The consequences of measurement error when estimating the impact of BMI on labour market outcomes

This paper uses data on both self-reported and true measures of individual Body Mass Index (BMI) to examine the nature of measurement error in self-reported BMI and to look at the consequences of using self-reported measures when estimating the effect of BMI on economic outcomes. In keeping with previous studies we find that self-reported BMI is subject to significant measurement error and this error is negatively correlated with the true measure of BMI. In our analysis this non-classical measurement error causes the traditional approach to overestimate the relationship between BMI and both income and education. Furthermore we show that popular alternatives estimators that have been adopted to address problems of measurement error in BMI, such as the conditional expectation approach and the instrumental variables approach, also exhibit significant biases

Estimating obesity rates in the presence of measurement error

Reliable measures of obesity are essential in order to develop effective policies to tackle the costs of obesity. In this paper we examine what, if anything, we can learn about obesity rates using self-reported BMI once we allow for possible measurement error. We combine self-reported data on BMI with estimated misclassification rates obtained from auxiliary data to derive upper and lower bounds for the population obesity rate for ten European countries. For men it is possible to obtain meaningful comparisons across countries even after accounting for measurement error. In particular the self-reported data identifies a set of low obesity countries consisting of Denmark, Ireland, Italy, Greece and Portugal and a set of high obesity countries consisting of Spain and Finland. However, it is more difficult to rank countries by female obesity rates. Meaningful rankings only emerge when the misclassification rate is bounded at a level that is much lower than that observed in auxiliary data. A similar limit on misclassification rates is also needed before we can begin to observe meaningful gender differences in obesity rates within countries

Gender, single-sex schooling and maths achievement

This paper examines the determinants of mathematical achievement among primary school children. Previous studies have found that boys perform better in maths than girls, particularly at the upper end of the distribution. It has been suggested in the literature that differences in the size of the maths gap across countries may be explained by differences in the prevalence of single-sex schooling. The Irish education system is interesting both for the fact that a sizeable proportion of children attend single-sex schools, and because these single-sex schools are part of the general educational system, rather than serving a particular socio-economic group. We exploit this fact to test whether the gender composition of schools affects the maths differential at the top of the distribution. In keeping with research on other countries, we find a significant maths gap in favour of boys, but contrary to suggestions in the literature, our results provide no evidence that single-sex schooling reduces the gap. If anything, the gender differential is larger for children educated in single-sex schools than in co-educational schools. These findings are not affected by the inclusion of a proxy for early childhood ability or by the use of instrumental variables to control for potentially endogenous school choice

Impact of employees' character strengths of wisdom on stress and creative performance

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90584/1/j.1748-8583.2010.00157.x.pd

Metabolic rates are significantly lower in abyssal Holothuroidea than in shallow-water Holothuroidea

Recent analyses of metabolic rates in fishes, echinoderms, crustaceans and cephalopods have concluded that bathymetric declines in temperature- and mass-normalized metabolic rate do not result from resource-limitation (e.g. oxygen or food/chemical energy), decreasing temperature or increasing hydrostatic pressure. Instead, based on contrasting bathymetric patterns reported in the metabolic rates of visual and non-visual taxa, declining metabolic rate with depth is proposed to result from relaxation of selection for high locomotory capacity in visual predators as light diminishes. Here, we present metabolic rates of Holothuroidea, a non-visual benthic and benthopelagic echinoderm class, determined in situ at abyssal depths (greater than 4000 m depth). Mean temperature- and mass-normalized metabolic rate did not differ significantly between shallow-water (less than 200 m depth) and bathyal (200–4000 m depth) holothurians, but was significantly lower in abyssal (greater than 4000 m depth) holothurians than in shallow-water holothurians. These results support the dominance of the visual interactions hypothesis at bathyal depths, but indicate that ecological or evolutionary pressures other than biotic visual interactions contribute to bathymetric variation in holothurian metabolic rates. Multiple nonlinear regression assuming power or exponential models indicates that in situ hydrostatic pressure and/or food/chemical energy availability are responsible for variation in holothurian metabolic rates. Consequently, these results have implications for modelling deep-sea energetics and processes

Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition

Inositol phosphates (InsPs) are signaling molecules with multiple roles in cells. In particular Graphic (InsP6) is involved in mRNA export and editing or chromatin remodeling among other events. InsP6 accumulates as mixed salts (phytate) in storage tissues of plants and plays a key role in their physiology. Human diets that are exclusively grain-based provide an excess of InsP6 that, through chelation of metal ions, may have a detrimental effect on human health. Ins(1,3,4,5,6)P5 2-kinase (InsP5 2-kinase or Ipk1) catalyses the synthesis of InsP6 from InsP5 and ATP, and is the only enzyme that transfers a phosphate group to the axial 2-OH of the myo-inositide. We present the first structure for an InsP5 2-kinase in complex with both substrates and products. This enzyme presents a singular structural region for inositide binding that encompasses almost half of the protein. The key residues in substrate binding are identified, with Asp368 being responsible for recognition of the axial 2-OH. This study sheds light on the unique molecular mechanism for the synthesis of the precursor of inositol pyrophosphates

Sprouty2 mediated tuning of signalling is essential for somite myogenesis

Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development. Sprouty2 (Spry2) negatively regulates receptor tyrosine kinases (RTK) and FGF signalling and is important in differentiation, cell migration and proliferation. In vertebrate embryos, Spry2 is expressed in paraxial mesoderm and in forming somites. Expression is maintained in the myotome until late stages of somite differentiation. However, its role and mode of action during somite myogenesis is still unclear. Results: Here, we analysed chick Spry2 expression and showed that it overlaps with that of myogenic regulatory factors MyoD and Mgn. Targeted mis-expression of Spry2 led to inhibition of myogenesis, whilst its C-terminal domain led to an increased number of myogenic cells by stimulating cell proliferation. Conclusions: Spry2 is expressed in somite myotomes and its expression overlaps with myogenic regulatory factors. Overexpression and dominant-negative interference showed that Spry2 plays a crucial role in regulating chick myogenesis by fine tuning of FGF signaling through a negative feedback loop. We also propose that mir-23, mir-27 and mir-128 could be part of the negative feedback loop mechanism. Our analysis is the first to shed some light on in vivo Spry2 function during chick somite myogenesis

Biologie de reproduction chez Thaumatococcus Daniellii (benn.) Benth. et hook. (marantaceae) en Côte D’ivoire

Le processus de reproduction de Thaumatococcus daniellii a été étudié en vue d'une domestication à but économique. Ainsi, l'identification des animaux contribuant à la pollinisation a été réalisée à partir d'observations effectuées dans un dispositif expérimental réglementant l'accès différentiel des animaux aux parcelles. Une pollinisation manuelle suivie de l'analyse des fruits, par rapport à la teneur engraines, ont été effectuées. Les résultats ont révélé l'intervention d'agents extérieurs dans le processus de pollinisation, impliquant un phénomène d'allogamie chez cette plante. Ces agents extérieurs qui agissent en synergie sont Nectarinia olivacea (oiseau) et Aphis sp. (puceron). La prépondérance des fruits contenant une graine,l'échec élevé de l'autopollinisation et la prédominance d'une l'allopollinisation traduisent une incompatibilité génétique dans la régulation de la pollinisation des fleurs chez cette plante

Letter from the Consistory of Rijssen to Rev. A. C. Van Raalte

A letter from the consistory in Rijsen to Rev. Albertus C. Van Raalte releasing Van Raalte from his service to the Rijssen congregation. Apparently V.R. assisted this congregation in becoming established while he was serving the Ommen congregation.https://digitalcommons.hope.edu/vrp_1840s/1001/thumbnail.jp