Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads

Methods are provided for selecting a bacterium capable of reducing pathogenic bacterial colonization of the intestinal tract in a subject comprising selecting the bacterium capable of migrating at least 0.75 cm from the point of inoculation on motility agar after incubation for 24 hours at 37° C. It is also capable of migrating from the point of inoculation to a diameter of at least 1.5 cm based on the farthest colonies from the point of inoculation on motility agar after incubation for 24 hours at 37° C. Bacteria selected using the method and compositions comprising these bacteria are also provided

Armed to Farm: Developing Training Programs For Military Veterans in Agriculture

Farming offers a viable avenue for returning veterans to transition into society and capitalizes on skills that made them successful in the military. However, these opportunities may be missed due to a lack of targeted training programs, guidance, and information for the veteran community. Programs directed toward educating beginning farmers, along with increased awareness and demand for local food production, have provided an opportunity for individuals interested in farming. However, few programs have focused on the needs of veterans interested in agriculture. Since 2007, our team has directly supported approximately 300 veterans interested in farming through workshops, internships, research, and training opportunities and an additional 650 veterans nationally through the Farmer Veteran Coalition. As more programs develop for veterans in agricultural disciplines, we believe lessons learned from our partnership with veterans may be beneficial to those working with this population of farmers

Method for bacteriophage delivery and amplification

Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods are disclosed. Also disclosed are: methods of treating a subject infected with a pathogenic bacterium using bacteriophage, of decontaminating objects using bacteriophage, and of producing vaccines. In another aspect, methods of determining bacterial viability and of improving the sensitivity of a biosensor using wide host range bacteriophages are also disclosed

Method for Bacteriophage Delivery and Amplification

Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected are described. In addition to methods of treating a subject infected with a pathogenic bacterium using bacteriophage, of decontaminating objects using bacteriophage, of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are also disclosed

B-factory Physics from Effective Supersymmetry

We discuss how to extract non-Standard Model effects from B-factory phenomenology. We then analyze the prospects for uncovering evidence for Effective Supersymmetry, a class of supersymmetric models which naturally suppress flavor changing neutral currents and electric dipole moments without squark universality or small CP violating phases, in experiments at BaBar, BELLE, HERA-B, CDF/D0 and LHC-B.Comment: 5 pages, 2 figures, revtex, eps

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

No abstract available

Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis

IntroductionIdiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF and a prior association of theHLA-DQB1gene with idiopathic fibrotic interstitial pneumonia (including IPF) has been reported. Due to the important role that the Human Leukocyte Antigen (HLA) region plays in the immune response, here we evaluated if HLA genetic variation was associated specifically with IPF risk.MethodsWe performed a meta-analysis of associations of the HLA region with IPF risk in individuals of European ancestry from seven independent case-control studies of IPF (comprising a total of 5159 cases and 27 459 controls, including the prior study of fibrotic interstitial pneumonia). Single nucleotide polymorphisms, classical HLA alleles and amino acids were analysed and signals meeting a region-wide association thresholdp<4.5×10−4and a posterior probability of replication >90% were considered significant. We sought to replicate the previously reportedHLA-DQB1association in the subset of studies independent of the original report.ResultsThe meta-analysis of all seven studies identified four significant independent single nucleotide polymorphisms associated with IPF risk. However, none met the posterior probability for replication criterion. TheHLA-DQB1association was not replicated in the independent IPF studies.ConclusionVariation in the HLA region was not consistently associated with risk in studies of IPF. However, this does not preclude the possibility that other genomic regions linked to the immune response may be involved in the aetiology of IPF

Paternity Efficiency in Turkeys Differes Extensively After Hererospermic Insemination

All commercial turkey hens in the U.S. are bred by artificial insemination (AI). Since semen samples are pooled from 10 or more males (heterospermic inseminations), paternity of the progeny is rarely known. Whereas it is known that sperm competition exists, the degree to which any male\u27s sperm fertilizes ova relative to other male\u27s remains unknown. In this work, we determined individual male fecundity relative to that of other males in the study and attempted to establish a relationship between male fecundity and semen characteristics in turkeys. Fingerprinting of genomic DNA from parents and offspring was used to determine parentage efficiency. This work demonstrated that relatively few toms sired a high percentage of the progeny. Of the 26 toms contributing to the pooled ejaculates, six (23%) sired more than 60% of the 145 poults. Conversely, 14 toms (54%) sired three or fewer poults. We found that the semen parameters evaluated, some of which are used routinely by the turkey industry, were not good at predicting paternity. Under the conditions of this study, the majority of the projeny were derived from semen from on or two toms after heterospermic inseminations