Influence of oxygen supply on the susceptibility of cv. Palomino fino must to browning

Experiments have been conducted on the oxidation of must (cv. Palomino fine). At the initial decanting process prior to fermentation, wines produced from hyperoxidized must had a reduced content of oxidable polyphenolic compounds and a reduced tendency to browning; they maintained these characteristics after bottling. Intermediate doses and the combined use of oxygen and sulphur dioxide were not fully effective in resolving the problem of browning for must of this grape variety, The larger the dose of oxygen (30 mg.l-1), the less the content of hydroxycinnamic esters and the lower the oxidizability, This dose was appropriate for producing a "fino" sherry wine with a low tendency to browning, retaining the sensory characteristics of this particular type of wine

¿SON EFECTIVOS LOS CONSEJOS DE ADMINISTRACIÓN? LA EFICACIA DEL CONSEJO Y LOS RESULTADOS DE LA EMPRESA

Numerosos trabajos han estudiado la influencia del consejo de administración en las decisiones y resultados de sus empresas. No obstante, la enorme popularidad alcanzada en el campo del gobierno corporativo por estos estudios, no viene acompañada por sus resultados, que han sido ambiguos y, a veces, conflictivos En esta investigación proponemos que la efectividad de los consejos depende de las experiencias y conocimientos de los consejeros que lo conforman, así como de la estructura de estos consejos. Entendemos que ambas dimensiones (composición y estructura) no son “por si” suficientes para el logro de consejos plenamente efectivos, pero si se definen como elementos necesarios para ello. Desde nuestra perspectiva, constituyen el potencial que permitirá lograr una adecuada capacidad estratégica por parte del consejo. Nuestros resultados muestran la importancia de las variables que conforman la estructura y composición del consejo (tamaño del consejo, permanencia, experiencia de los consejeros) a la hora de explicar los resultados empresariales

Monitoring, Corporate Performance and Institutional Directors

This is the pre-peer reviewed version of the following article: Monitoring, Corporate Performance and Institutional Directors, which has been published in final form at https://doi.org/10.1111/auar.12262. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.Our main objective is to study the effect of institutional directors on firm performance, distinguishing directors according to whether they maintain business relationships (pressure‐sensitive) or not (pressure‐resistant). Our results show that in weak regulatory and low investor protection environments, institutional directors have a negative impact on corporate performance. Our evidence shows that this negative effect is mainly driven by the role of pressure‐resistant directors and not for those directors representing mainly banks and other financial institutions with a long‐term investment horizon. These findings have implications for numerous parties, such as institutional investors, regulators, potential new board members and other corporate governance reform proponents, who frequently examine board characteristics to assess the effectiveness of boards in value‐creation policies

Liver transplantation for colorectal liver metastasis: Survival without recurrence can be achieved

info:eu-repo/semantics/publishedVersio

Co-Infection with Cryptosporidium meleagridis and Enterocytozoon bieneusi in an HIV+ Colombian Patient

A 44-year-old human immunodeficiency virus-infected (HIV+) female with severe immunodeficiency Category 3 (C3) diagnosed in 2010 was admitted to hospital with acute diarrhoea. She was non-adherent to antiretroviral therapy (ART) and had a previous suspicion of respiratory symptoms with a cough that had been persisting for 15 days. Clinical examination revealed severe immune deterioration (viral load: 109,655 copies/mL; CD4+ count: 14 cells/mm3), respiratory symptoms (negative sputum Gram stain and tuberculosis culture), and neurological deterioration (serological assays negative for Cryptococcus spp. and Toxoplasma gondii). A coproculture was negative for Campylobacter spp., Salmonella spp., and Shigella spp. Ziehl–Neelsen staining of faecal smears revealed the presence of Cryptosporidium spp. oocysts. PCR testing and sequencing confirmed a concomitant infection with C. meleagridis and Enterocytozoon bieneusi. The patient was treated with metronidazole (500 mg every 8 h for 5 days) and nitazoxanide (500 mg every 12 h for 14 days). After requesting voluntary discharge and abandoning ART and parasiticidal treatments, she experienced a dramatic deterioration of her state of health and contact with her was lost. Our results have demonstrated that molecular-based testing improves the detection of opportunistic pathogens that are difficult to detect by routine microscopy, allows for transmission dynamics investigations, and assists in choosing the best chemotherapeutical option.This research was funded by the Health Institute Carlos III (ISCIII) and the Ministry of Economy and Competitiveness (Spain) under project PI16CIII/00024.S

Larger λR\lambda_R in the disc of isolated active spiral galaxies than in their non-active twins

We present a comparison of the spin parameter $\lambda_R$, measured in a region dominated by the galaxy disc, between 20 pairs of nearby (0.005$<$z$<$0.03) seemingly isolated twin galaxies differing in nuclear activity. We find that 80--82% of the active galaxies show higher values of $\lambda_R$ than their corresponding non-active twin(s), indicating larger rotational support in the AGN discs. This result is driven by the 11 pairs of unbarred galaxies, for which 100% of the AGN show larger $\lambda_R$ than their twins. These results can be explained by a more efficient angular momentum transfer from the inflowing gas to the disc baryonic matter in the case of the active galaxies. This gas inflow could have been induced by disc or bar instabilities, although we cannot rule out minor mergers if these are prevalent in our active galaxies. This result represents the first evidence of galaxy-scale differences between the dynamics of active and non-active isolated spiral galaxies of intermediate stellar masses (10$^{10}<M_*<10^{11}$ M$_{\odot}$) in the Local Universe.Comment: 11 pages, 7 figures. Accepted for publication in A&A Letter

Spotting the differences between active and non-active twin galaxies on kpc-scales. A pilot study

We present a pilot study aimed to identify large-scale galaxy properties that could play a role in activating a quiescent nucleus. To do so, we compare the properties of two isolated nearby active galaxies and their non-active twins selected from the Calar Alto Legacy Integral Field Area (CALIFA) survey. This pilot sample includes two barred and two unbarred galaxies. We characterise the stellar and ionised gas kinematics and also their stellar content. We obtain simple kinematic models by fitting the full stellar and ionised gas velocity fields and just the approaching/receding sides. We find that the analysed active galaxies present lopsided disks and higher values of the global stellar angular momentum ($\lambda_{R}$) than their non-active twins. This could be indicating that the stellar disks of the AGN gained angular momentum from the inflowing gas that triggered the nuclear activity. The inflow of gas could have been produced by a twisted disk instability in the case of the unbarred AGN, and by the bar in the case of the barred AGN. In addition, we find that the central regions of the studied active galaxies show older stellar populations than their non-active twins. The next step is to statistically explore these galaxy properties in a larger sample of twin galaxies.Comment: 24 pages, 24 figures. Accepted by MNRA

A survey of the eutrophication state of an urbanized tropical estuary, the case of the Great Vitória Estuarine System, Brazil.

Although, estuarine ecosystems have an ecological and economical importance as they have a high  biological productivity and occur within a unique and dynamic environment, they have been subjected to anthropogenic alterations. The Great Vitória Estuarine System (GVES), Espírito Santo State, Brazil, is not an exception, as urbanization is growing around it with a high quantity of sewage been added to the system. In order to evaluate the eutrophication state as well as the meiofauna response to it, several parameters in both sediments and in the water column were assessed. Orthophosphate, nitrite, nitrate, ammonia, chla and Fecal Coliform counts (FC) ranged from 0.2 to 3.2 μM, 0.25 to 1.14 μM, 1.83 to 0.19μM, 4.19 to 49.23 μM, 0.61 to 6.72 μg/L and 14 to 5.0x104 MPN/100 mL of water, respectively. These results showed that the GVES is under an eutrophication process and that the Passagem Channel experienced the largest impacts. Sewage plays an important role in this eutrophication process as indicated by PCA and correlations tests. The density of meiofauna showed similar values to those found in environments with similar levels of anthropogenic stress. This multi-approach evaluation revealed several aspects of the impacted estuary and could be used as an important tool to manage better the estuary.Although, estuarine ecosystems have an ecological and economical importance as they have a high  biological productivity and occur within a unique and dynamic environment, they have been subjected to anthropogenic alterations. The Great Vitória Estuarine System (GVES), Espírito Santo State, Brazil, is not an exception, as urbanization is growing around it with a high quantity of sewage been added to the system. In order to evaluate the eutrophication state as well as the meiofauna response to it, several parameters in both sediments and in the water column were assessed. Orthophosphate, nitrite, nitrate, ammonia, chla and Fecal Coliform counts (FC) ranged from 0.2 to 3.2 μM, 0.25 to 1.14 μM, 1.83 to 0.19μM, 4.19 to 49.23 μM, 0.61 to 6.72 μg/L and 14 to 5.0x104 MPN/100 mL of water, respectively. These results showed that the GVES is under an eutrophication process and that the Passagem Channel experienced the largest impacts. Sewage plays an important role in this eutrophication process as indicated by PCA and correlations tests. The density of meiofauna showed similar values to those found in environments with similar levels of anthropogenic stress. This multi-approach evaluation revealed several aspects of the impacted estuary and could be used as an important tool to manage better the estuary

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections

Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking geographic variation in incidence and the fact that virus alone is insufficient to cause disease, suggests other co-factors are involved. Here we present epidemiological analysis and genome-wide association study (GWAS) in 4365 individuals from an African population cohort, to assess the influence of host genetic and non-genetic factors on virus antibody responses. EBV/KSHV co-infection (OR = 5.71(1.58–7.12)), HIV positivity (OR = 2.22(1.32–3.73)) and living in a more rural area (OR = 1.38(1.01–1.89)) are strongly associated with immunogenicity. GWAS reveals associations with KSHV antibody response in the HLA-B/C region (p = 6.64 × 10−09). For EBV, associations are identified for VCA (rs71542439, p = 1.15 × 10−12). Human leucocyte antigen (HLA) and trans-ancestry fine-mapping substantiate that distinct variants in HLA-DQA1 (p = 5.24 × 10−44) are driving associations for EBNA-1 in Africa. This study highlights complex interactions between KSHV and EBV, in addition to distinct genetic architectures resulting in important differences in pathogenesis and transmission

Para o estudo da evolução do ensino e da formação em administração educacional em Portugal

Estudos sobre a evolução do ensino de disciplinas, na formação de professores em Portugal, são recentes. O controle burocrático centralizado reteve as dimensões do controle político-administrativo. De certo modo, protegeu a esfera educativa das influências modernizantes, do capitalismo industrial e das lógicas mercantis e gerencialistas. Defendeu a educação do domínio político, da intervenção de movimentos sociais, das propagandas de ideais democráticos e da cidadania. A utilização da designação "Administração educacional" ilustra as dificuldades sentidas, ao longo dos últimos anos, em termos da construção acadêmica de uma área, seja pela falta de tradição, seja pelos antecedentes históricos.In Portugal, studies about the evolution of disciplines teaching in the teachers formation are recent. The centralized bureaucratic control has held back the dimensions of politic administrative control. In a certain way, it has protected the education against the new-fashioned influences, manufacturing capitalism, and mercantile and managerial logics. This centralized bureaucratic control has also profected the education against the politic dominion, the intervention of social movements, the advertising of democratic ideals, and against the citizenship. The use of the term "Educational administration" shows the difficulties met by the searchers along the latest years, since there is no tradiction nor historic antecedence