150 research outputs found

    Building a Socio-technical Perspective of Community Resilience with a Semiotic Approach

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    Situated in the diversity and adversity of real-life contexts facing crisis situations, this research aims at boosting the resilience process within communities supported by digital and social technology. In this paper, eight community leaders in different parts of the world are invited to express their issues and wishes regarding the support of technology to face social challenges. Methods and artefacts based on the Organisational Semiotics (OS) and the Socially-Aware computing have been applied to analyse and consolidate this data. By providing both a systemic view of the problem and also leading to the identification of requirements, the analysis evidences some benefits of the OS-based approach to consolidate perspectives from different real-life scenarios towards building a socio-technical solution

    Thinking about Culture in iDTV Projects

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    Interactive Digital Television (iDTV) is a technology that has potential to mitigate economic and social difficulties related to knowledge access and digital inclusion in Brazil. Nevertheless, iDTV solutions did not yet bring anything new and disappointed most users. Thinking about social and cultural issues in iDTV applications might result in design solutions that make sense to people affected by this new communication medium. In this paper, we propose a set of questions to support designers of iDTV applications to address cultural aspects during requirement analysis in a structured way. As practical use example, we apply these questions to prospect requirements from a cultural perspec-tive for an overlaid iDTV application in the real context of a Brazilian Company’s TV show

    Interface de usuário sob a lente de abordagens semióticas

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    Computational systems can be seen as complex networks of signs that can be treated semiotically in several levels. The user interface of such systems can be understood as a "representamen" for the system. Evaluating interfaces in this perspective requires an analysis of the signs present in the interface, relative to the user's language and his/her processes of signification. In this paper we revisit the main approaches to the concept of interface and human-computer interaction, and explore the potential of the semiotic perspective in the understanding and analysis of user interfaces. We argue that Semiotics provides us with an accurate vocabulary and enables us to analyze interfaces under unique aspects. In this paper we apply a combination of semiotic approaches as a basis for a framework to analyze user interfaces. The proposal is illustrated with the analysis of elements of the interface of commercial e-mail systems

    Classification of time series by shapelet transformation

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    Time-series classification (TSC) problems present a specific challenge for classification algorithms: how to measure similarity between series. A \emph{shapelet} is a time-series subsequence that allows for TSC based on local, phase-independent similarity in shape. Shapelet-based classification uses the similarity between a shapelet and a series as a discriminatory feature. One benefit of the shapelet approach is that shapelets are comprehensible, and can offer insight into the problem domain. The original shapelet-based classifier embeds the shapelet-discovery algorithm in a decision tree, and uses information gain to assess the quality of candidates, finding a new shapelet at each node of the tree through an enumerative search. Subsequent research has focused mainly on techniques to speed up the search. We examine how best to use the shapelet primitive to construct classifiers. We propose a single-scan shapelet algorithm that finds the best kk shapelets, which are used to produce a transformed dataset, where each of the kk features represent the distance between a time series and a shapelet. The primary advantages over the embedded approach are that the transformed data can be used in conjunction with any classifier, and that there is no recursive search for shapelets. We demonstrate that the transformed data, in conjunction with more complex classifiers, gives greater accuracy than the embedded shapelet tree. We also evaluate three similarity measures that produce equivalent results to information gain in less time. Finally, we show that by conducting post-transform clustering of shapelets, we can enhance the interpretability of the transformed data. We conduct our experiments on 29 datasets: 17 from the UCR repository, and 12 we provide ourselve

    Monitoramento de safras via Web: um caso de sucesso em pesquisa multidisciplinar.

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    Este trabalho descreve o projeto WebMaps em desenvolvimento na UNICAMP, um esforço multidisciplinar envolvendo ciências agrárias e de computação , cujo objetivo é desenvolver uma plataforma baseada em serviços Web para o planejamento agro-ambiental.SBIAgro 2007

    Dynamics of Action Potential Initiation in the GABAergic Thalamic Reticular Nucleus In Vivo

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    Understanding the neural mechanisms of action potential generation is critical to establish the way neural circuits generate and coordinate activity. Accordingly, we investigated the dynamics of action potential initiation in the GABAergic thalamic reticular nucleus (TRN) using in vivo intracellular recordings in cats in order to preserve anatomically-intact axo-dendritic distributions and naturally-occurring spatiotemporal patterns of synaptic activity in this structure that regulates the thalamic relay to neocortex. We found a wide operational range of voltage thresholds for action potentials, mostly due to intrinsic voltage-gated conductances and not synaptic activity driven by network oscillations. Varying levels of synchronous synaptic inputs produced fast rates of membrane potential depolarization preceding the action potential onset that were associated with lower thresholds and increased excitability, consistent with TRN neurons performing as coincidence detectors. On the other hand the presence of action potentials preceding any given spike was associated with more depolarized thresholds. The phase-plane trajectory of the action potential showed somato-dendritic propagation, but no obvious axon initial segment component, prominent in other neuronal classes and allegedly responsible for the high onset speed. Overall, our results suggest that TRN neurons could flexibly integrate synaptic inputs to discharge action potentials over wide voltage ranges, and perform as coincidence detectors and temporal integrators, supported by a dynamic action potential threshold

    Elimination of fibrin Îł-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi

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    The onset of venous thromboembolism, including pulmonary embolism, represents a significant health burden affecting more than 1 million people annually worldwide. Current treatment options are based on anticoagulation, which is suboptimal for preventing further embolic events. In order to develop better treatments for thromboembolism, we sought to understand the structural and mechanical properties of blood clots and how this influences embolism in vivo. We developed a murine model in which fibrin γ-chain cross-linking by activated Factor XIII is eliminated (FGG3X) and applied methods to study thromboembolism at whole-body and organ levels. We show that FGG3X mice have a normal phenotype, with overall coagulation parameters and platelet aggregation and function largely unaffected, except for total inhibition of fibrin γ-chain cross-linking. Elimination of fibrin γ-chain cross-linking resulted in thrombi with reduced strength that were prone to fragmentation. Analysis of embolism in vivo using Xtreme optical imaging and light sheet microscopy demonstrated that the elimination of fibrin γ-chain cross-linking resulted in increased embolization without affecting clot size or lysis. Our findings point to a central previously unrecognized role for fibrin γ-chain cross-linking in clot stability. They also indirectly indicate mechanistic targets for the prevention of thrombosis through selective modulation of fibrin α-chain but not γ-chain cross-linking by activated Factor XIII to reduce thrombus size and burden, while maintaining clot stability and preventing embolism
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