1,308 research outputs found
Dependence of Maximum Trappable Field on Superconducting Nb3Sn Cylinder Wall Thickness
Uniform dipole magnetic fields from 1.9 to 22.4 kOe were permanently trapped,
with high fidelity to the original field, transversely to the axes of hollow
Nb3Sn superconducting cylinders. These cylinders were constructed by helically
wrapping multiple layers of superconducting ribbon around a mandrel. This is
the highest field yet trapped, the first time trapping has been reported in
such helically wound taped cylinders, and the first time the maximum trappable
field has been experimentally determined as a function of cylinder wall
thickness.Comment: 8 pages, 4 figures, 1 table. PACS numbers: 74.60.Ge, 74.70.Ps,
41.10.Fs, 85.25.+
Alkaline earth catalysis for the 100% atom-efficient three component assembly of imidazolidin-2-ones
Evidence for Short Temporal Atmospheric Variations Observed by Infrasonic Signals: 1. The Troposphere
Infrasound monitoring is used in the forensic analysis of events, studying the physical processes of sources of interest, and probing the atmosphere. The dynamical nature of the atmosphere and the use of infrasound as a forensic tool lead to the following questions; (1) what is the timescale of atmospheric variability that affects infrasonic signals? (2) how do infrasound signals vary as a function of time? This study addresses these questions by monitoring a repetitive infrasound source and its corresponding tropospheric returns 54 km away. Source-receiver empirical Green\u27s functions are obtained every 20 s and used to demonstrate the effect of atmospheric temporal variability on infrasound propagation. In addition, observations are compared to predicted simulated signals based on realistic atmospheric conditions. Based on 127 events over 3 days, it is shown that infrasound properties change within tens of seconds. Particularly, phases can appear and disappear, the propagation time varies, and the signals\u27 energy fluctuates. Such variations are attributed to changes in temperatures and winds. Furthermore, atmospheric models can partly explain the observed changes. Therefore, this study highlights the potential of high temporal infrasound-based atmospheric sounding
Global periodicity conditions for maps and recurrences via Normal Forms
We face the problem of characterizing the periodic cases in parametric
families of (real or complex) rational diffeomorphisms having a fixed point.
Our approach relies on the Normal Form Theory, to obtain necessary conditions
for the existence of a formal linearization of the map, and on the introduction
of a suitable rational parametrization of the parameters of the family. Using
these tools we can find a finite set of values p for which the map can be
p-periodic, reducing the problem of finding the parameters for which the
periodic cases appear to simple computations. We apply our results to several
two and three dimensional classes of polynomial or rational maps. In particular
we find the global periodic cases for several Lyness type recurrences.Comment: 25 page
The emerging energy web
There is a general need of elaborating energy-effective solutions for managing our increasingly dense interconnected world. The problem should be tackled in multiple dimensions -technology, society, economics, law, regulations, and politics- at different temporal and spatial scales. Holistic approaches will enable technological solutions to be supported by socio-economic motivations, adequate incentive regulation to foster investment in green infrastructures coherently integrated with adequate energy provisioning schemes. In this article, an attempt is made to describe such multidisciplinary challenges with a coherent set of solutions to be identified to significantly impact the way our interconnected energy world is designed and operated. Graphical abstrac
Evaluation of Novel Imidazotetrazine Analogues Designed to Overcome Temozolomide Resistance and Glioblastoma Regrowth
The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multi- forme (GBM) cell lines and primary culture models are reported. Dose–response analysis of cultured GBM cells revealed that DP68 is more potent than DP86 and TMZ and that DP68 was effective even in cell lines resistant to TMZ. On the basis of a serial neurosphere assay, DP68 inhibits repop- ulation of these cultures at low concentrations. The efficacy of these compounds was independent of MGMT and MMR func- tions. DP68-induced interstrand DNA cross-links were dem- onstrated with H2O2-treated cells. Furthermore, DP68 induced a distinct cell–cycle arrest with accumulation of cells in S phase that is not observed for TMZ. Consistent with this biologic response, DP68 induces a strong DNA damage response, including phosphorylation of ATM, Chk1 and Chk2 kinases, KAP1, and histone variant H2AX. Suppression of FANCD2 expression or ATR expression/kinase activity enhanced anti- glioblastoma effects of DP68. Initial pharmacokinetic analysis revealed rapid elimination of these drugs from serum. Collec- tively, these data demonstrate that DP68 is a novel and potent antiglioblastoma compound that circumvents TMZ resistance, likely as a result of its independence from MGMT and mismatch repair and its capacity to cross-link strands of DN
Two Bessel Bridges Conditioned Never to Collide, Double Dirichlet Series, and Jacobi Theta Function
It is known that the moments of the maximum value of a one-dimensional
conditional Brownian motion, the three-dimensional Bessel bridge with duration
1 started from the origin, are expressed using the Riemann zeta function. We
consider a system of two Bessel bridges, in which noncolliding condition is
imposed. We show that the moments of the maximum value is then expressed using
the double Dirichlet series, or using the integrals of products of the Jacobi
theta functions and its derivatives. Since the present system will be provided
as a diffusion scaling limit of a version of vicious walker model, the ensemble
of 2-watermelons with a wall, the dominant terms in long-time asymptotics of
moments of height of 2-watermelons are completely determined. For the height of
2-watermelons with a wall, the average value was recently studied by Fulmek by
a method of enumerative combinatorics.Comment: v2: LaTeX, 19 pages, 2 figures, minor corrections made for
publication in J. Stat. Phy
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