Effects of Methylene Blue and Polyethelene Glycol on Facial Nerve Axotomy Recovery

poster abstractInjury and disease are common factors affecting peripheral nerves and can lead to loss of function. Recovery time after an injury is slow and not very efficient in humans. Treatment methods involving methylene blue (MB) and polyethylene glycol (PEG) have shown combinational effects in sciatic nerve axotomies. We are using behavior analysis of eye blink reflex and vibrissae orientation and movement as a measurement of rate of functional recovery. We will have treatment groups of both cut and crush rats. For each group we will be testing the effect of PEG/MB or no treatment control groups. The results of these treatment groups are significant to finding treatment options for clinical use

Which effective viscosity?

Magmas undergoing shear are prime examples of flows that involve the transport of solids and gases by a separate (silicate melt) carrier phase. Such flows are called multiphase, and have attracted much attention due to their important range of engineering applications. Where the volume fraction of the dispersed phase (crystals) is large, the influence of particles on the fluid motion becomes significant and must be taken into account in any explanation of the bulk behaviour of the mixture. For congested magma deforming well in excess of the dilute limit (particle concentrations >40% by volume), sudden changes in the effective or relative viscosity can be expected. The picture is complicated further by the fact that the melt phase is temperature- and shear-rate-dependent. In the absence of a constitutive law for the flow of congested magma under an applied force, it is far from clear which of the many hundreds of empirical formulae devised to predict the rheology of suspensions as the particle fraction increases with time are best suited. Some of the more commonly used expressions in geology and engineering are reviewed with an aim to home in on those variables key to an improved understanding of magma rheology. These include a temperature, compositional and shear-rate dependency of viscosity of the melt phase with the shear-rate dependency of the crystal (particle) packing arrangement. Building on previous formulations, a new expression for the effective (relative) viscosity of magma is proposed that gives users the option to define a packing fraction range as a function of shear stress. Comparison is drawn between processes (segregation, clustering, jamming), common in industrial slurries, and structures seen preserved in igneous rocks. An equivalence is made such that congested magma, viewed in purely mechanical terms as a high-temperature slurry, is an inherently non-equilibrium material where flow at large Péclet numbers may result in shear thinning and spontaneous development of layering

Influence of Impact Parameter on Thermal Description of Relativistic Heavy Ion Collisions at GSI/SIS

Attention is drawn to the role played by the size of the system in the thermodynamic analysis of particle yields in relativistic heavy ion collisions at SIS energies. This manifests itself in the non-linear dependence of K+ and K- yields in $AA$ collisions at 1 -- 2 A.GeV on the number of participants. It is shown that this dependence can be quantitatively well described in terms of a thermal model with a canonical strangeness conservation. The measured particle multiplicity ratios (pi+/p, pi-/pi+, d/p, K+/pi+ and K+/K- but not eta/pi0) in central Au-Au and Ni-Ni collisions at 0.8 -- 2.0 A.GeV are also explained in the context of a thermal model with a common freeze-out temperature and chemical potential. Including the concept of collective flow a consistent picture of particle energy distributions is derived with the flow velocity being strongly impact-parameter dependent.Comment: revtex, 20 figure

Deep sub-arcsecond wide-field imaging of the Lockman Hole field at 144 MHz

Instrumentatio

Measurement of the B0-anti-B0-Oscillation Frequency with Inclusive Dilepton Events

The $B^0$-$\bar B^0$ oscillation frequency has been measured with a sample of 23 million \B\bar B pairs collected with the BABAR detector at the PEP-II asymmetric B Factory at SLAC. In this sample, we select events in which both B mesons decay semileptonically and use the charge of the leptons to identify the flavor of each B meson. A simultaneous fit to the decay time difference distributions for opposite- and same-sign dilepton events gives $\Delta m_d = 0.493 \pm 0.012{(stat)}\pm 0.009{(syst)}$ ps$^{-1}$.Comment: 7 pages, 1 figure, submitted to Physical Review Letter

MIGHTEE : total intensity radio continuum imaging and the COSMOS/XMM-LSS Early Science fields

Please read abstract in the article.The UK Science and Technology Facilities Council; the South African Radio Astronomy Observatory; the Leverhulme Trust through an Early Career Research Fellowship; the South African Research Chairs Initiative of the Department of Science and Technology; the National Research Foundation; the Science and Technology Foundation (FCT, Portugal); the UK STFC ; the South African Research Chairs Initiative of the Department of Science and Innovation; the Bundesministerium für Bildung und Forschung (BMBF); the Italian Ministry of Foreign Affairs and International Cooperation; the South African Department of Science and Technology’s National Research Foundation (DST-NRF).https://academic.oup.com/mnrashj2022Physic

'Disc-jet' coupling in black hole X-ray binaries and active galactic nuclei

In this chapter I will review the status of our phenomenological understanding of the relation between accretion and outflows in accreting black hole systems. This understanding arises primarily from observing the relation between X-ray and longer wavelength (infrared, radio) emission. The view is necessarily a biased one, beginning with observations of X-ray binary systems, and attempting to see if they match with the general observational properties of active galactic nuclei.Comment: 28 pages, 15 figures, To appear in Belloni, T. (ed.): The Jet Paradigm - From Microquasars to Quasars, Lect. Notes Phys. 794 (2009

Measurement of the CP-Violating Asymmetry Amplitude sin2β\beta

We present results on time-dependent CP-violating asymmetries in neutral B decays to several CP eigenstates. The measurements use a data sample of about 88 million Y(4S) --> B Bbar decays collected between 1999 and 2002 with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We study events in which one neutral B meson is fully reconstructed in a final state containing a charmonium meson and the other B meson is determined to be either a B0 or B0bar from its decay products. The amplitude of the CP-violating asymmetry, which in the Standard Model is proportional to sin2beta, is derived from the decay-time distributions in such events. We measure sin2beta = 0.741 +/- 0.067 (stat) +/- 0.033 (syst) and |lambda| = 0.948 +/- 0.051 (stat) +/- 0.017 (syst). The magnitude of lambda is consistent with unity, in agreement with the Standard Model expectation of no direct CP violation in these modes

Detection and localization of early- and late-stage cancers using platelet RNA

Cancer patients benefit from early tumor detection since treatment outcomes are more favorable for less advanced cancers. Platelets are involved in cancer progression and are considered a promising biosource for cancer detection, as they alter their RNA content upon local and systemic cues. We show that tumor-educated platelet (TEP) RNA-based blood tests enable the detection of 18 cancer types. With 99% specificity in asymptomatic controls, thromboSeq correctly detected the presence of cancer in two-thirds of 1,096 blood samples from stage I–IV cancer patients and in half of 352 stage I–III tumors. Symptomatic controls, including inflammatory and cardiovascular diseases, and benign tumors had increased false-positive test results with an average specificity of 78%. Moreover, thromboSeq determined the tumor site of origin in five different tumor types correctly in over 80% of the cancer patients. These results highlight the potential properties of TEP-derived RNA panels to supplement current approaches for blood-based cancer screening