1,489 research outputs found
A Dendrite-Autonomous Mechanism for Direction Selectivity in Retinal Starburst Amacrine Cells
Detection of image motion direction begins in the retina, with starburst amacrine cells (SACs) playing a major role. SACs generate larger dendritic Ca2+ signals when motion is from their somata towards their dendritic tips than for motion in the opposite direction. To study the mechanisms underlying the computation of direction selectivity (DS) in SAC dendrites, electrical responses to expanding and contracting circular wave visual stimuli were measured via somatic whole-cell recordings and quantified using Fourier analysis. Fundamental and, especially, harmonic frequency components were larger for expanding stimuli. This DS persists in the presence of GABA and glycine receptor antagonists, suggesting that inhibitory network interactions are not essential. The presence of harmonics indicates nonlinearity, which, as the relationship between harmonic amplitudes and holding potential indicates, is likely due to the activation of voltage-gated channels. [Ca2+] changes in SAC dendrites evoked by voltage steps and monitored by two-photon microscopy suggest that the distal dendrite is tonically depolarized relative to the soma, due in part to resting currents mediated by tonic glutamatergic synaptic input, and that high-voltageâactivated Ca2+ channels are active at rest. Supported by compartmental modeling, we conclude that dendritic DS in SACs can be computed by the dendrites themselves, relying on voltage-gated channels and a dendritic voltage gradient, which provides the spatial asymmetry necessary for direction discrimination
Full oxide heterostructure combining a high-Tc diluted ferromagnet with a high-mobility conductor
We report on the growth of heterostructures composed of layers of the
high-Curie temperature ferromagnet Co-doped (La,Sr)TiO3 (Co-LSTO) with
high-mobility SrTiO3 (STO) substrates processed at low oxygen pressure. While
perpendicular spin-dependent transport measurements in STO//Co-LSTO/LAO/Co
tunnel junctions demonstrate the existence of a large spin polarization in
Co-LSTO, planar magnetotransport experiments on STO//Co-LSTO samples evidence
electronic mobilities as high as 10000 cm2/Vs at T = 10 K. At high enough
applied fields and low enough temperatures (H < 60 kOe, T < 4 K) Shubnikov-de
Haas oscillations are also observed. We present an extensive analysis of these
quantum oscillations and relate them with the electronic properties of STO, for
which we find large scattering rates up to ~ 10 ps. Thus, this work opens up
the possibility to inject a spin-polarized current from a high-Curie
temperature diluted oxide into an isostructural system with high-mobility and a
large spin diffusion length.Comment: to appear in Phys. Rev.
Analysis of Dynamic Brain Imaging Data
Modern imaging techniques for probing brain function, including functional
Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging,
and magnetoencephalography, generate large data sets with complex content. In
this paper we develop appropriate techniques of analysis and visualization of
such imaging data, in order to separate the signal from the noise, as well as
to characterize the signal. The techniques developed fall into the general
category of multivariate time series analysis, and in particular we extensively
use the multitaper framework of spectral analysis. We develop specific
protocols for the analysis of fMRI, optical imaging and MEG data, and
illustrate the techniques by applications to real data sets generated by these
imaging modalities. In general, the analysis protocols involve two distinct
stages: `noise' characterization and suppression, and `signal' characterization
and visualization. An important general conclusion of our study is the utility
of a frequency-based representation, with short, moving analysis windows to
account for non-stationarity in the data. Of particular note are (a) the
development of a decomposition technique (`space-frequency singular value
decomposition') that is shown to be a useful means of characterizing the image
data, and (b) the development of an algorithm, based on multitaper methods, for
the removal of approximately periodic physiological artifacts arising from
cardiac and respiratory sources.Comment: 40 pages; 26 figures with subparts including 3 figures as .gif files.
Originally submitted to the neuro-sys archive which was never publicly
announced (was 9804003
Effects of strong density fluctuations at the plasma edge on ECEI measurements at ASDEX Upgrade
EUROfusion Consortium 63305
Effects of density gradients and fluctuations at the plasma edge on ECEI measurements at ASDEX Upgrade
Electron cyclotron emission imaging (ECEI) provides measurements of electron temperature (Te) and its fluctuations (ÎŽTe). However, when measuring at the plasma edge, in the steep gradient region, radiation transport effects must be taken into account. It is shown that due to these effects, the scrape-off layer region is not accessible to the ECEI measurements in steady state conditions and that the signal is dominated by the shine-through emission. Transient effects, such as filaments, can change the radiation transport locally, but cannot be distinguished from the shine-through. Local density measurements are essential for the correct interpretation of the electron cyclotron emission, since the density fluctuations influence the temperature measurements at the plasma edge. As an example, a low frequency 8 kHz mode, which causes 10%â15% fluctuations in the signal level of the ECEI, is analysed. The same mode has been measured with the lithium beam emission spectroscopy density diagnostic, and is very well correlated in time with high frequency magnetic fluctuations. With radiation transport modelling of the electron cyclotron radiation in the ECEI geometry, it is shown that the density contributes significantly to the radiation temperature (Trad) and the experimental observations have shown the amplitude modulation in both density and temperature measurements. The poloidal velocity of the low frequency mode measured by the ECEI is 3 km sâ1. The calculated velocity of the high frequency mode measured with the magnetic pick-up coils is about 25 km sâ1. Velocities are compared with the E Ă B background flow velocity and possible explanations for the origin of the low frequency mode are discussed.EUROfusion Consortium 63305
DFR Perturbative Quantum Field theory on Quantum Space Time, and Wick Reduction
We discuss the perturbative approach a` la Dyson to a quantum field theory
with nonlocal self-interaction :phi*...*phi:, according to Doplicher,
Fredenhagen and Roberts (DFR). In particular, we show that the Wick reduction
of non locally time--ordered products of Wick monomials can be performed as
usual, and we discuss a very simple Dyson diagram.Comment: 15 pages, pdf has active hyperlinks. To appear in the proceedings of
the conference on "Rigorous quantum Field Theory", held at Saclay on July
19-21, 2004, on the occasion of Jacques Bros' 70th birthda
Synthesis and reactivities of conducting hexathienylbenzene-co-poly(3-hexylthiophene) star-branched copolymer as donor material for organic photovoltaic cell
The hexathienylbenzene-co-poly(3-hexylthiophene-2,5diyl) (HTB-co-P3HT) conducting
polymer was synthesized by oxidative co-polymerization of hexathienylbenzene (HTB)
and 3-hexylthiophene using iron chloride (FeCl3) as an oxidant. The effect of
chlorobenzene, toluene and chloroform on the optoelectronic characteristics of the
polymer was investigated. The study revealed that spectroscopic and electrochemical
responses of HTB-co-P3HT are affected by the nature of the solvent. The lowest
unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO)
energy levels of HTB-co-P3HT were determined from cyclic voltammetry (CV) and were
compared to those of (6,6)-Phenyl C71 butyric acid methyl ester (PC71BM) and it was
found that the LUMO energy levels of HTB-co-P3HT in toluene were lower than those for
chlorobenzene and chloroform
The quest for companions to post-common envelope binaries. II. NSVS14256825 and HS0705+6700
We report new mid-eclipse times of the two close binaries NSVS14256825 and
HS0705+6700, harboring an sdB primary and a low-mass main-sequence secondary.
Both objects display clear variations in the measured orbital period, which can
be explained by the action of a third object orbiting the binary. If this
interpretation is correct, the third object in NSVS14256825 is a giant planet
with a mass of roughly 12 M_Jup. For HS0705+6700, we provide evidence that
strengthens the case for the suggested periodic nature of the eclipse time
variation and reduces the uncertainties in the parameters of the brown dwarf
implied by that model. The derived period is 8.4 yr and the mass is 31 M_Jup,
if the orbit is coplanar with the binary. This research is part of the
PlanetFinders project, an ongoing collaboration between professional
astronomers and student groups at high schools.Comment: Accepted by Astron. and Astrophy
First imaging results from the Iapetus B/C flyby of the Cassini spacecraft
Cassini had a relatively close flyby at Iapetus on New Year's Eve 2005. The 288 ISS images set various constraints on the origin theories of the dark/bright dichotomy, as revealed multiple surface structures at up to 740 m/pxl size
Gain in Stochastic Resonance: Precise Numerics versus Linear Response Theory beyond the Two-Mode Approximation
In the context of the phenomenon of Stochastic Resonance (SR) we study the
correlation function, the signal-to-noise ratio (SNR) and the ratio of output
over input SNR, i.e. the gain, which is associated to the nonlinear response of
a bistable system driven by time-periodic forces and white Gaussian noise.
These quantifiers for SR are evaluated using the techniques of Linear Response
Theory (LRT) beyond the usually employed two-mode approximation scheme. We
analytically demonstrate within such an extended LRT description that the gain
can indeed not exceed unity. We implement an efficient algorithm, based on work
by Greenside and Helfand (detailed in the Appendix), to integrate the driven
Langevin equation over a wide range of parameter values. The predictions of LRT
are carefully tested against the results obtained from numerical solutions of
the corresponding Langevin equation over a wide range of parameter values. We
further present an accurate procedure to evaluate the distinct contributions of
the coherent and incoherent parts of the correlation function to the SNR and
the gain. As a main result we show for subthreshold driving that both, the
correlation function and the SNR can deviate substantially from the predictions
of LRT and yet, the gain can be either larger or smaller than unity. In
particular, we find that the gain can exceed unity in the strongly nonlinear
regime which is characterized by weak noise and very slow multifrequency
subthreshold input signals with a small duty cycle. This latter result is in
agreement with recent analogue simulation results by Gingl et al. in Refs. [18,
19].Comment: 22 pages, 5 eps figures, submitted to PR
- âŠ