Crónica de una "una larga jornada laboral"

Intervención en la Mesa Redonda de la "Jornada sobre la historia y vida cotidian de la Facultad de Derecho", celebrada en el Salón de Actos, el día 12 de mayo de 2005, en conmemoración del XXV Aniversario de la creación del Centro

El Trastorno por Déficit de Atención e Hiperactividad en Educación Infantil. Intervención para la mejora de las habilidades atencionales

El en presente trabajo se presenta una revisión teórica acerca del Trastorno por Déficit de Atención e Hiperactividad. Este trastorno está cada vez más presente en las aulas, por lo que es necesaria la formación de los docentes respecto al mismo para poder ofrecer a este tipo de alumnado una respuesta educativa adecuada. A pesar de los escasos diagnósticos realizados en Educación Infantil es imprescindible una detección temprana del problema, para poder subsanar las dificultades, tanto académicas como personales y sociales, que ocasiona. Se presenta además un programa de prevención centrado en el déficit de atención, que pretende conseguir mejoras en las habilidades atencionales del alumnado de Educación Infantil.Grado en Educación Infanti

The rights of child in the discourse of childhood early education and care policy

An increasing number of investigations are highlighting the vital importance of the early years of life for subsequent educational development and social integration, as well as in relation to the recognition of the rights of children and the economic performance for the individual and for society to invest in these years. There is no doubt that are aspects many that need to be addressed concerning this issue, but what is presented here lies in the proposal to open up new questions in the comprehensive policy aimed at early childhood education with a view to contribute to the fulfillment of children's rights; most especially the right to early childhood education and care, which are provided for in existing national and international regulationsInvestigaciones cada vez más numerosas al respecto están poniendo de manifiesto la importancia vital de los primeros años de vida para el desarrollo educativo posterior y la integración social, así como en relación con el reconocimiento de los derechos de los niños y el rendimiento económico que supone para el individuo y para la sociedad invertir en estos años. Sin duda son muchos los aspectos que han de ser abordados, pero lo que aquí se presenta radica en la propuesta de abrir nuevos interrogantes en la política integral dirigida a la primera infancia con una mirada educativa, para contribuir en el cumplimiento de los derechos del niño, muy especialmente el derecho a la educación y atención de la primera, estipulados en las normativas nacionales e internacionales vigente

Compulsory Preschool in Latin America: Comparative Evolution and Future Challenges

The establishment of Early Childhood Education (ECE) as a key to the success of different aims on the global agendas—Education for All Framework (EFA), Sustainable Development Goals (SDGs), among others—has contributed to the extension of ECE programs and preschool around the world. Latin American countries have also advocated for the development agendas, with the essential role played by education for sustainable human development. Over the last decades, these countries have made dramatic efforts to increase preschool coverage, with a broad success that favors the level of attainment in primary education. Even when this expansion has been broadly recognized as a significant progress for the improvement of ECE access for many young children in the region, it has been acknowledged that the extent of this expansion has been very unequal. The comparative study helps to reveal the different developments, as well as the diverse situations and political agendas for ECE, when Latin American countries adopt international agendas to their particular realities and education contexts. In this view, this study aims to identify the broad trends trying to include the affluent frames and evolutions of compulsory preschool in Latin America in order to open a space for debate around the particular pathways that this ECE policy has implicated in this region

Effects of Kv1.3 inhibition in type 2 diabetes-induced cardiac electrical remodeling.

217 p.Background: Diabetic patients have prolonged cardiac repolarization and a higher risk ofarrhythmia. Besides, diabetes activatesthe innate immune system, resulting in higher levels of plasmatic proinflammatory cytokinessuch as TNFa and IL1b, which are described to prolong ventricular repolarization.Methods: Most of the current knowledge on diabetic cardiac electrical remodeling derivesfrom type 1 diabetic animals. Here, we characterize a metabolic model of type 2 diabetes withprolonged cardiac repolarization. Sprague-Dawley rats were fed on high fat diet (45% Kcalfrom fat) for 6 weeks, and a low dose of streptozotozin was intraperitoneally injected at week2. Body weight and fasting blood glucose were measured and electrocardiograms to consciousanimals were recorded weekly. Plasmatic lipid profile, insulin, cytokines and arrhythmiasusceptibility were determined at the end of the experimental period. The transient outwardK+ current and action potentials were recorded in isolated ventricular myocytes by patchclamp.Animals were also treated with PAP-1, an inhibitor of Kv1.3 channel that has animmunomodulatory role. Results: Type 2 diabetic animals showed insulin resistance,hyperglycemia and higher levels of plasma cholesterol, triglycerides, TNFa and IL1b thancontrols. They also developed bradycardia and prolonged QTc-interval duration that resultedin increased susceptibility to severe ventricular tachycardia under cardiac challenge. Actionpotential duration (APD) was prolonged in control cardiomyocytes incubated 24h with plasmaisolated from diabetic rats. However, adding TNFa and IL1b receptor blockers to the serum ofdiabetic animals prevented the increased APD. Inhibition of Kv1.3 reduced the circulaitingcytokines including TNFa and IL1B. It had an antidiabetic effect improving insulin resistanceand controlling the glucose while reduced the prolongation of QTc and the susceptibility toarrhythmia in the diabetic rats.Conclusions: The elevation of the circulating levels of TNFa and IL1b are responsible forimpaired ventricular repolarization and higher susceptibility to cardiac arrhythmia in ourmetabolic model of type 2 diabetes. Thus, immunomodulation by inhibition of Kv1.3 hasantidiabetic effects while improving the electrical alterations of the diabetic heart. Theseresults make the immune system a potential target for the treatment of diabetes and itsassociated alterations

Seasonal Variation of Essential Oil Yield and Composition of Sage (Salvia officinalis L.) Grown in Castilla - La Mancha (Central Spain)

Links between phenology, yield and composition of the essential oil of common sage, Salvia officinalis L., grown in Guadalajara (Central Spain) were determined in the different phases of the biological cycle during one year. Data showed an average yield about 1.0%. The analysis of the oil components was carried out by GC-FID and GC/MS. The main oil constituent was alpha thujone (40.1 - 46.5%). Other identified compounds are beta pinene (2.6 - 4.5%), cineole (3.5 - 8.7%), beta thujone (4.1 - 5.6%), camphor (4.1 - 8.0%), borneol (1.3 - 3.7%), alpha humulene (3.8 - 7.3%), viridiflorol (3.4-12.6%) and manool (0.1-4.5%). The highest yield of oil was obtained in the period of full flowering and the highest concentration of alpha thujone in the period of initial flowering

Papel de la osmolaridad en el desarrollo de patología inflamatoria de la superficie ocular

Revisión sobre el papel que juega la osmolaridad en las patologías inflamatorias de la superficie ocular centrándonos principalmente en el ojo seco. Abarca desde el 1980 hasta la actualidad. Se describen las diferentes capas de la superficie ocular y los componentes de la unidad funcional lagrimal, así como el ojo seco y su clasificación actual. Se centra en los estudios que hay sobre el papel de la osmolaridad en la patología del ojo seco y en llegar a una conclusión sobre si juega un papel relevante o no en esta patología y en caso de hacerlo si es como causa o como efecto de ella. Dada la controversia que hay en la comunidad científica sobre este tema se pretende dar una visión general y llegar a una conclusión a partir de ella.Grado en Óptica y Optometrí