297 research outputs found
Observation and study of baryonic B decays: B -> D(*) p pbar, D(*) p pbar pi, and D(*) p pbar pi pi
We present a study of ten B-meson decays to a D(*), a proton-antiproton pair,
and a system of up to two pions using BaBar's data set of 455x10^6 BBbar pairs.
Four of the modes (B0bar -> D0 p anti-p, B0bar -> D*0 p anti-p, B0bar -> D+ p
anti-p pi-, B0bar -> D*+ p anti-p pi-) are studied with improved statistics
compared to previous measurements; six of the modes (B- -> D0 p anti-p pi-, B-
-> D*0 p anti-p pi-, B0bar -> D0 p anti-p pi- pi+, B0bar -> D*0 p anti-p pi-
pi+, B- -> D+ p anti-p pi- pi-, B- -> D*+ p anti-p pi- pi-) are first
observations. The branching fractions for 3- and 5-body decays are suppressed
compared to 4-body decays. Kinematic distributions for 3-body decays show
non-overlapping threshold enhancements in m(p anti-p) and m(D(*)0 p) in the
Dalitz plots. For 4-body decays, m(p pi-) mass projections show a narrow peak
with mass and full width of (1497.4 +- 3.0 +- 0.9) MeV/c2, and (47 +- 12 +- 4)
MeV/c2, respectively, where the first (second) errors are statistical
(systematic). For 5-body decays, mass projections are similar to phase space
expectations. All results are preliminary.Comment: 28 pages, 90 postscript figures, submitted to LP0
Literature Mining for the Discovery of Hidden Connections between Drugs, Genes and Diseases
The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use in knowledge retrieval, the co-occurrence method is also well-suited to discover new, hidden relationships between biomedical concepts following a simple ABC-principle, in which A and C have no direct relationship, but are connected via shared B-intermediates. In this paper we describe CoPub Discovery, a tool that mines the literature for new relationships between biomedical concepts. Statistical analysis using ROC curves showed that CoPub Discovery performed well over a wide range of settings and keyword thesauri. We subsequently used CoPub Discovery to search for new relationships between genes, drugs, pathways and diseases. Several of the newly found relationships were validated using independent literature sources. In addition, new predicted relationships between compounds and cell proliferation were validated and confirmed experimentally in an in vitro cell proliferation assay. The results show that CoPub Discovery is able to identify novel associations between genes, drugs, pathways and diseases that have a high probability of being biologically valid. This makes CoPub Discovery a useful tool to unravel the mechanisms behind disease, to find novel drug targets, or to find novel applications for existing drugs
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Measurement of the branching fraction ratios and CP asymmetries in B-→ D0 CP K-decays
We present a preliminary study of and decays, with the reconstructed in the CP-odd
eigenstates , , in the CP-even eigenstates ,
, and in the (non-CP) flavor eigenstate . Using a
sample of about 382 million Y(4S) decays into BBbar pairs, collected with the
BABAR detector operating at the PEP-II asymmetric-energy B Factory at SLAC, we
measure the ratios of the branching fractions R_CP+- and the direct CP
asymmetries A_CP+-. The results are:
R_CP- = 0.81 \pm 0.10 (stat) \pm 0.05 (syst)
R_CP+ = 1.07 \pm 0.10 (stat) \pm 0.04 (syst)
A_CP- = -0.19 \pm 0.12 (stat) \pm 0.02 (syst)
A_CP+ = 0.35 \pm 0.09 (stat) \pm 0.05 (syst
Observation of CP violation in B ->eta/K-0 decays
We present measurements of the time-dependent CP-violation parameters S and C in B-0 -> eta K-'(0) decays. The data sample corresponds to 384 x 10(6) B (B) over bar pairs produced by e(+)e(-) annihilation at the Upsilon(4S). The results are S = 0.58 +/- 0.10 +/- 0.03 and C = -0.16 +/- 0.07 +/- 0.03. We observe mixing-induced CP violation with a significance of 5.5 standard deviations in this b -> s penguin dominated mode
Measurement of the CP asymmetry and branching fraction of B-0 ->rho K-0(0)
We present a measurement of the branching fraction and time-dependent CP asymmetry of B-0 -> POKO. The results are obtained from a data sample of 227 x 10(6) Y(4S) -> BB decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at Stanford Linear Accelerator Center. From a time-dependent maximum likelihood fit yielding 111 +/- 19 signal events, we find B(B-0 -> rho K-0(0)) = (4.9 +/- 0.8 +/- 0.9) x 10(-6), where the first error is statistical and the second systematic. We report the measurement of the CP parameters S-rho 0KS0 = 0.20 +/- 0.52 +/- 0.24 and C-rho 0KS0 = 0.64 +/- 0.41 +/- 0.20
Branching fraction measurements of B+->rho(+)gamma, B-0 ->rho(0)gamma, and B-0 ->omega gamma
We present a study of the decays B+->rho(+)gamma, B-0 ->rho(0)gamma, and B-0 ->omega gamma. The analysis is based on data containing 347x10(6) B (B) over bar events recorded with the BABAR detector at the PEP-II asymmetric B factory. We measure the branching fractions B(B+->rho(+)gamma)=(1.10(-0.33)(+0.37)+/- 0.09)x10(-6) and B(B-0 ->rho(0)gamma)=(0.79(-0.20)(+0.22)+/- 0.06)x10(-6), and set a 90% C.L. upper limit B(B-0 ->omega gamma)(rho/omega)gamma)=(1.25(-0.24)(+0.25)+/- 0.09)x10(-6), from which we determine vertical bar V-td/V-ts vertical bar=0.200(-0.020)(+0.021)+/- 0.015, where the first uncertainty is experimental and the second is theoretical
Measurements of CP-violating asymmetries in B-0 -> a(1)(+/-)(1260)pi(-/+) decays
We present measurements of CP-violating asymmetries in the decay B-0 -> a(1)(+/-)(1260)pi(-/+) with a(1)(+/-)(1260)->pi(-/+)pi(+/-)pi(+/-). The data sample corresponds to 384x10(6) B(b) over bar pairs collected with the BABAR detector at the PEP-II asymmetric B factory at SLAC. We measure the CP-violating asymmetry A(CP)(a1 pi)=-0.07 +/- 0.07 +/- 0.02, the mixing-induced CP violation parameter S-a1 pi=0.37 +/- 0.21 +/- 0.07, the direct CP violation parameter C-a1 pi=-0.10 +/- 0.15 +/- 0.09, and the parameters Delta C-a1 pi=0.26 +/- 0.15 +/- 0.07 and Delta S-a1 pi=-0.14 +/- 0.21 +/- 0.06. From these measured quantities we determine the angle alpha(eff)=78.6 degrees +/- 7.3 degrees
Measurement of branching fractions and charge asymmetries in B decays to an eta meson and a K-* meson
We present measurements of branching fractions and charge asymmetries for the decays B ->eta K-*, where K-* indicates a spin 0, 1, or 2 K pi system. The data sample corresponds to 344x10(6) B (B) over bar pairs collected with the BABAR detector at the PEP-II asymmetric-energy e(+)e(-) collider at SLAC. We measure the branching fractions (in units of 10(-6)): B(B-0 ->eta K-*0(892))=16.5 +/- 1.1 +/- 0.8, B(B+->eta K*+(892))=18.9 +/- 1.8 +/- 1.3, B(B-0 ->eta(K pi)(0)(*0))=11.0 +/- 1.6 +/- 1.5, B(B+->eta(K pi)(0)(*+))=18.2 +/- 2.6 +/- 2.6, B(B-0 ->eta K-2(*0)(1430))=9.6 +/- 1.8 +/- 1.1, and B(B+->eta K-2(*+)(1430))=9.1 +/- 2.7 +/- 1.4. We also determine the charge asymmetries for all decay modes
Search for the highly suppressed decays B- -> K+π-π- and B- -> K-K-π+
We report a search for the decays B- -> K+pi(-)pi(-) and B- -> K-K-pi(+), which are highly suppressed in the standard model. Using a sample of (467 +/- 5) x 10(6) B (B) over bar pairs collected with the BABAR detector, we do not see any evidence of these decays and determine 90% confidence level upper limits of B(B- -> K+pi(-)pi(-)) and K-K-pi(+)) and < 1.6 x 10(-7) on the corresponding branching fractions, including systematic uncertainties
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