10 research outputs found
Trastorno por déficit de atención e hiperactividad en educación primaria
In the present Final Degree Project in theoretical review format, it is intended to have a
greater knowledge about attention deficit hyperactivity disorder (ADHD). To this end, an
approach to this disorder has been carried out, in which different aspects are developed such as:
the concept of attention deficit hyperactivity disorder, problems that this disorder poses in the
educational field and the proposals and / or improvements that can be made in the classroom.
It also aims to deepen the disorder mentioned above and present the historical background that
has led to talk today of attention deficit hyperactivity disorder.En el presente Trabajo de Final de Grado en formato revisión teórica, se pretende tener
un mayor conocimiento sobre el trastorno por déficit de atención e hiperactividad (TDAH).
Para ello, se ha llevado a cabo un planteamiento sobre dicho trastorno, en el cual se desarrollan
diferentes aspectos como son: el concepto de trastorno por déficit de atención e hiperactividad,
problemas que este trastorno plantea en el ámbito educativo y las propuestas y/o mejoras que
se pueden aportar en el aula. Además, tiene como objetivo profundizar en el trastorno
mencionado anteriormente y presentará los antecedentes históricos que han llevado a que hoy
se hable de trastorno por déficit de atención e hiperactividad
Physico-chemical, biological and geological study of an underwater volcano in a degassing stage: Island of El Hierro
El objetivo principal del proyecto “Physico-chemical, biological and geological study of an underwater volcano in a degassing stage: Island of El Hierro”, (VULCANO-II) es estudiar, desde un punto de vista totalmente interdisciplinar, la fase de desgasificación activa del único volcán submarino monitoreado desde su nacimiento en aguas españolas. De esta forma, se pretende además, dar continuidad a los estudios multidisciplinares realizados sobre el volcán submarino de la isla de El Hierro en el contexto del proyecto del Plan Nacional VULCANO-I, (CTM2012-36317) y VULCANA (Vulcanología Canaria Submarina, IEO).
Para ello, se realizará la monitorización de las propiedades físico-químicas, biológicas y geológicas del proceso eruptivo submarino de la isla de El Hierro y otros puntos sensibles, como el volcán de Enmedio entre Gran Canaria y Tenerif
The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients
Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation
Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort
Background Acute respiratory distress syndrome (ARDS) can be classified into sub-phenotypes according to different inflammatory/clinical status. Prognostic enrichment was achieved by grouping patients into hypoinflammatory or hyperinflammatory sub-phenotypes, even though the time of analysis may change the classification according to treatment response or disease evolution. We aimed to evaluate when patients can be clustered in more than 1 group, and how they may change the clustering of patients using data of baseline or day 3, and the prognosis of patients according to their evolution by changing or not the cluster.Methods Multicenter, observational prospective, and retrospective study of patients admitted due to ARDS related to COVID-19 infection in Spain. Patients were grouped according to a clustering mixed-type data algorithm (k-prototypes) using continuous and categorical readily available variables at baseline and day 3.Results Of 6205 patients, 3743 (60%) were included in the study. According to silhouette analysis, patients were grouped in two clusters. At baseline, 1402 (37%) patients were included in cluster 1 and 2341(63%) in cluster 2. On day 3, 1557(42%) patients were included in cluster 1 and 2086 (57%) in cluster 2. The patients included in cluster 2 were older and more frequently hypertensive and had a higher prevalence of shock, organ dysfunction, inflammatory biomarkers, and worst respiratory indexes at both time points. The 90-day mortality was higher in cluster 2 at both clustering processes (43.8% [n = 1025] versus 27.3% [n = 383] at baseline, and 49% [n = 1023] versus 20.6% [n = 321] on day 3). Four hundred and fifty-eight (33%) patients clustered in the first group were clustered in the second group on day 3. In contrast, 638 (27%) patients clustered in the second group were clustered in the first group on day 3.Conclusions During the first days, patients can be clustered into two groups and the process of clustering patients may change as they continue to evolve. This means that despite a vast majority of patients remaining in the same cluster, a minority reaching 33% of patients analyzed may be re-categorized into different clusters based on their progress. Such changes can significantly impact their prognosis
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)
Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters.
Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs).
Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001).
Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio
Estudio del crecimiento en cianobacterias a nivel unicelular
Trabajo presentado en el II Basque Microbiology Meeting MikrobioGUNE, celebrado en Bilbao (España) el 13 de diciembre de 2022
Human zygote morphological indicators of higher rate of arrest at the first cleavage stage
Cáceres ciudad cultural Impressionniste
Convocatoria Proyectos de innovación de Extremadura 2018/2019Se presenta un proyecto surgido a iniciativa del IES El Brocense de Cáceres y llevado a cabo entre varios centros extremeños que tiene como eje temático el Impresionismo. Se trabajó esta corriente artística en distintas materias del currículo y se expusieron los resultados en una exposición en la Plaza Mayor de Cáceres y en la biblioteca del centro. Los principales objetivos del proyecto fueron: consolidar el trabajo multidisciplinar y cooperativo entre el profesorado y el alumnado de los centros participantes; crear una conciencia social sobre la importancia del francés en la cultura general y en la formación de la civilización europea; acercar la educación a los ciudadanos; promover el uso de las TIC y de las lenguas extranjeras (francés, inglés y portugués); mejorar el espíritu emprendedor, creativo y colaborativo de los alumnos; mejorar la sociedad respetando el medio ambiente, el ser humano y su naturaleza e incentivar la pedagogía activa y eficaz que desarrolle las competencias clave o profesionalesExtremaduraES
La expresión oral y escrita, objetivo fundamental de calidad de la enseñanza
Convocatoria de Proyectos de innovación de Extremadura 2017/2018Se describe un proyecto llevado a cabo en el IES Miguel Durán (Azuaga, Badajoz) desarrollado dentro del Sistema de Gestión de Calidad del centro, que tenía como objetivo principal que los alumnos adquirieran las competencias necesarias para una correcta expresión oral y escrita (mejora de la competencia informacional y las competencias comunicativa e idiomática). Para conseguir el objetivo se organizaron distintas actividades promovidas por el Grupo de Trabajo de la Biblioteca del centro: fomento de la lectura, feria del libro, Día de la poesía, diversas actividades de lectura en la biblioteca, club de lectura con libros digitales, etc., así como la realización de otras actividades y la elaboración de materiales por parte de los distintos departamentos del instituto como: exposiciones de los alumnos ante el aula, lectura en distintos soportes, realización de trabajos de investigación, actividades de enriquecimiento del vocabulario, etc.ExtremaduraES