79 research outputs found
Variation in the use of definitive treatment options in the management of Graves' disease: a UK clinician survey
Background:
Gravesâ disease can be treated with antithyroid drugs (ATDs), radioiodine or surgery. Use of definitive treatments (radioiodine or surgery) varies widely across centres. Specific clinical circumstances, local facilities, patient and clinician preferences and perceptions will affect choice of treatment. Detailed understanding of UK cliniciansâ views and their rationale for different treatments is lacking.
Aims: To study the preferences and perceptions of UK clinicians on the role of surgery and radioiodine in the management of Gravesâ disease.
Methods: British Thyroid Associationâ (BTA), âSociety for Endocrinologyâ (SFE) and âBritish Association of Endocrine and Thyroid Surgeonsâ (BAETS) members were invited to complete an online survey examining their management decisions in Gravesâ disease and factors that influenced their decisions.
Results: 158 responses from UK consultants were included. The ratio of physicians to surgeons was 11:5 and males to females was 12:4. Most clinicians would commence ATDs in uncomplicated first presentation of Gravesâ disease. A wide range of risk estimates on the effectiveness and risks of treatment was given by clinicians. Radioiodine was used most frequently in relapsed Gravesâ disease. However severe eye disease and pregnancy strongly influenced choice in favour of surgery. Surgeons underestimated the success of radioiodine (P<0.01) and were more likely to recommend thyroidectomy than physicians.
Conclusions: This survey demonstrates significant variation in cliniciansâ perceptions of risks of treatment and their choice of management options for relapsed Gravesâ disease. The variation appeared to be dependent on patient and disease specific factors as well as physician experience, gender and speciality
Trimester-Specific Reference Intervals of Thyroid Function Testing in Pregnant Women from Basrah, Iraq Using Electrochemiluminescent Immunoassay
Neonatal hyperthyroidism in the offspring of mothers with Gravesâ disease treated with radioiodine
A Case Report of Methimazole-Induced Acute Liver Failure Successfully Treated with Liver Transplantation
Sonographic Decreased Echogenicity of Thyroid Parenchyma in Asymptomatic Population: Correlation with Thyroid Function and Thyroid Autoimmune Activity
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