À la croisée des chemins. Musiques savantes-musiques populaires. Hommage à George Sand. Saint-Jouin-de-Milly, 1999 (« Modal Poche »).

Il s'agit de la publication des actes d'un colloque qui a eu lieu à La Châtre en octobre 1997. Le propos est de penser les interactions du musical populaire et du musical savant à partir de la production littéraire de George Sand autour de la musique. L'ouverture de Michel de Lannoy, « George Sand, la musique et l'indicible », souligne avec force que George Sand fut l'une des premières à incarner qu'on ne peut avoir un discours sur la musique savante sans faire référence aux musiques p..

Imaginaires auvergnats. Cent ans d'intérêt pour les musiques traditionnelles populaires (l'exemple du Centre France). Saint-Jouin-de-Milly, AMTA et FAMDT, 1999 (« Modal Poche »).

Cet ouvrage est la publication des actes de rencontres qui se sont tenues à Riom en novembre 1996, organisées par la Fédération des associations de musiques et danses traditionnelles (FAMDT) et l'Agence des musiques traditionnelles en Auvergne (AMTA), sous la coordination de José Dubreuil. L'objectif est de faire émerger toute la complexité des musiques populaires et de montrer quelles représentations elles ont engendrées au cours de ce siècle. Le livre comporte quatre chapitres. Le pr..

Plantar pressure analysis : identifying risk of foot and ankle injury in soccer players

The aim of this study was to determine whether risk factors for foot or ankle injuries could be identified using quantitative foot measurements. Male and female soccer players of all levels from 9 to 40 years old were included in this cross-sectional study. Soccer history, foot and ankle function and injury history were investigated. Foot symmetry, length and arch height flexibility and plantar pressure captured with a mat were measured. All variables showing a significant correlation (P ≤ .05) and the presence of at least one foot or ankle injury were integrated into a multivariate logistic regression model using forward stepwise selection. We recruited 277 players (196 males), and 79 participants had sustained at least one foot or ankle soccer-related injury. The significant variables were as follows: age, gender, pressure on the lateral heel and on the fourth and fifth metatarsals. Based on the model, the area under the ROC curve was 81.2%. To achieve a specificity of 80%, the corresponding sensitivity was 72.2%. Plantar pressure measurements can objectively assess foot alignment. Increased pressure on the lateral heel and fourth and fifth metatarsal cavovarus foot type represent a risk factor for foot and ankle injuries in soccer. Level of evidence: IV

“Blurred boundaries”: When nurses and midwives give anti-vaccination advice on Facebook

© The Author(s) 2022. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1177/09697330211041749Background: Nurses and midwives have a professional obligation to promote health and prevent disease, and therefore they have an essential role to play in vaccination. Despite this, some nurses and midwives have been found to take an anti-vaccination stance and promulgate misinformation about vaccines, often using Facebook as a platform to do so. Research question: This article reports on one component and dataset from a larger study – ‘the positives, perils and pitfalls of Facebook for nurses’. It explores the specific issue of nurses and midwives who take an anti-vaccination stance, deemed to be unprofessional by crossing professional boundaries and by providing medical information on Facebook that is not within their scope of practice. Participants: Data were collected via an online worldwide survey from nurse and midwife participants, distributed and ‘snowballed’ through relevant nursing and midwifery groups on Facebook. In total, 1644 Registered Nurses and Midwives, and Enrolled Nurses worldwide attempted the online survey. There were 1100 (66.9%) completed surveys and 54 partially (33.1%) completed surveys. Semi-structured interviews were also conducted online using Skype® with 17 participants in Australia. Ethical considerations: Ethical processes and procedures have been adhered to relating to privacy, confidentiality and anonymity of the participants. Findings/results: A mixed-methods approach was used, including descriptive and content analysis of the quantitative survey data and thematic analysis of the qualitative interview data. The main theme ‘blurred boundaries’ was generated, which comprised three sub-themes: ‘follow the science, ‘abuse of power and erosion of trust’ and ‘the moral and ethical responsibility to safeguard public health’. The results offer an important and unique understanding of how nurses and midwives interpret the conduct of fellow health professionals as unprofessional and crossing the professional boundary if they used Facebook to promulgate anti-vaccination messages and/or give medical advice online. Conclusion: There are many positives and negatives for nurses and midwives associated with using Facebook for personal and professional communication, which is in keeping with the results of the larger study from which this article is taken. Professional behaviour is a key theme in the larger research as is the ethical construct of ‘every act has a consequence’; however, in this article, the theme ‘blurred boundaries’ offers an overall understanding of how nurses and midwives interpret the behaviour of their colleagues who espouse anti-vaccination sentiment and/or give medical advice online that is outside their scope of practice and education.Peer reviewe

An oligofluorene truxene based distributed feedback laser for biosensing applications

The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported. The protein avidin was detected down to View the MathML source1μgmL−1 using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturbed by Bovine Serum Albumin up to View the MathML source50,000μgmL−1. Our biosensor offers a new detection platform that is both highly sensitive, modular and potentially re-usable

Male frequent attenders of general practice and their help seeking preferences

Background: Low rates of health service usage by men are commonly linked to masculine values and traditional male gender roles. However, not all men conform to these stereotypical notions of masculinity, with some men choosing to attend health services on a frequent basis, for a variety of different reasons. This study draws upon the accounts of male frequent attenders of the General Practitioner's (GP) surgery, examining their help-seeking preferences and their reasons for choosing services within general practice over other sources of support. Methods: The study extends thematic analysis of interview data from the Self Care in Primary Care study (SCinPC), a large scale multi-method evaluation study of a self care programme delivered to frequent attenders of general practice. Data were collected from 34 semi-structured interviews conducted with men prior to their exposure to the intervention. Results: The ages of interviewed men ranged from 16 to 72 years, and 91% of the sample (n= 31) stated that they had a current health condition. The thematic analysis exposed diverse perspectives within male help-seeking preferences and the decision-making behind men's choice of services. The study also draws attention to the large variation in men's knowledge of available health services, particularly alternatives to general practice. Furthermore, the data revealed some men's lack of confidence in existing alternatives to general practice. Conclusions: The study highlights the complex nature of male help-seeking preferences, and provides evidence that there should be no 'one size fits all' approach to male service provision. It also provides impetus for conducting further studies into this under researched area of interest. © 2011 WPMH GmbH

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

Numerous genetic and epigenetic alterations render cancer cells selectively dependent on specific genes and regulatory pathways, and represent potential vulnerabilities that can be therapeutically exploited. Here we describe an RNA interference (RNAi)-based synthetic interaction screen to identify genes preferentially required for proliferation of p53-deficient (p53-) human cancer cells. We find that compared to p53-competent (p53+) human cancer cell lines, diverse p53- human cancer cell lines are preferentially sensitive to loss of the transcription factor ETV1 and the DNA damage kinase ATR. In p53- cells, RNAi-mediated knockdown of ETV1 or ATR results in decreased expression of the telomerase catalytic subunit TERT leading to growth arrest, which can be reversed by ectopic TERT expression. Chromatin immunoprecipitation analysis reveals that ETV1 binds to a region downstream of the TERT transcriptional start-site in p53- but not p53+ cells. We find that the role of ATR is to phosphorylate and thereby stabilize ETV1. Our collective results identify a regulatory pathway involving ETV1, ATR, and TERT that is preferentially important for proliferation of diverse p53- cancer cells

International policy responses and early management of threats posed by the SARS-CoV-2 pandemic to social care

Context: People with prior health conditions are susceptible to severe and sometimes fatal outcomes of the novel coronavirus SARS-CoV-2, that causes the disease COVID-19. The protection of the capacity of systems for social care was thus an important consideration for governments in the early stages of the global pandemic. Objectives: This paper reports and discusses the results of a rapid review of international early policy responses for the protection of social care systems after the World Health Organization (WHO) announced that SARS-CoV-2 had evolved into a pandemic. Literature was collected in March 2020. Method: Rapid online review of government responses to the SARS-CoV-2 pandemic using official government statements and press reports from 13 countries. Findings: The analysis of early responses in and about social care to the pandemic suggested an initial focus on avoiding the outbreak of the virus in care homes, with first steps being to limit visitors in these contexts and considering ways to isolate residents with symptoms or a confirmed infection. Responses to protect people receiving social care in their homes and schemes to support informal or family carers were less prominent. Limitations: Only publications in the public domain and in local languages of the 13 countries were considered for this analysis. It is possible that further strategies and responses were not made available to the public and are therefore not included, which limits this article’s scope for analysis. Implications: The findings of this article can support reflection on the trajectory of policy responses to the threats that SARS-CoV-2 poses to social care. They can thereby potentially inform planning and policy responses for enhanced pandemic preparedness and stronger social care systems in the future

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