5 research outputs found
Innovative Preparation of Cellulose-Mediated Silver Nanoparticles for Multipurpose Applications: Experiment and Molecular Docking Studies
In recent years, inorganic metal nanoparticle fabrication
by extraction
of a different part of the plant has been gaining more importance.
In this research, cellulose-mediated Ag nanoparticles (cellulose/Ag
NPs) with excellent antibacterial and antioxidant properties and photocatalytic
activity have been synthesized by the microwave-assisted hydrothermal
method. This method is a green, simple, and low-cost method that does
not use any other capping or reducing agents. X-ray diffraction (XRD),
Fourier transform infrared (FTIR), field emission scanning microscopy
(FESEM), transmission electron microscopy (TEM), energy-dispersive
X-ray (EDX), and UV–visible spectroscopic techniques were used
to investigate the structure, morphology, as well as components of
the generated cellulose/Ag NPs. In fact, XRD results confirm the formation
of the face-centered cubic phase of Ag nanoparticles, while the FTIR
spectra showed that the synergy of carbohydrates and proteins is responsible
for the formation of cellulose/Ag NPs by the green method. It was
found that the green-synthesized silver nanoparticles showed good
crystallinity and a size range of about 20–30 nm. The morphology
results showed that cellulose has a cavity-like structure and the
green-synthesized Ag NPs were dispersed throughout the cellulose polymer
matrix. In comparison to cellulose/Ag NPs and Ag nanoparticles, cellulose/Ag
NPs demonstrated excellent antibacterial activity, Proteus mirabilis (MTCC 1771) possessed a maximum
inhibition zone of 18.81.5 mm at 2.5 g/mL, and Staphylococcus
aureus (MTTC 3615) had a minimum inhibition zone of
11.30.5 mm at 0.5 g/mL. Furthermore, cellulose/Ag NPs also exhibited
a significant radical scavenging property against the DDPH free radical,
and there was a higher degradation efficiency compared to pure Ag
NPs against Rhodamine B as 97.38% removal was achieved. Notably, cellulose/Ag
NPs remarkably promoted the transfer and separation of photogenerated
electron–hole (e–/h+) pairs, thereby
offering prospective application of the photodegradation efficiency
for Rhodamine B (RhB) as well as antibacterial applications. With
the findings from this study, we could develop efficient and environmentally
friendly cellulose/Ag nanoparticles using low-cost, environmentally
friendly materials, making them suitable for industrial and technological
applications
Antibacterial, Antioxidant, Larvicidal and Anticancer Activities of Silver Nanoparticles Synthesized Using Extracts from Fruits of Lagerstroemia speciose and Flowers of Couroupita guianensis
The present study aimed to analyze the in vitro antibacterial, antioxidant, larvicidal and cytotoxicity properties of green synthesized silver nanoparticles (Ag NPs) using aqueous extracts from fruits of Lagerstroemia speciosa and flowers of Couropita guinensis. Synthesized Ag NPs were characterized using UV-DRS, FTIR, XRD, DLS, and High-Resolution SEM and TEM analyses. Absorption wavelength was observed at 386 nm by UV-DRS analysis and energy band gap was calculated as 3.24 eV. FTIR analysis showed the existence of various functional groups in the aqueous extract and in the NPs. DLS analysis showed the stability and particle size of the synthesized Ag NPs. SEM analysis revealed that Ag NPs are in a face centered cubic symmetry and spherical shape with a size of 23.9 nm. TEM analysis showed particle size as 29.90 nm. Ag NPs showed antibacterial activity against both Gram-positive and Gram-negative bacteria. DPPH scavenging trait of Ag NPs was ranging from 20.0 ± 0.2% to 62.4 ± 0.3% and observed significant larvicidal activity (LC50 at 0.742 ppm and LC90 at 6.061 ppm) against Culex quinquefasciatus. In vitro cytotoxicity activity of Ag NPs was also tested against human breast cancer (MCF-7) and fibroblast cells (L-929) and found that cells viabilities are ranging (500 to 25 µg/mL) from 52.5 ± 0.4 to 94.0 ± 0.7% and 53.6 ± 0.5 to 90.1 ± 0.8%, respectively. The synthesized Ag NPs have the potential to be used in the various biomedical applications