Политика образования в Сирии: обзор

В статье рассматриваются особенности системы образования в Сирии, политики, формирующей этапы учебного процесса и основные характеристики иерархической структуры сирийского образования.This paper provides an insight to the educational system in Syria, the politics that shape the phases of educational process and the main characteristics of Syrian hierarchical structure of education

Direct Sheet Molding Compound process (D-SMC)

The combination of highly crosslinked resin and long glass fiber reinforcement in direct sheet molding compound (D-SMC) provides the parts with high physical properties and low density suitable for large interior and exterior automotive applications. Different stages of D-SMC process including maturation zone and compression molding are studied using mathematical analysis, numerical simulation and experimental investigations. An analytical analysis is used to calculate the pressure and velocity in the first section of maturation zone and then the permeability of fiber bundle is calculated by simulation and the agreement between the available empirical equation and simulation was obtained. The flow is simulated in the next section of maturation zone using Ansys CFX and it was found the interlocking chain belt plays an important role in impregnation of bundles with paste. The microstructure of fiber glass bundles in compression is investigated in a flat plaque mold. Analyses of the bundle deformation, including bending and deformation of the tow shape, are done for the charge and specific sites within a square plaque part for 30 percent and 62 percent of initial charge mold area coverages. Microscopy and micro-computed tomography (micro-CT) of the samples clarify the microstructure of the bundles after flow. The bundles at the part edge and corner deform more than the bundles close to center of the mold in both initial charge cases. The bundles flatten at all positions and bundle bending is mainly observed at the corner. The tow width changes and tow deflections are higher in the samples of 30 percent mold area coverage. The micro-CT images show that the bundles keep their cohesion and stay straight within the middle of the flow path position, but bend at the edge of the mold. Mold filling simulation using MoldflowTM (Autodesk) predict fiber tow orientation through the thickness using the reduced-strain closure (RSC) models for fiber distribution for 30 and 62 percent initial mold area coverage. The measured value of orientation from micro-CT images confirms the random orientation through the thickness, consistent with the RSC model. The Carreau viscosity model explains the behaviour of the D-SMC paste. Another viscosity model for suspensions of high volume of planar randomly oriented glass bundles defines the flow behaviour in the process and is used to simulate a flow field. An open source CFD software package of OpenFOAM solves the equation of mass and momentum along with the introduced viscosity model by the volume of fluid technique in the three dimensional system. The simulation results show the plug flow profile at all positions and times during the process. To study bundle movement and deformation during the process, it is assumed that regions of very high viscosity with the same dimension of bundles represent bundles at different positions of the mold. The results reveal that the bundles close to the edges and corners of the mold moved more than bundles in the middle and diagonal positions. Moreover, the velocity profile shows higher velocity at these locations. Experimentally, the red bundles are placed at different locations of the charge and track during the process. The calculated movement distances of the bundles at different locations from the experiment and the OpenFOAM simulation follow the same trends and therefore agree. In D-SMC, there is a viscosity variation through thickness because of temperature gradient and glass bundle volume fraction variation. The charge is placed between two hot plates of mold which are then closed to squeeze the charge and filled the mold. The layers of charge close to the hot mold plates act as lubricant for layers of charge in center. Because of greater resistance of charge in the center to flow, the hotter lubrication layer may flow preferentially before core layers of charge. The simulation is run using Ansys Polyflow to study the preferential flow in D-SMC process. Several stacks of charges on top of each other are used for compression molding. The flow is simulated for two charges to investigate the evolution of interface during mold filling Images of cross sections from experimental samples are used to validate the simulation analysis

Immobilization of cytochrome P450 BM3 from Bacillus megaterium on magnetic nanoparticles to develop an effective biocatalyst for hydroxylation reactions

Les catalyseurs chimiques sont utilisés dans différents procédés de synthèse. Cependant, la pollution qu'ils causent sur l'environnement n’est pas prise en considération. Les procédés de synthèse chimique nécessitent généralement un grand volume de solvants organiques, produisant d’énormes quantités de déchets chimiques, souvent toxiques et non dégradables. Le remplacement des catalyseurs chimiques par des biocatalyseurs (enzymes) pourrait donc bénéficier de leur nature écologique et de leur grande sélectivité envers les produits désirés. Néanmoins, la faible activité et stabilité des enzymes ainsi que leurs coûts élevés sont des obstacles majeurs au développement des systèmes enzymatiques. Par conséquent, des études axées sur le développement de systèmes biocatalytiques plus actifs, stables et rentables, pouvant ouvrir les portes vers un environnement plus vert, sont très souhaitables. Parmi les enzymes qui catalysent des réactions d’importance dans de nombreux procédés de synthèse, le cytochrome P450 BM3 issu de Bacillus megaterium fait l'objet de cette thèse. L'enzyme est capable d’hydroxyler les liaisons C–H des acides gras (C₁₂-C₂) à température ambiante et pH physiologique. Pour cette réaction, BM3 n'a besoin que d’oxygène et de deux électrons habituellement obtenus de son cofacteur naturel, le NADPH. Cependant, pour engager cette enzyme dans les réactions d'hydroxylation, quelques obstacles importants doivent être surmontés : (i) le cofacteur coûteux (NADPH), devrait être remplacé par une source d'électrons moins chère ou régénérée, (ii) la stabilité enzymatique devrait être améliorée et (iii) l'enzyme devrait être facilement récupérable du milieu de réaction pour être réutilisée. Dans ce contexte, cette étude propose pour la première fois l'immobilisation d'un BM3 sur des nanoparticules magnétiques (NMP) d’oxyde de fer. Ce système enzymatique bénéficie (i) de la préférence de l'enzyme pour les cofacteurs NADH et BNAH (moins chers que le NADPH), (ii) de la réutilisation facile du biocatalyseur et (iii) d’une stabilité significative de l’enzyme lors du stockage. Les NMP synthétisées ont été fonctionnalisées pour permettre l’immobilisation de l'enzyme par adsorption ou liaison covalente. Par conséquent, les BM3-NMP adsorbées / réticulées ou liées de façon covalente ont été obtenues en immobilisant P450 BM3 (R966D / W1046S) sur Ni²⁺-PMIDA-NMP ou sur des NMP activés par glutaraldéhyde, respectivement.L'activité de l’enzyme immobilisée a été comparée avec celle de l’enzyme libre dans la réaction d'hydroxylation du 10-pNCA comme substrat modèle. L'acide myristique a également été utilisé comme substrat modèle pour confirmer la capacité d’hydroxylation sélective de l’enzyme sur les atomes de carbone ω-1, -2 ou -3. Pour les mêmes conditions opératoires, le BM3 adsorbé / réticulé a montré plus de 85% de l'activité de l’enzyme libre, alors que pour les BM3-NMP liées de manière covalente cela représente 60%. La séparation facile des NMP du milieu réactionnel à l’aide d’un aimant a permis de réutiliser le système enzymatique cinq fois consécutives. Après 5 cycles de réaction, l'enzyme réticulée a conservé 100% de son activité initiale. Compte tenu que le recyclage de l’enzyme libre n’est pas faisable, ce résultat est d’une importance considérable dans les applications pratiques. De plus, la stabilité de l’enzyme pendant un mois de stockage à 4 ºC a été évaluée pour chaque système de BM3. Les résultats ont montré que l’enzyme libre n’était plus active après seulement une semaine de stockage dans ces conditions. L'enzyme réticulée n'a montré qu'une activité relative de 41% après un mois de stockage, mais pour le BM3 fixée de façon covalente, la valeur correspondante a été de 80%. La cinétique de l'hydroxylation du 10-pNCA en présence de l’enzyme libre ou immobilisée a été également étudiée. Sur la base des données expérimentales, un modèle de Hill (coefficient de Hill égal à 2) a été obtenu pour l'enzyme libre. Il a été démontré que les mêmes paramètres cinétiques sont capables de prédire le comportement du système BM3-adsorbé et BM3-réticulé dans la réaction d’hydroxylation, étant donné sa similarité avec celui de l’enzyme libre. En conclusion, les résultats de cette thèse ont montré qu'un système enzymatique actif, stable et rentable peut être obtenu en immobilisant le BM3 sur des NMP fonctionnalisées. Il bénéficie autant des avantages de l'enzyme que du support. Ainsi, l'immobilisation sur des NMP d’une enzyme spécialement conçue pour remplacer le couteux NADPH par des cofacteurs moins chers mais efficaces (NADH et BNAH) offre en même temps une amélioration significative de sa stabilité et facilite son recyclage.MNPs have been synthesized and surface functionalized to attach the enzyme via two different methods, adsorption and covalent binding. Moreover, glutaraldehyde was used to treat the adsorbed enzyme molecules on MNPs (crosslinking-adsorption). Therefore, adsorbed, crosslinked-adsorbed, or covalently bound BM3-MNPs were obtained by immobilizing P450 BM3 on synthesized Ni²⁺-functionalized MNPs or glutaraldehyde pre-activated MNPs, respectively. The immobilized enzyme activity was compared to its free counterpart in hydroxylation reaction of 10-pNCA (10-(4-Nitrophenoxy) decanoic acid) as a substrate model. Myristic acid was also used as a substrate model to confirm the enzyme selective hydroxylation at ω-1, -2, or -3 carbon positions. The effect of cofactor (NADH and its analogue, BNAH) on the enzyme activity was also investigated. The adsorbed/crosslinked-adsorbed BM3 showed more than 85% of the free enzyme activity while the covalently bound BM3-MNPs presented 60% of the free enzyme activity under the same reaction conditions. An important feature of BM3-MNPs system is the possibility of recycling the biocatalyst. Facile separation of the magnetic nanoparticles from the reaction medium by applying a magnet provided the opportunity of reusing the enzymatic system for five times. After 5 cycles of reaction, the crosslinked-adsorbed enzyme retained 100% of its initial activity. Although the covalently bound enzyme showed, only half of the crosslinked-adsorbed enzyme activity, its storage stability was more significant. Taking into account that the enzyme reuse is an essential concern in many large-scale applications and the free BM3 cannot be recovered and reused, this result is noteworthy. Storage stability tests revealed that the free enzyme became inactive after one-week while the crosslinked-adsorbed enzyme and the covalently attached BM3 on MNPs showed 41% and 80% relative activity after one month, respectively. Finally, the steady-state kinetics of 10-pNCA hydroxylation by free and immobilized BM3 was investigated. Based on the experimental data, a non-Michaelis-Menten, Hill model (Hill coefficient of 2) was obtained for the free enzyme which could also predict the adsorbed and crosslinked-adsorbed BM3-MNPs system performance. This sigmoidal behavior was found to be independent of enzyme concentration and type of cofactor. However, since the enzyme activity was only 60% of the free enzyme for covalently bound BM3, further studies are necessary for a better understanding of this system. In summary, the results of this thesis show that an active, stable, and cost-effective BM3-MNPs system can be obtained by immobilizing an engineered BM3 on functionalized MNPs. Such systems benefit from the advantages of both enzyme and support. An engineered enzyme can fulfill the desired targets including the replacement of costly NADPH by less-expensive, yet effective cofactors namely NADH and BNAH. Furthermore, immobilization of this enzyme on MNPs improves its stability and facilitates the recycling process.Chemical catalysts are used in different synthetic processes from lab to industrial scales. High reaction yields usually achieved by this type of processes favor their application in many industries without considering the pollution they cause to the environment. Chemical synthesis processes usually require a high volume of organic solvents and produce tons of chemical wastes which are often toxic and not degradable. Replacing conventional catalysts by biocatalysts (enzymes) can benefit from their environmentally friendly nature and high selectivity toward the desired products. Although the advantages of biocatalysts over chemical catalysts have been proven, the application of enzymes in an industrial level is still not considerable. The enzyme low activity, stability, and high cost are the main concerns in developing large-scale enzymatic systems. Therefore, in the context of a greener environment, studies focusing on the development of more active, stable, and cost-effective enzymatic systems are in great demand. Among several enzymes that can catalyze essential synthesis reactions, cytochrome P450 BM3 from Bacillus megaterium is the subject of this thesis. This enzyme hydroxylates the saturated and unsaturated C–H bonds of medium to long chain fatty acids at room temperature and physiological pH. For this reaction, BM3 only needs molecular oxygen and two electrons usually obtained from its natural cofactor, NADPH. However, to engage this enzyme in hydroxylation reactions, some important obstacles should be overcome: (i) the costly cofactor (NADPH) should be replaced by a cheaper source of electrons or regenerated, (ii) the enzyme stability should be improved, and (iii) the enzyme should be easily recovered from the reaction medium to be reused. In this context, this study proposes for the first time the immobilization of an optimized BM3 mutant on functionalized iron oxide magnetic nanoparticles (MNPs). This enzymatic system benefits from (i) the enzyme preference towards cofactors like the reasonably priced NADH and the very cheap BNAH, (ii) facile recovery and reuse of the biocatalyst (enzyme-MNPs), and (iii) the enzyme significant storage stability

Achievable Secrecy Rates of an Energy Harvesting Device with a Finite Battery

In this paper, we investigate the achievable secrecy rates in an Energy Harvesting communication system composed of one transmitter and multiple receivers. In particular, because of the energy constraints and the channel conditions, it is important to understand when a device should transmit or not and how much power should be used. We introduce the Optimal Secrecy Policy in several scenarios. We show that, if the receivers demand high secrecy rates, then it is not always possible to satisfy all their requests. Thus, we introduce a scheme that chooses which receivers should be discarded. Also, we study how the system is influenced by the Channel State Information and, in particular, how the knowledge of the eavesdropper's channel changes the achievable rates

Effectiveness of Hardiness Skill Training in Life Expectancy and Perceived Stress of Addicts in Addiction Treatment Centers across Alborz Province

The present research was conducted aiming at examining effectiveness of hardiness skill training in life expectancy and perceived stress of addicts in addiction treatment centers across Alborz province. The present research consists of all the addicts at addiction treatment centers across Alborz province. With regard to Morgan table, 210 individuals were selected as sample that 65 individuals have been found with highest stress level and lowest life expectancy after performing life expectancy and perceived stress questionnaire among which 40 individuals were selected via simple random method, and ultimately 20 individuals attended as experimental group and 20 individuals attended as control group. Statistical methods including mean, standard deviation, minimum and maximum variance of scores were used to display demographic characteristics of both groups. Covariance test has been used to compare status of groups with themselves before and after performing training classes and performing independent variables and comparing status of groups with each other before and after performing independent variable. Statistical analysis was made via software SPSS18. Experimental group received 3 months training during 10 sessions and control group received no training, that post-test was performed for both groups after ending the training program. The results obtained from covariance analysis indicated that hardiness training had a significant effect on life expectancy and perceived stress at p<0.01 in experimental group. It can be concluded that training hardiness affects improvement in perceived stress and increase in life expectancy

Compact Modeling of Intrinsic Capacitances in Double-Gate Tunnel-FETs

La miniaturització dels MOSFET en els circuits integrats ha elevat la tecnologia microelectrònica. Aquesta tendència també augmenta el grau de complexitat d'aquests circuits i els seus components bàsics. En els MOSFET convencionals, el corrent es basa en l'emissió termoiònica de portadors de càrrega, que per això limita el pendent subumbral en aquests transistors a 60 mV / dec. Per tant, per superar aquest límit i continuar amb la miniaturització per mantenir el ritme de la llei de Moore, es requereixen estructures alternatives. Entre aquestes, el transistor d'efecte de camp per túnel (TFET) es considera un possible successor de l'MOSFET. A causa del seu mecanisme alternatiu de transport de corrent, conegut com a túnel de banda a banda (B2B), el pendent subumbral en TFET pot fer-se inferior al límit de 60 mV / dec. Per comprendre i estimar el comportament dels TFET, no només com un element únic sinó també a nivell de circuit, es requereix un model compacte d'aquest dispositiu. En aquesta tesi es presenta un model basat en càrrega per descriure el comportament capacitiu d'un TFET de doble porta (DG TFET). No obstant això, la simplicitat i la flexibilitat de el model permeten usar-lo per a un altre tipus d'estructures TFET, com els TFET planars o de nanofils d'una sola porta (SG TFETs). El model és verificat amb les simulacions TCAD, així com amb mesures experimentals de TFET fabricats. El model de capacitància també inclou l'efecte dels elements paràsits. A més, en el context d'aquest treball també s'investiga la influència dels contactes de barrera Schottky en el comportament capacitiu dels TFET. Aquest model finalment es combina amb un model DC compacte existent per formar un model TFET compacte complet. A continuació, el model compacte s'implementa per a simulacions transitòries de circuits oscil·ladors d'anell basats en TFET.La miniaturización de los MOSFET en los circuitos integrados ha elevado la tecnología microelectrónica. Esta tendencia también aumenta el grado de complejidad de estos circuitos y sus componentes básicos. En los MOSFET convencionales, la corriente se basa en la emisión termoiónica de portadores de carga, que por ello limita la pendiente subumbral en estos transistores a 60 mV/dec. Por tanto, para superar este límite y continuar con la miniaturización para mantener el ritmo de la ley de Moore, se requieren estructuras alternativas. Entre estas, el transistor de efecto de campo por túnel (TFET) se considera un posible sucesor del MOSFET. Debido a su mecanismo alternativo de transporte de corriente, conocido como túnel de banda a banda (B2B), la pendiente subumbral en TFET puede hacerse inferior al límite de 60 mV/dec. Para comprender y estimar el comportamiento de los TFET, no sólo como un elemento único sino también a nivel de circuito, se requiere un modelo compacto de este dispositivo. En esta tesis se presenta un modelo basado en carga para describir el comportamiento capacitivo de un TFET de doble puerta (DG TFET). Sin embargo, la simplicidad y la flexibilidad del modelo permiten usarlo para otro tipo de estructuras TFET, como los TFET planares o de nanohílos de una sola puerta (SG TFETs). El modelo es verificado con las simulaciones TCAD, así como con medidas experimentales de TFET fabricados. El modelo de capacitancia también incluye el efecto de los elementos parásitos. Además, en el contexto de este trabajo también se investiga la influencia de los contactos de barrera Schottky en el comportamiento capacitivo de los TFET. Este modelo finalmente se combina con un modelo DC compacto existente para formar un modelo TFET compacto completo. A continuación, el modelo compacto se implementa para simulaciones transitorias de circuitos osciladores de anillo basados en TFET.Miniaturization of the MOSFETs on the integrated circuits has elevated the microelectronic technology. This trend also increases the degree of complexity of these circuits and their building blocks. In conventional MOSFETs the current is based on the thermionic—emission of charge carrier, which therefore limits the subthreshold swing in these transistors to 60 mV/dec. Hence, to overcome this limit and continue with down scaling to keep pace with the Moor’s law, alternative structures are required. Among these, the tunnel—field—effect transistor (TFET) is considered as a potential successor of the MOSFET. Due to its alternative current transport mechanism, known as band—to—band (B2B) tunneling, the subthreshold swing in TFETs can overcome the 60 mV/dec limit. In order to comprehend and estimate the behavior of TFETs, not only as a single element but also on the circuit level, a compact model of this device is required. In this dissertation a charge –based model to describes the capacitive behavior of a double—gate (DG) TFET is presented. However, simplicity and flexibility of the model allow to use it for other type of TFET structures such as single—gate (SG) planar or nanowire TFETs. The model is verified with the TCAD simulations as well as the measurement data of fabricated TFETs. The capacitance model also includes the effect of the parasitic elements. Furthermore, in the context of this work also the influence of Schottky barrier contacts on the capacitive behavior of TFETs is investigated. This model is finally combined with an existing compact DC model to form a complete compact TFET model. The compact model is then implemented for transient simulations of TFET—based inverter and ring—oscillator circuits

Characterization of triboelectric charging in data centers/display panel manufactures, and EMI visualization based on energy parcels method in high speed interconnections

This dissertation is composed of five papers. In the first three papers, triboelectric charging, which is the underlying cause of most electrostatic discharge (ESD), during daily human activities in data centers such as well-defined pattern walking, random walking, standing up from a chair, and taking off a sweater is investigated. Further, the effect of environmental condition (temperature and relative humidity), the footwear, and flooring material in building the static voltage and the discharge process are studied. In the fourth paper, triboelectric charge generation on the glass is investigated during the glass transportation by roller conveyor systems in display manufacturing. The underlying parameters that affect the static charging on both glass and rollers consisting of roller material, roller radius, transfer velocity, transfer acceleration, traveling distance, and relative humidity are explored. The fifth paper focuses on the shielding effectiveness (SE) of quad form-factor pluggable (QSFP) interconnections cages with heatsinks, which are often only optimized for thermal, mechanical, and volume manufacturing. Energy parcels and their trajectory concept are applied to electromagnetic waves (EM) to visualize the coupling paths in a QSFP cage with a rising heatsink. The rising heatsink creates a new coupling path for EM waves to leak to the cage and emit from the routers/switches chassis faceplate. An EMI mitigation technique is introduced and its performance is evaluated with SE measurement for the frequency of 1-40 GHz with and without the active operational of 40 Gbps optical module in a dual reverberation chamber --Abstract, page iv