Resposta do tomate cereja à adubação organomineral para incremento na produtividade

In tomato cultivation, the need to optimize production due to the high demand for nutrients and cultural treatments is notorious. Given this demand for organomineral, as a technological alternative for plant nutrition and production. Thus, the presented evaluate the plant growth, production and plant growth, the growth of the cherry tomato crop- Being different dosages of the organization of work - Being different in the percentages of 40% percentages; 80%; 160% and 320% and a mineral treatment (NPK both), provided according to the needs of the culture. Tomatoes, presence of plant growth, dry matter composition and root system, photometrics and plant productivity, floral cluster photograms, fruit weight and shelf life of cherry cherry. Observing that the offer of the organomineral to the culture, it was obtained as the best averages for the treatment in the proportion of tomato of 40% in the plant growth, physiological aspects and for the shelf life. Results, for the productivity values, the treatment with organomineral 80% obtained better results than the other treatments. In the natural curvature of yield 3 for variable yield for variable yield, it is determined as the ideal dose of 19% of the recommended dose of NPK fruit fertilization. The tomato has high demand, and the results found elucidate the nutrition with organomineral, especially at doses of 40% and 80% of the recommended fertilization, that the tomato plant absorbs nutrients more efficiently, favoring the growth of the crop, tomato productivity and the post-harvest quality.Na cultura do tomate é notório a necessidade de otimização da produção pela alta demanda de nutrientes e tratos culturais. Atendendo esta demanda, surge o organomineral como alternativa tecnológica para a nutrição e a produção de plantas. Sendo assim, o estudo avaliou o crescimento da planta, a produção e o pós-colheita do tomate cereja submetido a diferentes dosagens de organomineral peletizado, nas porcentagens de 0%, 40%; 80%; 160% e 320% e um tratamento mineral (NPK), ambos fornecidos conforme a necessidade da cultura. Avaliou-se variáveis de crescimento das plantas, acúmulo de matéria seca da parte aérea e sistema radicular, variáveis fisiológicas e produtividade das plantas, presença de cacho floral, peso dos frutos e tempo de prateleira de tomate cereja. Observou-se que a oferta do organomineral à cultura do tomate, obteve-se as melhores médias para o tratamento na proporção de 40% no crescimento da planta, aspectos fisiológicos e para o tempo de prateleira. Contudo, para os valores de produtividade, o tratamento com organomineral 80% obtiveram resultados superiores aos demais tratamentos. Na curva característica de regressão para as doses de organomineral para a variável produtividade, determinou-se como dose ideal o percentual de 193% da dose recomendada de adubação NPK para produção de frutos. O tomateiro apresenta alta exigência nutricional, e os resultados encontrados elucidam que a nutrição com organomineral, principalmente nas doses de 40% e 80% da adubação recomendada, permite que o tomateiro absorva os nutrientes de forma mais eficiente, favorecendo o crescimento da cultura, a produtividade e a qualidade pós-colheita

Zumbido e intolerância a sons : evidência e experiência de um grupo brasileiro

Introdução Zumbido e intolerância a sons são queixas frequentes e subjetivas que podem ter impacto na qualidade de vida do paciente. Objetivo Apresentar uma revisão dos principais pontos, inclusive conceitos, fisiopatologia, diagnóstico e abordagem do paciente com zumbido e sensibilidade a sons. Método Revisão da literatura com levantamento bibliográfico na base de dados da LILACS, SciELO, Pubmed e MEDLINE. Foram selecionados artigos e capítulos de livros sobre zumbido e sensibilidade a sons. Os diversos tópicos foram discutidos por um grupo de profissionais brasileiros e as conclusões, descritas. Resultado A prevalência de zumbido tem aumentado ao longo dos anos, muitas vezes associado a perda auditiva, fatores metabólicos e erros alimentares. A avaliação médica deve ser feita minuciosamente no sentido de orientar a solicitação de exames subsidiários. Os tratamentos disponíveis atualmente variam de medicamentos ao uso de sons com características específicas e técnicas de meditação, com resultados variáveis. Conclusão Foi apresentada uma revisão sobre os temas que permitindo ao leitor uma visão ampla da abordagem dos pacientes com zumbido e sensibilidade auditiva baseada em evidências científicas e experiência nacional.Introduction Tinnitus and sound intolerance are frequent and subjective complaints that may have an impact on a patient's quality of life. Objective To present a review of the salient points including concepts, pathophysiology, diagnosis and approach of the patient with tinnitus and sensitivity to sounds. Methods Literature review with bibliographic survey in LILACS, SciELO, Pubmed and MEDLINE database. Articles and book chapters on tinnitus and sound sensitivity were selected. The several topics were discussed by a group of Brazilian professionals and the conclusions were described. Results The prevalence of tinnitus has increased over the years, often associated with hearing loss, metabolic factors and inadequate diet. Medical evaluation should be performed carefully to guide the request of subsidiary exams. Currently available treatments range from medications to the use of sounds with specific characteristics and meditation techniques, with variable results. Conclusion A review on tinnitus and auditory sensitivity was presented, allowing the reader a broad view of the approach to these patients, based on scientific evidence and national experience

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation

<div><p>In this study, our aims were to investigate transient receptor potential melastatin-8 channels (TRPM8) involvement in rotundifolone induced relaxation in the mesenteric artery and to increase the understanding of the role of these thermosensitive TRP channels in vascular tissue. Thus, message and protein levels of TRPM8 were measured by semi-quantitative PCR and western blotting in superior mesenteric arteries from 12 week-old Spague-Dawley (SD) rats. Isometric tension recordings evaluated the relaxant response in mesenteric rings were also performed. Additionally, the intracellular Ca²⁺ changes in mesenteric artery myocytes were measured using confocal microscopy. Using PCR and western blotting, both TRPM8 channel mRNA and protein expression was measured in SD rat mesenteric artery. Rotundifolone and menthol induced relaxation in the isolated superior mesenteric artery from SD rats and improved the relaxant response induced by cool temperatures. Also, this monoterpene induced an increase in transient intracellular Ca²⁺. These responses were significantly attenuated by pretreatment with capsazepine or BCTC, both TRPM8 channels blockers. The response induced by rotundifolone was not significantly attenuated by ruthenium red, a non-selective TRP channels blocker, or following capsaicin-mediated desensitization of TRPV1. Our findings suggest that rotundifolone induces relaxation by activating TRPM8 channels in rat superior mesenteric artery, more selectively than menthol, the classic TRPM8 agonist, and TRPM8 channels participates in vasodilatory pathways in isolated rat mesenteric arteries.</p></div

Vasorelaxation induced by rotundifolone and menthol in rat mesenteric arteries submitted to cold temperatures involves TRPM8 activation.

<p>Bar graph summary shows vasodilatation induced by (A) rotundifolone (3x10^-3 M, n = 6) or (B) menthol (10⁻³ M, n = 6) in rat mesenteric arteries without vascular endothelium submitted to cold temperatures, was abolished in the presence of BCTC (2x10^-6 M). Neither ruthenium red (10⁻⁵ M) nor capsaicin-evoked desensitization (10⁻⁵ M) of TRPV1 channels modified the relaxation induced by menthol or rotundifolone. Data are presented as the mean ± SEM. The data were examined using one-way ANOVA followed by the Bonferroni post-test. *p<0.05, **p<0.01 and ***p<0.001 vs control; #p< 0.05 and ###p<0.001 vs rotundifolone or menthol.</p

Rotundifolone and the cooling compound menthol enhanced the vasorelaxation effect induced by cold temperatures in rat mesenteric arteries by increasing calcium influx.

<p>Bar graph summary showing that the response induced by 3x10-3 M rotundifolone (A) or 10–3 M menthol (B) (n = 6) in the vasodilatation induced by cold temperatures in rat superior mesenteric arteries rings without vascular endothelium was attenuated in the presence of EGTA. Data are the mean ± SEM. The data were examined using one-way ANOVA followed by the Bonferroni post-test. *p < 0.05; **p < 0.01 and ***p < 0.001 rotundifolone or menthol vs control; ###p < 0.001 vs rotundifolone or menthol.</p

TRPM8 channels are present in rat superior mesenteric artery.

<p>(A) TRPM8 mRNA expression by semi-quantitative PCR in superior mesenteric artery with endothelium removed (n = 3). C, control; P1, 1 μL prostate RT reaction; P2, 2 μL prostate RT reaction, Me, 2 μL mesenteric artery RT reaction. (B) Western blot analysis of TRPM8 protein expression in rat vascular tissue. Molecular weight of TRPM8 was 125 KDa. Bottom panel: β actin used to demonstrate protein loading (at 42kDa).</p

Rotundifolone and the cooling compound menthol enhanced the vasorelaxation effect induced by cold temperatures in mesenteric arteries.

<p>Bar graph summary showing that old temperature-induced vasodilatation is increased in the presence of rotundifolone (A) or menthol (3x10-4 M, 10–3 M and 3x10-3 M; n = 6) (B) in rat superior mesenteric arteries rings without vascular endothelium. Data are the mean ± SEM. The data were examined using one-way ANOVA followed by the Bonferroni post-test. *p < 0.05 and ***p < 0.001 rotundifolone or menthol vs control.</p