Estimation of maximum oxygen uptake by evaluating cooper 12-min run test in female students of West Bengal, India

The main purpose of the study is to assess and compare the fitness in terms of maximum aerobic capacity (VO2 max) by cooper 12 min run among the urban female students and rural female students of West Bengal. Thirty young female students from each of the urban as well as rural sectors (age range, 16 – 21 years) of West Bengal were recruited by simple random sampling. Indirect estimation of VO2 max was done with help of 12 min running (Cooper test) of each group of subjects. This study also try to find whether there is any correlation and coefficient between VO2 max and age, weight, stature of the female students of urban sector and rural sector. The rural female young students do have a statistical significantly higher value of predicted maximum aerobic capacity (VO2 max) than the urban female young students with a probability of P

Emergence of the verification phase procedure for confirming 'true' VO2max

Traditional VO2max criteria are typically based on attainment of a VO2 plateau, and threshold values for the respiratory exchange ratio, heart rate and blood lactate concentration. Despite long-standing criticisms directed at these criteria, their use remains widespread. This article discusses an alternative procedure, termed the verification phase, for confirming the attainment of true VO2max. Following a continuous incremental exercise test to the limit of tolerance and appropriate recovery period, the verification phase is performed and is characterized by a supramaximal square wave exercise bout. Consistent peak VO2 values in the incremental and verification phases, confirms that a true VO2max has been attained. Six recent studies investigated the utility of the verification phase for evaluating true VO2max. These studies consistently found small insignificant mean differences between the maximal VO2 attained in the incremental and verification phases. However, this group mean approach does not identify individual subjects who may not have attained a true VO2max. Notably, only one of the six studies reported a criterion threshold to verify the VO2max of individual subjects. Further research is required to investigate the utility of different verification phase procedures and to establish a suitable verification criterion threshold for confirming true VO2max

Summary Report on the 2008 Image Acquisition Campaign for CwRS

The objective of the document is to summarise the results of the image acquisition campaign carried out by the JRC (IPSC, G03 (Agriculture Unit), CID Action) within the framework of the Control with Remote Sensing 2008.JRC.G.3 - Monitoring agricultural resource

HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes.

BACKGROUND: Nuclear reprogramming is potentially important as a route to cell replacement and drug discovery, but little is known about its mechanism. Nuclear transfer to eggs and oocytes attempts to identify the mechanism of this direct route towards reprogramming by natural components. Here we analyze how the reprogramming of nuclei transplanted to Xenopus oocytes exploits the incorporation of the histone variant H3.3. RESULTS: After nuclear transplantation, oocyte-derived H3.3 but not H3.2, is deposited on several regions of the genome including rDNA, major satellite repeats, and the regulatory regions of Oct4. This major H3.3 deposition occurs in absence of DNA replication, and is HIRA-and transcription-dependent. It is necessary for the shift from a somatic- to an oocyte-type of transcription after nuclear transfer. CONCLUSIONS: This study demonstrates that the incorporation of histone H3.3 is an early and necessary step in the direct reprogramming of somatic cell nuclei by oocyte. It suggests that the incorporation of histone H3.3 is necessary during global changes in transcription that accompany changes in cell fate.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

Interstitial Glucose and Physical Exercise in Type 1 Diabetes: Integrative Physiology, Technology, and the Gap In-Between

Continuous and flash glucose monitoring systems measure interstitial fluid glucose concentrations within a body compartment that is dramatically altered by posture and is responsive to the physiological and metabolic changes that enable exercise performance in individuals with type 1 diabetes. Body fluid redistribution within the interstitial compartment, alterations in interstitial fluid volume, changes in rate and direction of fluid flow between the vasculature, interstitium and lymphatics, as well as alterations in the rate of glucose production and uptake by exercising tissues, make for caution when interpreting device read-outs in a rapidly changing internal environment during acute exercise. We present an understanding of the physiological and metabolic changes taking place with acute exercise and detail the blood and interstitial glucose responses with different forms of exercise, namely sustained endurance, high-intensity, and strength exercises in individuals with type 1 diabetes. Further, we detail novel technical information on currently available patient devices. As more health services and insurance companies advocate their use, understanding continuous and flash glucose monitoring for its strengths and limitations may offer more confidence for patients aiming to manage glycemia around exercise

The point of maximum curvature as a marker for physiological time series

We present a geometric analysis of the model of Stirling. In particular we analyze the curvature of a heart rate time series in response to a step like increment in the exercise intensity. We present solutions for the point of maximum curvature which can be used as a marker of physiological interest. This marker defines the point after which the heart rate no longer continues to rapidly rise and instead follows either a steady state or slow rise. These methods are then applied to find analytic solutions for a mono exponential model which is commonly used in the literature to model the response to a moderate exercise intensity. Numerical solutions are then found for the full model and parameter values presented in Stirling

Occupational and leisure time physical activity in contrasting relation to ambulatory blood pressure

Background: While moderate and vigorous leisure time physical activities are well documented to decrease the risk for cardiovascular disease, several studies have demonstrated an increased risk for cardiovascular disease in workers with high occupational activity. Research on the underlying causes to the contrasting effects of occupational and leisure time physical activity on cardiovascular health is lacking. The aim of this study was to examine the relation of objective and self-report measures of occupational and leisure time physical activity with 24-h ambulatory systolic blood pressure (BP). Methods: Results for self-reported physical activity are based on observations in 182 workers (60% male, mean age 51 years), while valid objective physical activity data were available in 151 participants. The usual level of physical activity was assessed by 5 items from the Job Content Questionnaire (high physical effort, lifting heavy loads, rapid physical activity, awkward body positions and awkward positions of head or arms at work) and one item asking about the general level of physical activity during non-working time. On a regular working day, participants wore an ambulatory BP monitor and an accelerometer physical activity monitor during 24 h. Associations were examined by means of Analysis of Covariance. Results: Workers with an overall high level of self-reported occupational physical activity as well as those who reported to often lift heavy loads at work had a higher mean systolic BP at work, at home and during sleep. However, no associations were observed between objectively measured occupational physical activity and BP. In contrast, those with objectively measured high proportion of moderate and vigorous leisure time physical activity had a significantly lower mean systolic BP during daytime, while no differences were observed according to self-reported level of leisure time physical activity. Conclusions: These findings suggest that workers reporting static occupational physical activities, unlike general physically demanding tasks characterized by dynamic movements of large muscle groups, are related to a higher daily systolic BP, while high objective levels of moderate and vigorous leisure time physical activity are related to lower daytime systolic BP. Ambulatory systolic BP may be a physiological explanatory factor for the contrasting effects of occupational and leisure time physical activity

Marginalization of end-use technologies in energy innovation for climate protection

Mitigating climate change requires directed innovation efforts to develop and deploy energy technologies. Innovation activities are directed towards the outcome of climate protection by public institutions, policies and resources that in turn shape market behaviour. We analyse diverse indicators of activity throughout the innovation system to assess these efforts. We find efficient end-use technologies contribute large potential emission reductions and provide higher social returns on investment than energy-supply technologies. Yet public institutions, policies and financial resources pervasively privilege energy-supply technologies. Directed innovation efforts are strikingly misaligned with the needs of an emissions-constrained world. Significantly greater effort is needed to develop the full potential of efficient end-use technologies

A prospective, controlled clinical trial evaluating the clinical and radiological outcome after 3 years of immediately placed implants in sockets exhibiting periapical pathology

Abstract Objectives: The aim of the present study was to compare the clinical and radiological outcome of immediately placed implants in sockets with or without periapical pathology 3 years after implant placement. Materials and methods: Twenty-nine patients with immediate implant placement were clinically and radiologically followed 3 years after implant placement (test group: 16 patients without periapical pathology, control group: 13 patients with periapical pathologies). Clinical (full-mouth bleeding score, full-mouth plaque score, clinical attachment level measurements and width of keratinized mucosa buccaly of the implant) and radiological parameters (vertical distance from the implant shoulder to the first bone-to-implant contact [IS-BIC]) were assessed. Both 95% confidence intervals, as well as results of statistical tests (one-sample, two-sample and paired t-test) were provided. Results: The implant survival rate was 100% for all 29 implants after 3 years. The clinical and radiological parameters showed no statistically significant difference between the test and the control group at 3 years (two-sample t-test). The IS-BIC was between 1.54 +/- 0.88 mm (mesial, test) and 1.69 +/- 0.92 mm (distal, test). Between the 1- and 3-year visit the IS-BIC increased in both groups significantly on one side of the implant: 0.30 +/- 0.37 mm (mesial, test) and 0.33 +/- 0.43 mm (distal, control) (one-sample t-test). None of the 13 examined radiographs of implants immediately placed in sockets with periapical pathologies revealed retrograde peri-implantitis after 3 years. Conclusion: It is concluded within the limitations of this study, that after careful debridement of the extraction socket, immediate placement of implants into sites with periapical pathologies can be a successful treatment modality for at least 3 years with no disadvantages in clinical and radiological parameters to immediately placed implants into healthy sockets. To cite this article: Truninger TC, Philipp AOH, Siegenthaler DW, Roos M, Hämmerle CHF, Jung RE. A prospective, controlled clinical trial evaluating the clinical and radiological outcome after 3 years of immediately placed implants in sockets exhibiting periapical pathology. Clin. Oral Impl. Res. xx, 2010; 000-000