420 research outputs found

    Remote sensing-based actual evapotranspiration assessment in a data-scarce area of Brazil : a case study of the Urucuia Aquifer System

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    The large groundwater reserves of the Urucuia Aquifer System (UAS) enabled agricultural development and economic growth in the western Bahia State, in northeastern Brazil. Over the last several years, concern has grown around the aquifer’s diminishing water levels, and water balance (WB) studies are in demand. Considering the lack of measured actual evapotranspiration (ETa), a major component of the water cycle, this work uses the Operational Simplified Surface Energy Balance (SSEBop) model to estimate ETa, and compares it to basin-scale estimates from the Soil Moisture Accounting Procedure (SMAP) monthly model and from an annual WB closure method, based on gridded meteorological data and the Gravity Recovery and Climate Experiment (GRACE) product. Additionally, a comparative assessment of different versions of the SSEBop parameterization was per-formed. Moderate Resolution Imaging Spectroradiometer (MODIS) imagery was used to implement eight different versions of the SSEBop algorithm over the UAS between 2000 and 2013. SSEBop and SMAP ETa yielded similar seasonal patterns, with correlation coefficient (r) up to 0.65, mean difference (MD) of 0.8 mm/month and mean absolute difference (MAD) of 18.5 mm/month. Comparison of SSEBop annual ETa estimates to annual SMAP and WB closure estimates yielded low MD (12.1 and 7.3 mm/year, respectively) and MAD (82.5 and 82.8 mm/year, respectively), but also low r values (0.00 and 0.37, respectively). The comparison of the different SSEBop versions indicated the need to incorporate a calibration step of the aerodynamic heat resistance (rah) parameter. SSEBop results were also used for land cover and drought monitoring. Analysis indicates that agri-culture, associated with an increasing trend of atmospheric evaporative demand, is responsible for the decrease in groundwater levels and streamflow in the studied time period

    Pandemic detention: life with COVID-19 behind bars in Maryland

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    BackgroundPeople incarcerated during the COVID-19 pandemic face higher vulnerability to infection due to structural and social factors in carceral settings. Additionally, due to the higher prevalence of chronic health conditions among carceral populations, they are also at risk for more severe COVID-19 disease. This study was designed to explore the experiences of people incarcerated in prisons and jails in Maryland during the height of the pandemic.MethodsWe conducted semi-structured phone interviews between January 2021 and April 2022 with ten individuals incarcerated in Maryland carceral facilities during the height of the U.S. COVID-19 pandemic and were subsequently released from prison or jail. We transcribed the interviews, coded them, and engaged in content analysis, an inductive analytical approach to developing themes and meaning from qualitative data.ResultsFour themes emerged from participants’ descriptions of their experiences: (1) distress from fear, vulnerability, and lack of knowledge about COVID-19 and how to protect themselves, (2) shortcomings of prison and jail administrators and other personnel through lack of transparency and arbitrary and punitive enforcement of COVID-19 protocols, (3) lack of access to programming and communication with others, and (4) absence of preparation for release and access to usual re-entry services.ConclusionParticipants responded that the prison and jails’ response during the COVID-19 pandemic was ill-prepared, inconsistent, and without appropriate measures to mitigate restrictions on liberty and prepare them for release. The lack of information sharing amplified their sense of fear and vulnerability unique to their incarceration status. Study findings have several institutional implications, such as requiring carceral facilities to establish public health preparedness procedures and making plans publicly available

    Archaeological memory and urban morphology: the republican model in the imperial E42

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    The idea that the modern city should rise on a tabula rasa of the ancient city has been promoted since the Plan Voisin (Lecorbusier, 1925), and was essentially conceived on the ideology of the destruction of the ancienne regime, or to better say the destruction of its space, as a base to build a new world. Nowadays we recognize that demolitions of urban fabric inside historical cities are not conceivable, they were accomplished mostly by absolutist regimes or war bombings, upholding in substance the very same effect. Therefore we should reconsider critically the foundation of the E42 in Rome (1941), shown by fascist propaganda as a modern foundation, but planned outside the city centre. Even though meaningful demolitions were accomplished inside the monumental area of the Roman forums in the ‘30, in a very subtle manner, the archaeological topography of the ancient republican Rome became part of the new E42. The foundation was based on analogous orientations, in relationship with the foundation day of ancient Rome. Form and meaning of architectures, recalling the memory urban parts of ancient Rome, were used as archetypes to symbolize the past glory of Rome. This study presents the comparative analysis of the Palace of Receptions and Congresses (Adalberto Libera, 1938) and of the Temple of Venus and Rome (Hadrian, 121 ad), analyzing the city through models, proposing a new interpretation of the E42 as an analogous city. This comparative analysis recognizes in the plan elements of non-immediate perception, tracing a key to understand the meaning of the spaces of the city.Publisher versio

    Chapter X: The Tour de France: a success story in spite of competitive imbalance and doping

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    International audienceThe chapter goes as follows. In the first section it is demonstrated how the Tour de France is a high quality product. This is a result from its accurate design, its management, its economic model and its finance structure, both in comparison to other mega-sporting events and with reference to tournament theory. It is not easy to assess the competitive balance in the Tour de France since, as was demonstrated in chapter 10, it is at the same time an individual and a team sport contest. After reviewing some results published in literature so far, a new metrics for evaluating competitive balanced in the Tour de France is presented in section 2. Finally, the Tour de France cannot ignore doping as a potential threat to fan attendance and TV viewing. We therefore discuss the issue of doping and a new procedure to deal with doping in section 3

    Triose Phosphate Isomerase Deficiency Is Caused by Altered Dimerization–Not Catalytic Inactivity–of the Mutant Enzymes

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    Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI. A drastic decrease in TPI activity and an increased level of its substrate, dihydroxyacetone phosphate, have been measured in unpurified cell extracts of affected individuals. These observations allowed concluding that the different mutations in the TPI alleles result in catalytically inactive enzymes. However, despite a high occurrence of TPI null alleles within several human populations, the frequency of this disorder is exceptionally rare. In order to address this apparent discrepancy, we generated a yeast model allowing us to perform comparative in vivo analyses of the enzymatic and functional properties of the different enzyme variants. We discovered that the majority of these variants exhibit no reduced catalytic activity per se. Instead, we observed, the dimerization behavior of TPI is influenced by the particular mutations investigated, and by the use of a potential alternative translation initiation site in the TPI gene. Additionally, we demonstrated that the overexpression of the most frequent TPI variant, Glu104Asp, which displays altered dimerization features, results in diminished endogenous TPI levels in mammalian cells. Thus, our results reveal that enzyme deregulation attributable to aberrant dimerization of TPI, rather than direct catalytic inactivation of the enzyme, underlies the pathogenesis of TPI deficiency. Finally, we discovered that yeast cells expressing a TPI variant exhibiting reduced catalytic activity are more resistant against oxidative stress caused by the thiol-oxidizing reagent diamide. This observed advantage might serve to explain the high allelic frequency of TPI null alleles detected among human populations

    Dabigatran in patients with atrial fibrillation: perioperative and periinterventional management

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    In any type of invasive surgery, the patient’s individual risk of thromboembolism has to be weighed against the risk of bleeding. Based on various everyday situations in clinical routine, the purpose of the present expert recommendations is to provide appropriate perioperative and periinterventional management for patients with atrial fibrillation undergoing long-term treatment with the thrombin inhibitor dabigatran. As we currently have no routine laboratory test to measure therapeutic levels of the substance or the risk of bleeding, general measures such as a standardized documentation of the patient’s history, a sufficient time interval between the last preoperative dose and the procedure, and careful control of local hemostasis should be given special attention

    Ancient DNA Elucidates the Controversy about the Flightless Island Hens (Gallinula sp.) of Tristan da Cunha

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    A persistent controversy surrounds the flightless island hen of Tristan da Cunha, Gallinula nesiotis. Some believe that it became extinct by the end of the 19th century. Others suppose that it still inhabits Tristan. There is no consensus about Gallinula comeri, the name introduced for the flightless moorhen from the nearby island of Gough. On the basis of DNA sequencing of both recently collected and historical material, we conclude that G. nesiotis and G. comeri are different taxa, that G. nesiotis indeed became extinct, and that G. comeri now inhabits both islands. This study confirms that among gallinules seemingly radical adaptations (such as the loss of flight) can readily evolve in parallel on different islands, while conspicuous changes in other morphological characters fail to occur
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