42 research outputs found
Asian financial development: the rise of a new financial system
Today, the global financial system is inefficient in bridging the gap between the developed and developing countries. The dynamically developing countries, such as Asian states, are not satisfied with modern international financial institutions and are actively involved in regional integration, creating new international financial institutions. The newly formed financial institutions contribute to the formation of a different system of financial relations in Asia, which, in turn, is being transformed into the Asian financial system. These trends cannot avoid the impact of the global imbalances. The object of the article is to prove the efficiency of the Asian financial institutions in fighting global imbalances in the region. The major task of these institutions is not the substitution of the current global mechanisms, but their assistance and helping them in solving the global problems on the regional level. The major results include the proof that the developing economies in Asia are more consolidated and capable of conducting a single economic strategy in the long run and the proof of the higher efficiency of Asian financial institutions and their single geo-economic strategy in the long run; this suggests that a new Asian financial system is being built
Implementation Principles of the Religious Component in the Russian Educational System: Approaches and Solutions
An active discussion of the questions of the advisability of forming new principles of national unity and creating an orderly harmonious world in the minds of people, strengthening the educational functions of the state, its concern for public morality do not primarily concern education, humanization of its content, and revision of the educational process. The formation and implementation of a state policy adequate to this problem must comply with the requirements of our time, create, on the one hand, conditions for ensuring the rights and freedoms of citizens, including the observance of the fundamental principles of religious freedom, and on the other, develop legislative norms that regulate these rights. A legal democratic state provides for the formation of public policy in accordance with the needs of society and taking into account public thought. The secular nature of public education is not an obstacle to the introduction of disciplines in the provision of religious knowledge in the educational process of schools, religious knowledge can and should be considered as an element of secular culture. Knowledge of religion should be carried out by secular teachers, be neutral in content and not be accompanied by religious rites. The problems of the formation of moral and spiritual values, the worldview of a person, the introduction of religious disciplines in secondary schools are vividly discussed in scientific, educational, government circles, as well as among representatives of the clergy. The religious component in secular education will give importance to folk culture and traditional religion, which will form concepts such as tolerance and respect for other faiths and cultures, which is important in the context of globalization of the world
Intelligent control system of metal vacuum sputtering process on the basis of application of multi-agent system
A vacuum sputtering process comprises evaporation of the material and subsequent vapor condensation on the substrates. Getting required and repeatable quality of coatings is challenging task. It depends on capabilities of equipment, type of evaporator, interaction evaporator with the evaporating substance and deposition process. Sputtering process parameters are determined by the ability evaporator to maintain a certain temperature evaporated substance for a long time. Controlling operations sequence of pumping and heating depends on achieving optimum vacuum conditions, in spite of used pumping method. The control system must foresee and identify emerging cracks or damage of the system components. This paper focuses on the development of intelligent control system vacuum process on the agent-based approach. © IDOSI Publications, 2013
Pedagogical Conditions of Formation Professional Competences of the Bachelor-Economist on the Basis of Understanding
The article describes the issues of professional training of bachelors of Economics in the modern University as a specific educational system. The work clarifies the specificity of professional activity of future bachelors of Economics as subjects of study. The article simulated the educational process as organized in the module-rating system of education in the modern University, developed a conceptual and technological models that determine our understanding of the nature of the content, technologies of formation of professionally significant competences of future bachelors of economy in the modern University. Besides, in the article the organizational-pedagogical conditions providing efficiency of realization of the model are formulated
Pedagogical Conditions of Formation Professional Competences of the Bachelor-Economist on the Basis of Understanding
The article describes the issues of professional training of bachelors of Economics in the modern University as a specific educational system. The work clarifies the specificity of professional activity of future bachelors of Economics as subjects of study. The article simulated the educational process as organized in the module-rating system of education in the modern University, developed a conceptual and technological models that determine our understanding of the nature of the content, technologies of formation of professionally significant competences of future bachelors of economy in the modern University. Besides, in the article the organizational-pedagogical conditions providing efficiency of realization of the model are formulated
High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica
Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome. Several reports have demonstrated a severe alteration in lipoprotein metabolism. However, little is known about changes in circulating lipids in NE. The objectives of this study were to evaluate changes in serum total cholesterol, high density cholesterol (HDCL), and triglycerides. In addition to evaluation of serum cytokine activation associations, changes in lipid profile and cytokine activation were determined for gender, thrombocyte counts, and VEGF. Elevated levels of triglycerides and decreased HDCL were observed in NE, while total cholesterol did not differ from controls. High triglycerides were associated with both the lowest thrombocyte counts and high serum VEGF, as well as a high severity score. Additionally, there were higher levels of triglycerides in male than female NE patients. Low triglycerides were associated with upregulation of IFN-γ and IL-12, suggesting activation of Th1 helper cells. Furthermore, levels of IFN-γ and IL-12 were increased in patients with lower severity scores, suggesting that a Th1 type immune response is playing protective role in NE. These combined data advance the understanding of NE pathogenesis and indicate a role for high triglycerides in disease severity
One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults
Several studies have shown that the prevalence of migraine and tension-type headache (TTH) varied between different geographical regions. Therefore, there is a need of a nationwide prevalence study for headache in our country, located between Asia and Europe. This nationwide study was designed to estimate the 1-year prevalence of migraine and TTH and analyse the clinical features, the impact as well as the demographic and socio-economic characteristics of the participant households in Turkey. We planned to investigate 6,000 representative households in 21 cities of Turkey; and a total of 5,323 households (response rate of 89%) aged between 18 and 65 years were examined for headache by 33 trained physicians at home on the basis of the diagnostic criteria of the second edition of the International Classification of Headache Disorders (ICHD-II). The electronically registered questionnaire was based on the headache features, the associated symptoms, demographic and socio-economic situation and history. Of 5,323 participants (48.8% women; mean age 35.9 ± 12 years) 44.6% reported recurrent headaches during the last 1 year and 871 were diagnosed with migraine at a prevalence rate of 16.4% (8.5% in men and 24.6% in women), whereas only 270 were diagnosed with TTH at a prevalence rate of 5.1% (5.7% in men and 4.5% in women). The 1-year prevalence of probable migraine was 12.4% and probable TTH was 9.5% additionally. The rate of migraine with aura among migraineurs was 21.5%. The prevalence of migraine was highest among 35–40-year-old women while there were no differences in age groups among men and in TTH overall. More than 2/3 of migraineurs had ever consulted a physician whereas only 1/3 of patients with TTH had ever consulted a physician. For women, the migraine prevalence was higher among the ones with a lower income, while among men, it did not show any change by income. Migraine prevalence was lower in those with a lower educational status compared to those with a high educational status. Chronic daily headache was present in 3.3% and the prevalence of medication overuse headache was 2.1% in our population. There was an important impact of migraine with a monthly frequency of 5.9 ± 6, and an attack duration of 35.1 ± 72 h, but only 4.9% were on prophylactic treatment. The one-year prevalence of migraine estimated as 16.4% was similar or even higher than world-wide reported migraine prevalence figures and identical to a previous nation-wide study conducted in 1998, whereas the TTH prevalence was much lower using the same methodology with the ICHD-II criteria
NPY Neuron-Specific Y2 Receptors Regulate Adipose Tissue and Trabecular Bone but Not Cortical Bone Homeostasis in Mice
BACKGROUND: Y2 receptor signalling is known to be important in neuropeptide Y (NPY)-mediated effects on energy homeostasis and bone physiology. Y2 receptors are located post-synaptically as well as acting as auto receptors on NPY-expressing neurons, and the different roles of these two populations of Y2 receptors in the regulation of energy homeostasis and body composition are unclear. METHODOLOGY/PRINCIPAL FINDINGS: We thus generated two conditional knockout mouse models, Y2(lox/lox) and NPYCre/+;Y2(lox/lox), in which Y2 receptors can be selectively ablated either in the hypothalamus or specifically in hypothalamic NPY-producing neurons of adult mice. Specific deletion of hypothalamic Y2 receptors increases food intake and body weight compared to controls. Importantly, specific ablation of hypothalamic Y2 receptors on NPY-containing neurons results in a significantly greater adiposity in female but not male mice, accompanied by increased hepatic triglyceride levels, decreased expression of liver carnitine palmitoyltransferase (CPT1) and increased expression of muscle phosphorylated acetyl-CoA carboxylase (ACC). While food intake, body weight, femur length, bone mineral content, density and cortical bone volume and thickness are not significantly altered, trabecular bone volume and number were significantly increased by hypothalamic Y2 deletion on NPY-expressing neurons. Interestingly, in situ hybridisation reveals increased NPY and decreased proopiomelanocortin (POMC) mRNA expression in the arcuate nucleus of mice with hypothalamus-specific deletion of Y2 receptors in NPY neurons, consistent with a negative feedback mechanism between NPY expression and Y2 receptors on NPY-ergic neurons. CONCLUSIONS/SIGNIFICANCE: Taken together these data demonstrate the anti-obesogenic role of Y2 receptors in the brain, notably on NPY-ergic neurons, possibly via inhibition of NPY neurons and concomitant stimulation of POMC-expressing neurons in the arcuate nucleus of the hypothalamus, reducing lipogenic pathways in liver and/or skeletal muscle in females. These data also reveal as an anti-osteogenic effect of Y2 receptors on hypothalamic NPY-expressing neurons on trabecular but not on cortical bone