Book Reviews

Reviews of the following books: Portland: A publication of Greater Portland Landmarks, Inc. Text by Josephine H. Detmer and Patricia M. Pancoast; That Wild Fellow John Neal and the American Literary Revolution by Benjamin Leas

CO Line Emission and Absorption from the HL Tau Disk: Where is all the dust?

We present high-resolution infrared spectra of HL Tau, a heavily embedded young star. The spectra exhibit broad emission lines of hot CO gas as well as narrow absorption lines of cold CO gas. The column density for this cooler material (7.5+/-0.2 x 10^18 cm-2) indicates a large column of absorbing gas along the line of sight. In dense interstellar clouds, this column density of CO gas is associated with Av~52 magnitudes. However, the extinction toward this source (Av~23) suggests that there is less dust along the line of sight than inferred from the CO absorption data. We discuss three possibilities for the apparent paucity of dust along the line of sight through the flared disk: 1) the dust extinction has been underestimated due to differences in circumstellar grain properties, such as grain agglomeration; 2) the effect of scattering has been underestimated and the actual extinction is much higher; or (3) the line of sight through the disk is probing a gas-rich, dust-depleted region, possibly due to the stratification of gas and dust in a pre-planetary disk.Comment: To be published in The Astrophysical Journa

Topiramate in add-on therapy: Results from an open-label, observational study

SummaryAn open-label, observational prospective study assessed the effectiveness of topiramate (TPM) as add-on therapy. A total of 450 patients aged 12 and above with a diagnosis of epilepsy and at least one epileptic seizure during the 12-week retrospective baseline were to be documented. After baseline evaluation, topiramate was added. Ninety-five percent of patients had at least one baseline AED, most commonly Carbamazepine (53%) or Valproate (34%). In 5% TPM was started in monotherapy. Topiramate dose titration and target dose was determined by clinical response and side effect profile. Patients were intended to be followed for a total of 1 year which included 6 visits during which seizure frequency, adverse events, weight as well as clinical global impression were recorded. During the 12 weeks retrospective baseline, a median of 2.8 seizures per month were recorded which reduced significantly to 0.7 per month during the complete treatment phase (p<0.0001). Seventy-two percent of patients had a ≥50% seizure reduction. Ten percent of patients were seizure free during the study. The most commonly reported adverse events were difficulties with memory (4.2%), somnolence (3.6%), and dizziness (2.7%). Overall, topiramate was well tolerated, and only 5% of patients discontinued treatment due to an adverse event. Retention in the study was higher than previously reported during randomized, dose controlled studies and is likely due to individualized doses as well as slower titration used

Ultrafast modulation of the chemical potential in BaFe2As2 by coherent phonons

Time- and angle-resolved extreme ultraviolet photoemission spectroscopy is used to study the electronic structure dynamics in BaFe2As2 around the high-symmetry points Γ and M. A global oscillation of the Fermi level at the frequency of the A1g(As) phonon mode is observed. It is argued that this behavior reflects a modulation of the effective chemical potential in the photoexcited surface region that arises from the high sensitivity of the band structure near the Fermi level to the A1g(As) phonon mode combined with a low electron diffusivity perpendicular to the layers. The results establish a novel way to tune the electronic properties of iron pnictides: coherent control of the effective chemical potential. The results further suggest that the equilibration time for the effective chemical potential needs to be considered in the ultrafast electronic structure dynamics of materials with weak interlayer coupling. © 2014 American Physical Society