514 research outputs found
Vinculando la danza y la educación: el caso del internado Beatriz Hernández
Informe que muestra el proceso de sistematización y teorización de gestión del conocimiento realizado para instalar el proyecto “La danza clásica desde la mirada educativa: una propuesta para la educación del cuerpo” en el internado para niñas de bajos recursos Beatriz Hernández, el cual depende de la Secretaría de Educación Jalisco (SEJ). Este proyecto tuvo el objetivo de diseñar un método educativo basado en la danza y en la conversación para incidir en el conocimiento del cuerpo, el desarrollo cognitivo y el socioafectivo de las alumnas del internado y lograr instalar este método como parte del currículo de la institución. Los resultados de este proyecto permiten tener un nuevo acercamiento al conocimiento de la práctica de la danza como herramienta metodológica para favorecer, por su naturaleza física, expresiva y cognitiva, la integración de mente, cuerpo y emociones. Además, posibilita abrir espacios para ampliar la visión tradicional de los procesos de cognición, aporta nuevos recursos a los normalmente utilizados en el currículo escolar, abre la reflexión sobre el cuerpo como medio de exploración y apropiación de los conocimientos y contribuye a la vinculación de la educación y el arte al proponer la danza como estrategia de formación en el currículo escolar. *A lo largo de este trabajo, la autora hace referencia a entrevistas y registros de clases en audio y video, los cuales no están agregados en este registro
3′UTR Deletion of NONO Leads to Corpus Callosum Anomaly, Left Ventricular Non-Compaction and Ebstein’s Anomaly in a Male Fetus
NONO (Non-Pou Domain-Containing Octamer-Binding Protein) gene maps on chromosome Xq13.1 and hemizygous loss-of-function nucleotide variants are associated with an emerging syndromic form of intellectual developmental disorder (MRXS34; MIM #300967), characterized by developmental delay, intellectual disability, poor language, dysmorphic facial features, and microcephaly. Structural brain malformation, such as corpus callosum and cerebellar abnormalities, and heart defects, in particular left ventricular non-compaction (LVNC), represent the most recurrent congenital malformations, recorded both in about 80% of patients, and can be considered the distinctive imaging findings of this disorder. We present on a further case of NONO-related disease; prenatally diagnosed in a fetus with complete corpus callosum agenesis; absence of septum pellucidum; pericallosal artery; LVNC and Ebstein’s anomaly. A high-resolution microarray analysis demonstrated the presence of a deletion affecting the NONO 3′UTR; leading to a marked hypoexpression of the gene and the complete absence of the protein in cultured amniocytes. This case expands the mutational spectrum of MRXS34, advises to evaluate NONO variants in pre- and postnatal diagnosis of subjects affected by LVNC and other heart defects, especially if associated with corpus callosum anomalies and confirm that CNVs (Copy Number Variants) represent a non-negligible cause of Mendelian disorders
The burden of hypertension and kidney disease in northeast India : the institute for Indian mother and child noncommunicable diseases project
Chronic noncommunicable diseases (NCDs) such as hypertension, atherosclerosis, acute myocardial infarction, stroke, diabetes, obesity, and chronic kidney disease are the major cause of death not only in high income, but also in medium and low income countries. Hypertension and diabetes, the most common causes of chronic kidney disease, are particularly common in southeast Asian Countries. Because early intervention can markedly slow the progression of these two killer diseases, assessment of their presence through screening and intervention program is a priority. We summarize here results of the screening activities and the perspectives of a noncommunicable diseases project started in West Bengal, India, in collaboration with the Institute for Indian Mother and Child (IIMC), a nongovernmental voluntary organization committed to promoting child and maternal health. We started investigating hypertension and chronic kidney disease with screen in school-age children and in adults >30 years old. We found a remarkable prevalence of hypertension, even in underweight subjects, in both children and adult populations. A glomerular filtration rate <60 mL/min was found in 4.1% of adult subjects significantly higher than that of 0.8% to 1.4% reported 10 years ago. Increased awareness and intervention projects to identify NCDs and block their progression are necessary in all countries
Troubling travellers: are ecologically harmful alien species associated with particular introduction pathways?
Prioritization of introduction pathways is seen as an important component of the management of biological
invasions. We address whether established alien plants, mammals, freshwater fish and terrestrial
invertebrates with known ecological impacts are associated with particular introduction pathways (release,
escape, contaminant, stowaway, corridor and unaided). We used the information from the European alien
species database DAISIE (www.europe-aliens.org) supplemented by the EASIN catalogue (European Alien
Species Information Network), and expert knowledge.
Plants introduced by the pathways release, corridor and unaided were disproportionately more likely
to have ecological impacts than those introduced as contaminants. In contrast, impacts were not associated
with particular introduction pathways for invertebrates, mammals or fish. Thus, while for plants
management strategies should be targeted towards the appropriate pathways, for animals, management
should focus on reducing the total number of taxa introduced, targeting those pathways responsible for
high numbers of introductions. However, regardless of taxonomic group, having multiple introduction
pathways increases the likelihood of the species having an ecological impact. This may simply reflect that
species introduced by multiple pathways have high propagule pressure and so have a high probability of
establishment. Clearly, patterns of invasion are determined by many interacting factors and management
strategies should reflect this complexity
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Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment
LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7 tonnes, LZ will search primarily for low-energy interactions with weakly interacting massive particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000 live day run using a 5.6-tonne fiducial mass, LZ is projected to exclude at 90% confidence level spin-independent WIMP-nucleon cross sections above 1.4×10-48 cm2 for a 40 GeV/c2 mass WIMP. Additionally, a 5σ discovery potential is projected, reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of 2.3×10-43 cm2 (7.1×10-42 cm2) for a 40 GeV/c2 mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020
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Projected sensitivity of the LUX-ZEPLIN experiment to the 0νββ decay of Xe 136
The LUX-ZEPLIN (LZ) experiment will enable a neutrinoless double β decay search in parallel to the main science goal of discovering dark matter particle interactions. We report the expected LZ sensitivity to Xe136 neutrinoless double β decay, taking advantage of the significant (>600 kg) Xe136 mass contained within the active volume of LZ without isotopic enrichment. After 1000 live-days, the median exclusion sensitivity to the half-life of Xe136 is projected to be 1.06×1026 years (90% confidence level), similar to existing constraints. We also report the expected sensitivity of a possible subsequent dedicated exposure using 90% enrichment with Xe136 at 1.06×1027 years
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