Geometry of manifolds with area metric: multi-metric backgrounds

We construct the differential geometry of smooth manifolds equipped with an algebraic curvature map acting as an area measure. Area metric geometry provides a spacetime structure suitable for the discussion of gauge theories and strings, and is considerably more general than Lorentzian geometry. Our construction of geometrically relevant objects, such as an area metric compatible connection and derived tensors, makes essential use of a decomposition theorem due to Gilkey, whereby we generate the area metric from a finite collection of metrics. Employing curvature invariants for multi-metric backgrounds we devise a class of gravity theories with inherently stringy character, and discuss gauge matter actions.Comment: 34 pages, REVTeX4, journal versio

Non-Abelian (p,q) Strings in the Warped Deformed Conifold

We calculate the tension of $(p,q)$-strings in the warped deformed conifold using the non-Abelian DBI action. In the large flux limit, we find exact agreement with the recent expression obtained by Firouzjahi, Leblond and Henry-Tye up to and including order $1/M^2$ terms if $q$ is also taken to be large. Furthermore using the finite $q$ prescription for the symmetrised trace operation we anticipate the most general expression for the tension valid for any $(p,q)$. We find that even in this instance, corrections to the tension scale as $1/M^2$ which is not consistent with simple Casimir scaling.Comment: 18 pages, Latex, 1 figure; Added a discussion of the case when the warp factor parameter $b\neq 1$ and typos correcte

Ankle brachial index (ABI) in a cohort of older women in the Philippines: Prevalence of peripheral artery disease and predictors of ABI

Objective: Cardiovascular disease (CVD) is rising in low and middle-income countries, but studies of CVD epidemiology in such settings often focus on risk factors rather than measures of disease progression. Here we use the ankle brachial index (ABI) to assess the prevalence of peripheral artery disease (PAD) among older women living in Metropolitan Cebu, Philippines, and relationships between ABI and CVD risk factors and body composition. Methods: ABI was measured using the Doppler technique in 538 female participants in the 2015 Cebu Longitudinal Health and Nutrition Survey (mean age 58 years, range 47-78 years). ABI was related to a panel of CVD risk factors measured in 2005 and 2012, and to 2012 body composition measures. Results: The prevalence of PAD (1.8%) was among the lowest reported in any comparably-aged sample, and only 9.9% of participants had an ABI indicating borderline PAD risk. Smoking (P < 0.011) and use of CVD medications (P < 0.0001) predicted lower ABI (indicating higher PAD risk), which was also lower in relation to 2012 systolic blood pressure (P < 0.054). ABI was unrelated to other CVD risk factors. An apparent protective relationship between body mass index (BMI) and ABI, noted in previous studies, was found to be confounded by protective relationships between ABI and fat free mass, height, and grip strength (all P < 0.05). Conclusions: The prevalence of PAD is low in Cebu Longitudinal Health and Nutrition Survey participants, and ABI was related to few CVD risk factors. Past reports of lower PAD risk in relation to BMI may reflect confounding by lean mass, which has protective relationships with ABI

Spinor Bose-Einstein Condensates with Many Vortices

Vortex-lattice structures of antiferromagnetic spinor Bose-Einstein condensates with hyperfine spin F=1 are investigated theoretically based on the Ginzburg-Pitaevskii equations near $T_{c}$. The Abrikosov lattice with clear core regions are found {\em never stable} at any rotation drive $\Omega$. Instead, each component $\Psi_{i}$ $(i=0,\pm 1)$ prefers to shift the core locations from the others to realize almost uniform order-parameter amplitude with complicated magnetic-moment configurations. This system is characterized by many competing metastable structures so that quite a variety of vortices may be realized with a small change in external parameters.Comment: 4 page

The Effects of Disorder on the ν=1\nu=1 Quantum Hall State

A disorder-averaged Hartree-Fock treatment is used to compute the density of single particle states for quantum Hall systems at filling factor $\nu=1$. It is found that transport and spin polarization experiments can be simultaneously explained by a model of mostly short-range effective disorder. The slope of the transport gap (due to quasiparticles) in parallel field emerges as a result of the interplay between disorder-induced broadening and exchange, and has implications for skyrmion localization.Comment: 4 pages, 3 eps figure

Rotating spin-1 bosons in the lowest Landau level

We present results for the ground states of a system of spin-1 bosons in a rotating trap. We focus on the dilute, weakly interacting regime, and restrict the bosons to the quantum states in the lowest Landau level (LLL) in the plane (disc), sphere or torus geometries. We map out parts of the zero temperature phase diagram, using both exact quantum ground states and LLL mean field configurations. For the case of a spin-independent interaction we present exact quantum ground states at angular momentum $L\leq N$. For general values of the interaction parameters, we present mean field studies of general ground states at slow rotation and of lattices of vortices and skyrmions at higher rotation rates. Finally, we discuss quantum Hall liquid states at ultra-high rotation.Comment: 24 pages, 14 figures, RevTe

Muscle architecture and passive lengthening properties of the gastrocnemius medialis and Achilles tendon in children who idiopathically toe-walk

Children who idiopathically toe-walk (ITW) habitually operate at greater plantarflexion angles and thus, at shorter muscle-tendon unit (MTU) lengths than typically developing (TD) children. Therefore, it is often assumed that habitual use of the gastrocnemius muscle in this way will cause remodelling of the muscle-tendon architecture compared to TD children. However, the gastrocnemius muscle architecture of children who ITW has never been measured. It is essential that we gain a better understanding of these muscle-tendon properties, to ensure that appropriate clinical interventions can be provided for these children. Five children who ITW (age 8 ± 2 years) and 14 TD children (age 10 ± 2 years) participated in this study. Ultrasound was combined with isokinetic dynamometry and surface electromyography, to measure muscle architecture at common positions and passive lengthening properties of the gastrocnemius muscle and tendon across full range of motion. Regardless of which common condition groups were compared under, both the absolute and normalised to MTU muscle belly and fascicle lengths were always longer, and the Achilles tendon length was always shorter in children who ITW than TD children (p 0.05); however, passive joint stiffness was greater in children who ITW at maximum dorsiflexion (p = 0.001) and at a joint moment common to all participants (p = 0.029). Consequently, the findings of this pilot study indicate a remodelling of the relative MTU that does not support the concept that children who ITW commonly experience muscle shortening. Therefore, greater consideration of the muscle and tendon properties are required when prescribing clinical interventions that aim to lengthen the MTU, and treatments may be better targeted at the Achilles tendon in children who ITW

Dissipative transport in quantum Hall ferromagnets by spin-wave scattering

We report on a study of the effect upon electrical transport of spin-wave scattering from charged quasiparticles in nu = 1 quantum Hall ferromagnets, including both Heisenberg (single layer) and easy-plane (bilayer) cases. We derive a quantum Langevin equation to describe the resulting diffusive motion of the charged particle and use this to calculate the contribution to low-temperature conductivity from a density of charged particles. This conductivity has a power-law dependence upon temperature. The contribution is small at low temperatures increasing to a large value at relatively modest temperatures. We comment upon high-temperature transport and upon the contribution of scattering to the width of the zero bias peak in tunneling conductivity

Strategies for Controlled Placement of Nanoscale Building Blocks

The capability of placing individual nanoscale building blocks on exact substrate locations in a controlled manner is one of the key requirements to realize future electronic, optical, and magnetic devices and sensors that are composed of such blocks. This article reviews some important advances in the strategies for controlled placement of nanoscale building blocks. In particular, we will overview template assisted placement that utilizes physical, molecular, or electrostatic templates, DNA-programmed assembly, placement using dielectrophoresis, approaches for non-close-packed assembly of spherical particles, and recent development of focused placement schemes including electrostatic funneling, focused placement via molecular gradient patterns, electrodynamic focusing of charged aerosols, and others

Meta-analysis of type 2 Diabetes in African Americans Consortium

Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 × 10(-94)<P<5 × 10(-8), odds ratio (OR)  = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 × 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe