X-ray background and its correlation with the 21 cm signal

We use high resolution hydrodynamical simulations to study the contribution to the X-ray background from high-$z$ energetic sources, such as X-ray binaries, accreting nuclear black holes and shock heated interstellar medium. Adopting the model discussed in Eide et al. (2018), we find that these X-ray sources during the Epoch of Reionization (EoR) contribute less than a few percent of the unresolved X-ray background. The same sources contribute to less than $\sim$2\% of the measured angular power spectrum of the fluctuations of the X-ray background. The outputs of radiative transfer simulations modeling the EoR are used to evaluate the cross-correlations of X-ray background with the 21~cm signal from neutral hydrogen. Such correlation could be used to confirm the origin of the 21 cm signal, as well as give information on the properties of the X-ray sources during the EoR. We find that the correlations are positive during the early stages of reionization when most of the hydrogen is neutral, while they become negative when the intergalactic medium gets highly ionized, with the transition from positive to negative depending on both the X-ray model and the scale under consideration. With {\tt SKA} as the reference instrument for the 21~cm experiment, the predicted S/N for such correlations is $<1$ if the corresponding X-ray survey is only able to resolve and remove X-ray sources with observed flux $>10^{-15}\,\rm erg\, cm^{-2} \, s^{-1}$, while the cumulative S/N from $l=1000$ to $10^{4}$ at $x_{\rm HI}=0.5$ is $\sim 5$ if sources with observed flux $>10^{-17}\,\rm erg\, cm^{-2} \, s^{-1}$ are detected.Comment: 9 pages, 8 figure

Scandinavian perspectives on plant gene technology: applications, policies and progress

Plant research and breeding has a long and successful history in the Scandinavian countries, Denmark, Finland, Norway and Sweden. Researchers in the region have been early in adopting plant gene technologies as they developed. This review gives a background, as well as discuss the current and future progress of plant gene technology in these four countries. Country-specific details of the regulation of genetically modified plants are described, as well as similarities and differences in the approach to regulation of novel genome-editing techniques. Also, the development of a sustainable bioeconomy may encompass the application of plant gene technology and we discuss whether or not this is reflected in current associated national strategies. In addition, country-specific information about the opinion of the public and other stakeholders on plant gene technology is presented, together with a country-wise political comparison and a discussion of the potential reciprocal influence between public opinion and the political process of policy development. The Scandinavian region is unique in several aspects, such as climate and certain agriculturally related regulations, and at the same time the region is vulnerable to changes in plant breeding investments due to the relatively small market sizes. It is therefore important to discuss the role and regulation of innovative solutions in Scandinavian plant research and breeding.Peer reviewe

Toward a simulation approach for alkene ring-closing metathesis : scope and limitations of a model for RCM

A published model for revealing solvent effects on the ring-closing metathesis (RCM) reaction of di-Et diallylmalonate 7 has been evaluated over a wider range of conditions, to assess its suitability for new applications. Unfortunately, the model is too flexible and the published rate consts. do not agree with exptl. studies in the literature. However, by fixing the values of important rate consts. and restricting the concn. ranges studied, useful conclusions can be drawn about the relative rates of RCM of different substrates, precatalyst concn. can be simulated accurately and the effect of precatalyst loading can be anticipated. Progress has also been made toward applying the model to precatalyst evaluation, but further modifications to the model are necessary to achieve much broader aims

Linac-LHC EP Collider Options

We describe various parameter scenarios for a ring-linac ep collider based on LHC and an independent electron linac. Luminosities between $10^{31}$ and $10^{33} cm^{-2}s^{-1}$ can be achieved with a s.c. linac, operated either in pulsed or in cw mode, with optional recirculation, at a total electric wallplug power of order 20 MW. Higher luminosities, of several $10^{33} cm^{-2}s^{-1}$ can be reached by investing more electric power or by energy recovery. Finally, merits of a linac-ring ep collider are discussed

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation.

BACKGROUND: Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA. The growing variety of tools for measuring genomic copy numbers, including various types of array-CGH, SNP arrays and high-throughput sequencing, calls for a coherent framework offering unified and consistent handling of single- and multi-track segmentation problems. In addition, there is a demand for highly computationally efficient segmentation algorithms, due to the emergence of very high density scans of copy number. RESULTS: A comprehensive Bioconductor package for copy number analysis is presented. The package offers a unified framework for single sample, multi-sample and multi-track segmentation and is based on statistically sound penalized least squares principles. Conditional on the number of breakpoints, the estimates are optimal in the least squares sense. A novel and computationally highly efficient algorithm is proposed that utilizes vector-based operations in R. Three case studies are presented. CONCLUSIONS: The R package copynumber is a software suite for segmentation of single- and multi-track copy number data using algorithms based on coherent least squares principles.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

The Large Hadron-Electron Collider (LHEC) at the LHC

Sub-atomic physics at the energy frontier probes the structure of the fundamental quanta of the Universe. The Large Hadron Collider (LHC) at CERN opens for the first time the ‘terascale’ (TeV energy scale) to experimental scrutiny, exposing the physics of the Universe at the subattometric (∼ 10−19 m, 10−10 as) scale. The LHC will also take the science of nuclear matter to hitherto unparalleled energy densities. The hadron beams, protons or ions, in the LHC underpin this horizon, and also offer new experimental possibilities at this energy scale. A Large Hadron electron Collider, LHeC, in which an electron (positron) beam of energy 60 to 140 GeV is in collision with one of the LHC hadron beams, makes possible terascale leptonhadron physics. The LHeC is presently being evaluated in the form of two options, ‘ring-ring’ and ‘linac-ring’, either of which operate simultaneously with pp or ion-ion collisions in other LHC interaction regions. Each option takes advantage of recent advances in radio-frequency, in linear acceleration, and in other associated technologies, to achieve ep luminosity as large as 1033 cm−2s−1

The state, civil society and social rights in contemporary Russia

peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=fjcs21peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=fjcs2

A Large Hadron Electron Collider at CERN

This document provides a brief overview of the recently published report on the design of the Large Hadron Electron Collider (LHeC), which comprises its physics programme, accelerator physics, technology and main detector concepts. The LHeC exploits and develops challenging, though principally existing, accelerator and detector technologies. This summary is complemented by brief illustrations of some of the highlights of the physics programme, which relies on a vastly extended kinematic range, luminosity and unprecedented precision in deep inelastic scattering. Illustrations are provided regarding high precision QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed to run synchronously with the LHC in the twenties and to achieve an integrated luminosity of O(100) fb$^{-1}$. It will become the cleanest high resolution microscope of mankind and will substantially extend as well as complement the investigation of the physics of the TeV energy scale, which has been enabled by the LHC

A formally verified compiler back-end

This article describes the development and formal verification (proof of semantic preservation) of a compiler back-end from Cminor (a simple imperative intermediate language) to PowerPC assembly code, using the Coq proof assistant both for programming the compiler and for proving its correctness. Such a verified compiler is useful in the context of formal methods applied to the certification of critical software: the verification of the compiler guarantees that the safety properties proved on the source code hold for the executable compiled code as well

Cross-correlation between the 21-cm signal and [OIII] emitters during early cosmic reionization

We study statistics of the 21-cm signal from the epoch of reionization. We propose to use [OIII] line emitting galaxies to cross-correlate with the 21-cm signal from $z = 7 - 10$. To this aim, we employ simulations of reionization obtained post-processing the high-resolution cosmological hydrodynamic simulation Massive Black-II with the three-dimensional (3D) radiative transfer code CRASH to follow the propagation of ionizing photons from a variety of sources. We show that, during the early phases of reionization, the 21-cm signal is positively correlated with the spatial distribution of the [OIII] emitters on large scales $(k < 1h~\rm cMpc^{-1})$. This positive correlation is generated by the temperature-galaxy correlation and it is a few times larger than when we assume that the heating is saturated. As the reionized regions expand, the correlation changes its sign to negative from $z = 10$ to 8. The signals at this epoch can be detected by combining the Square Kilometre Array (SKA) and a wide-field [OIII] emitter survey. We also calculate the cross-power spectrum with a 3D [OIII] intensity field, aiming at exploiting future intensity mapping observations. We conclude that high-redshift [OIII] line emitters can be used to probe the reionization process when the intergalactic medium is largely neutral.Comment: 7 pages, 5 figures, published in MNRA