receptor-beta(2) and -beta(3), thrombospondin, tissue inhibitor of metalloproteinase 2, ephrin A2, ephrin B2 and restin in human PMN freshly isolated from the circulation. Gene expression was confi rmed by the RT-PCR technique. In vivo evidence for the role of PMN in neovascularization was provided by studying neovascularization in a skin model of wound healing using CD18-deficient mice which lack PMN infi ltration to sites of lesion. In CD18-deficient animals, neo- vascularization was found to be signifi cantly compromised when compared with wild- type control animals which showed profound neovascularization within the granulation tissue during the wound healing process. Thus, PMN infiltration seems to facilitate inflammation mediated angiogenesis which may be a consequence of the broad spectrum of proangiogenic factors expressed by these cells. Copyright (c) 2006 S. Karger AG, Basel
miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
Excessive or inappropriate activation of the immune system can be deleterious to the organism, warranting multiple molecular mechanisms to control and properly terminate immune responses. MicroRNAs (miRNAs), ~22-nt-long noncoding RNAs, have recently emerged as key posttranscriptional regulators, controlling diverse biological processes, including responses to non-self. In this study, we examine the biological role of miR-146a using genetically engineered mice and show that targeted deletion of this gene, whose expression is strongly up-regulated after immune cell maturation and/or activation, results in several immune defects. Collectively, our findings suggest that miR-146a plays a key role as a molecular brake on inflammation, myeloid cell proliferation, and oncogenic transformation
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