1,792 research outputs found
Coopelesca en línea móvil
Proyecto de graduación (Bachillerato en Ingeniería en Computación) Instituto Tecnológico de Costa Rica, Escuela de Ingeniería en Computación, 2013Para la etapa final del proyecto se ha logrado desarrollar la aplicación móvil
según las especificaciones planteadas al inicio, y en el transcurso del proyecto se ha
ido teniendo que implementar algunas funcionalidades necesarias para el correcto
funcionamiento de la aplicación y cambiando algunos detalles de diseño.
A continuación se presentan los alcances de la práctica de especialidad:
a) Las funcionalidades básicas descritas en los primeros informes.
a.1 Recibir, muestra, borrar y calificar notificaciones para usuario con cuenta y el
recibir y mostrar notificaciones para usuarios generales.
a.2 Validación de usuario, para usuarios con una cuenta.
a.3 Solicitud de cuenta para usuarios que todavía no poseen cuenta.
a.4 Muestra de la siguiente información sobre los servicios suscritos a una
cuenta: Información general del servicio, historial de consumo de energía,
historial de facturación y calendario de facturación y lectura.
a.5 Creación de reportes según sus necesidades, tales como: Reporte de falla
eléctrica, reporte fotográfico de una situación relevante, consulta de
disponibilidad de los servicios de internet y cable, solicitud para ser contactando
por la Cooperativa y reporte de queja.
b) A la aplicación se le implemento un sistema de seguridad con una funcionalidad
autorizadora llama OAuth2 (DotNetOpenAuth), para el consumo de los servicios
webs, donde la aplicación solicita un “token” el cual luego utilizara en todas las
llamadas a los servicios web.
c) Implementación de manejo de base de datos local, ya que para ciertas
secciones de la aplicación, la información que se maneja es mucha como para
estarla invocando por medio de los servicios web constantemente.
Este proyecto tiene como objetivo principal estrechar los lazos con el asociado,
introduciéndose en el muy creciente y demandado mercado de los dispositivos móviles
(con Android).COOPELESCA
Instituto Tecnológico de Costa Rica Sede San Carlos. Escuela de Ingeniería en Computación
Análisis de la fertilidad de los suelos de Alto Loica en San Pedro de Melipilla, Región Metropolitana (Chile)
In Chile, soil erosion is one of the main environmental problems as over 40% of the country’s soils are subjected to erosion, limiting its capacity to generate goods and services. In the central areas of the country, this phenomenon is intensified at the coastal mountain ridge, with rural areas as the most affected. This is the case of the commune of San Pedro de Melipilla, located at the SW of the Metropolitan Region. The aim of this study is to analyze the physical and chemical characteristics of the soil in Alto Loica, which is a rural area located in the southern area of the commune of San Pedro. The study was carried out in four hydrographic micro-basins through the sampling of soils and the analysis of soil pits in Alto Loica. The results show critical deficits in the concentrations of micro and macro nutrients, resulting in low fertility and quality of soils. Thus, the soils of Alto Loica are not apt for agriculture-livestock use, limiting its use to forestry. Moreover, these could be related to poor agricultural practices in the past, which led to soil erosion in the area. Overall, this study could become a conceptual and referential framework for future soil restauration and rehabilitation studies aiming at recovering the soil ability to generate goods and services.En Chile, la erosión es el principal problema ambiental debido a que sobre el 40% de los suelos en el país está con problemas de erosión, limitando la capacidad de éstos para generar bienes y servicios. En la zona central del país, este fenómeno se intensifica en la Cordillera de la Costa, siendo las comunas rurales las más afectadas, principalmente la comuna de San Pedro de Melipilla, al SW de la Región Metropolitana. Este estudio tiene como objetivo analizar las propiedades físicas y químicas del suelo de Alto Loica, sector rural localizado al sur de la comuna de San Pedro. El estudio se efectuó en 4 microcuencas hidrográficas en Alto Loica, mediante el muestreo de suelos y el análisis de calicatas. Los resultados reflejaron que existen déficit críticos en las concentraciones de micro y macronutrientes, debido a lo cual los suelos presentan baja fertilidad y baja calidad y no son aptos para el desarrollo agropecuario, limitándose su uso solo a aptitud forestal. Por otra parte, esto se puede asociar a malas prácticas agrícolas efectuadas en el pasado, que derivaron en la erosión de los suelos del sector. Este estudio puede contribuir como un marco conceptual y referencial para futuros estudios de restauración y rehabilitación de suelos con el fin de recuperar la propiedad de los suelos de generar bienes y servicios
A multimarket approach to estimate a New Keynesian Phillips Curve
We propose a new approach to estimate and "hybrid" New Keynesian Phillips Curve (NKPC) that includes demand pressures coming from disequilibrium relations in three different markets: (1) the monetary and financial, (2) the international, and (3) the labor market. In the application, our results show that all three markets contribute to the evolution of inflation. However, the effect of shocks on equilibrium in the labour market and short run movements in cyclical output are relatively more important than other shocks. Based on econometric tests, this specification is proved to be superior to the traditional NKPC that includes a single variable to account for demand pressures.
Influencia burocrática en la formulación de política pública: el caso del sistema de alta dirección pública en Chile
How bureaucrats influence in policy formulation? The mainstream of literature postulates that the policy formulation is led by politicians who define the scope of these. However, alternative approaches argue that bureaucrats influence
in this process. The aim of this study is to analyze the mechanisms whereby bureaucrats influence policy formulation, through the case study of Sistema de Alta Dirección Pública en Chile (SADP). Evidence indicates that bureaucrats influence on those policies that politicians are not interested, leaving wide
areas of discretion, and for a specific expertise that differentiates them from other actors as technocrats or technopols.¿Cómo influencian los burócratas en la formulación de política pública? Parte importante de la literatura ha postulado que la formulación de política es dirigida por los políticos, quienes definen los alcances de éstas. No obstante enfoques alternativos plantean que los burócratas ejercen influencia en este proceso. El objetivo del presente trabajo es, a través del estudio de caso del Sistema de Alta Dirección Pública en Chile (SADP), analizar los mecanismos a través de los cuales los burócratas influyen la formulación de política. La evidencia indica que los burócratas influenciarían cuando los políticos no están interesados en la política pública, dejando amplios espacios de discrecionalidad,
y por un tipo de experticia particular que los diferenciaría de otros actores como tecnócratas o tecnopolítico
CO-DESARROLLO DE VARIEDADES ENTRE AGRICULTORES, CIENTÍFICOS Y PROFESIONALES, BIODIVERSIDAD Y OTRAS COSAS
N° ISBN - 978-2-7380-1284-5International audienceThis paper assesses a long-term, on-going experience on participatory plant breeding (PPB) in food crops. It involves researchers, extension agents, and producers' organizations whose members live in marginal and poor areas in five Central American countries. This experience confirms the feasibility, despite adverse conditions, for implementing novel institutional arrangements, renewed research approaches and practices leading to the emergence of sustainable innovations processes and systems which reconcile production and conservation. By combining scientific and farmer knowledge, the project stakeholders were able to jointly develop a large array of varieties suited to a diversity of unfavourable local environmental and socioeconomic contexts, an array much larger indeed than what was available locally before. Over time, the project evolved beyond collaboration and entered into a true partnership, by developing governance mechanisms which allow a greater protagonism from farmers' organizations. Nevertheless, this experience also illustrates limitations and challenges of such approaches, especially when social demand for extending and scaling up increase, nurtured by the early successes and know-how achieved during the initial phases of the project. To respond to this challenge, major bottlenecks need to be addressed, such as ensuring the hiring of a young generation of PPB scientists to continue the work of their elders, and the necessary funding for these activities. This would however imply that adequate policy support indeed exists for science to effectively contribute to poverty mitigation
Nuevos registros de moluscos terrestres (Gastropoda: Stylommatophora) de Antofagasta, norte de Chile
Se presentan nuevos registros para Bostryx holostoma (Pfeiffer, 1846), Pupoides minimus (Philippi, 1860), Stephacharopa calderaensis Miquel y Araya, 2013 y una especie no identificada de la familia Charopidae, basados en ejemplares recolectados cerca de la ciudad de Antofagasta, en el norte de Chile. Se presenta el primer registro de S. calderaensis desde su descripción, extendiendo su distribución conocida hacia el norte en cerca de 350 km. Se presentan además detalles de la protoconcha de B. holostoma que también extiende su intervalo de distribución 145 km al sur. El microhábitat de estas especies en litorrefugios podría explicar la presencia de estos pequeños moluscos terrestres en el hiperárido norte chileno, destacando asimismo la necesidad de estudios adicionales en esta fauna poca conocida.New records for Bostryx holostoma (Pfeiffer, 1846), Pupoides minimus (Philippi, 1860), Stephacharopa calderaensis Miquel & Araya, 2013 and an unidentified charopid species are presented on the basis of specimens collected near the city of Antofagasta, in northern Chile. This is the first record for S. calderaensis after its description, extending its known distribution about 350 km northwards. Details on the protoconch of B. holostoma are presented for the first time, and this species extends its distributional range 145 km southwards. The microhabitat of these species in litho-refugia may explain the presence of these minute terrestrial mollusks in hyper arid northern Chile, further highlighting the need of additional studies of this neglected fauna.Fil: Araya, Juan Francisco. Universidad de Atacama; Chile. Universidad de Concepción; ChileFil: Miquel, Sergio Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales ; ArgentinaFil: Martínez, Edmundo. Antofagasta Minerals; Chil
Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake
Indexación: Web of Science.Poly(amidoamine) dendrimers are the most recognized class of dendrimer. Amino-terminated (PAMAM-NH2) and hydroxyl-terminated (PAMAM-OH) dendrimers of generation 4 are widely used, since they are commercially available. Both have different properties, mainly based on their different overall charges at physiological pH. Currently, an important function of dendrimers as carriers of short single-stranded DNA has been applied. These molecules, known as antisense oligonucleotides (asODNs), are able to inhibit the expression of a target mRNA. Whereas PAMAM-NH2 dendrimers have shown to be able to transfect plasmid DNA, PAMAM-OH dendrimers have not shown the same successful results. However, little is known about their interaction with shorter and more flexible molecules such as asODNs. Due to several initiatives, the use of these neutral dendrimers as a scaffold to introduce other functional groups has been proposed. Because of its low cytotoxicity, it is relevant to understand the molecular phenomena involving these types of dendrimers. In this work, we studied the behavior of an antisense oligonucleotide in presence of both types of dendrimers using molecular dynamics simulations, in order to elucidate if they are able to form stable complexes. In this manner, we demonstrated at atomic level that PAMAM-NH2, unlike PAMAM-OH, could form a well-compacted complex with asODN, albeit PAMAM-OH can also establish stable interactions with the oligonucleotide. The biological activity of asODN in complex with PAMAM-NH2 dendrimer was also shown. Finally, we revealed that in contact with PAMAM-OH, asODN remains outside the cells as TIRF microscopy results showed, due to its poor interaction with this dendrimer and cell membranes.http://nanoscalereslett.springeropen.com/articles/10.1186/s11671-016-1260-
Incidence and prevalence of salivary gland tumours in Valparaiso, Chile
Background
: To determine the incidence and prevalence of salivary gland tumours in the province of Valparaíso,
Chile.
Material and Methods
: Retrospective review of salivary gland tumours diagnosed between the years 2000 and
2011 from four local pathology services. Information on demographics and histopathology were retrieved from
the medical records.
Results
: The study sample consisted of 279 salivary gland tumours. Prevalence and incidence rates per 100.000
persons were 15.4 and 2.51, respectively. Most of the neoplasms corresponded to benign tumours (70.3%). The
most affected gland was the parotid gland. Pleomorphic adenoma was the most common benign tumour (53.8%)
and mucoepidermoid carcinoma was the most common malignant tumour (7.2%).
Conclusions
: Salivary gland tumours are uncommon neoplasms that usually arise in the parotid gland. Pleomor-
: Salivary gland tumours are uncommon neoplasms that usually arise in the parotid gland. Pleomorphic adenoma and mucoepidermoid carcinoma were the most common benign and malignant tumours reported
in this series
Scientists and public policy : the incidence of a network in the treatment of a law on land management
Nuestro trabajo tiene como objetivo aplicar conceptos de la teoría de los sistemas complejos y herramientas
del análisis de redes sociales para describir y analizar el surgimiento y la evolución de una red social
conformada por científicos, docentes, graduados y funcionarios públicos de diferentes organismos
científicos y académicos, que crearon y participaron de un equipo multidisciplinario que elaboró un informe
sobre un proyecto de ley de Ordenamiento Territorial y Usos del Suelo de la provincia de Mendoza en el año
2006.
Para la compresión de la evolución del proceso de elaboración del proyecto de ley de ordenamiento
territorial y de usos del suelo, organizaremos la estructura del trabajo de la siguiente manera:
- Primero aplicaremos aspectos teóricos y metodológicos, basados en la sistematización realizada por
Rolando García en su libro “Sistemas Complejos. Conceptos, método y fundamentación epistemológica de
la investigación interdisciplinaria", para realizar el recorte del sistema objeto de estudio.
- En segundo lugar utilizaremos la Teoría de Análisis de Redes Sociales para describir la composición y
estructura del sistema (nodos y vínculos) en cada momento. La estructura del sistema en cada momento
significativo será graficada por medio el Software Ucinet 6 y NetDraw.
- Por último, haremos referencia a las dificultades que tuvo el proceso desde el punto de vista de las
condicionalidades que generaban los modelos mentales que portaban los participantes.Our work aims to apply concepts of the theory of complex systems and tools of social network analysis to
describe and analyze the emergence and development of a social network made up of scientists, teachers,
graduates and civil servants from different agencies and academic scientists , who created and participated
in a multidisciplinary team that prepared a report on a bill of Land Management and Land use in the province
of Mendoza in 2006.
For understanding the evolution of the process of drafting the bill on land management and land use,
organize the structure of work as follows:
- First apply theoretical and methodological aspects, based on the systematization by Rolando Garcia in his
book "Complex Systems. Concepts, methods and epistemological foundation of interdisciplinary research, to
make the cut in the system under study.
- Secondly we use the theory of social network analysis to describe the composition and structure of the
system (nodes and links) in each time. The structure of the system at any time will be significant graphics
software Ucinet half NetDraw and 6.
- Finally, we will make reference to the difficulties was the process from the standpoint of the conditions that
generated mental models carrying participants.Fil: Burlot, Juan Gastón.
Universidad Nacional de Cuyo. Facultad de Ciencias Políticas y SocialesFil: Medalla Araya, Adolfo R..
Universidad Nacional de Cuyo. Facultad de Ciencias Políticas y Sociale
Isolation of modulators of Organic Anion Transporting Polypeptides (OATPs) from Rollinia emarginata Schlecht (Annonaceae)
Comparative Medicine - OneHealth and Comparative Medicine Poster SessionOrganic Anion Transporting Polypeptides (OATPs) comprise a superfamily of sodium-independent membrane transporters which are involved in transporting numerous endogenous and exogenous substances. OATPs are expressed in different tissues such as intestine, liver, kidney and brain, and are responsible for the uptake of important drugs including cholesterol-lowering agents (statins), endothelin receptor antagonists (sartans), the anticancer drugs methotrexate, SN-38, paclitaxel and docetaxel, as well as the antibiotic rifampicin. Through a strategic collaboration, we search for novel small molecules from the organic extract of Rollinia emarginata Schlecht. (Annonaceae) that interact with the liver specific OATP1B1 and OATP1B3 applying a bioassay guided isolation approach. The organic extract was fractionated using different chromatographic techniques, and each fraction was tested for its effect on OATP1B1- and OATP1B3-mediated transport of 1µM estrone-3-sulfate and 0.1µM estradiol-17||-glucuronide. Several inhibitors, including both substrate-specific and non-specific, were isolated and chemically identified. For instance, the compound Quercetin 3-O-||-L-arabinopyranosyl (1 ->2)||-L-rhamnopyranoside was shown to inhibit both OATP1B1- and OATP1B3-mediated transport of estradiol-17||-glucuronide by more than 90%, relative to control (DMSO). However, with respect to transport of 1µM estrone-3-sulfate it inhibits OATP1B1 by only 45% while, interestingly, stimulating transport mediated by OATP1B3 (2 fold over control). Thanks to our collaborative efforts, we were able to show that plants can be suitable source of small molecules that modulate OATPs using bioassay guided isolation approach
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