4,051 research outputs found

    The QUEST Data Processing Software Pipeline

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    A program that we call the QUEST Data Processing Software Pipeline has been written to process the large volumes of data produced by the QUEST camera on the Samuel Oschin Schmidt Telescope at the Palomar Observatory. The program carries out both aperture and PSF photometry, combines data from different repeated observations of the same portion of sky, and produces a Master Object Catalog. A rough calibration of the data is carried out. This program, as well as the calibration procedures and quality checks on the output are described.Comment: 17 pages, 1 table, 8 figure

    Background modeling by shifted tilings of stacked denoising autoencoders

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    The effective processing of visual data without interruption is currently of supreme importance. For that purpose, the analysis system must adapt to events that may affect the data quality and maintain its performance level over time. A methodology for background modeling and foreground detection, whose main characteristic is its robustness against stationary noise, is presented in the paper. The system is based on a stacked denoising autoencoder which extracts a set of significant features for each patch of several shifted tilings of the video frame. A probabilistic model for each patch is learned. The distinct patches which include a particular pixel are considered for that pixel classification. The experiments show that classical methods existing in the literature experience drastic performance drops when noise is present in the video sequences, whereas the proposed one seems to be slightly affected. This fact corroborates the idea of robustness of our proposal, in addition to its usefulness for the processing and analysis of continuous data during uninterrupted periods of time.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    On the Two q-Analogue Logarithmic Functions

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    There is a simple, multi-sheet Riemann surface associated with e_q(z)'s inverse function ln_q(w) for 0< q < 1. A principal sheet for ln_q(w) can be defined. However, the topology of the Riemann surface for ln_q(w) changes each time "q" increases above the collision point of a pair of the turning points of e_q(x). There is also a power series representation for ln_q(1+w). An infinite-product representation for e_q(z) is used to obtain the ordinary natural logarithm ln{e_q(z)} and the values of sum rules for the zeros "z_i" of e_q(z). For |z|<|z_1|, e_q(z)=exp{b(z)} where b(z) is a simple, explicit power series in terms of values of these sum rules. The values of the sum rules for the q-trigonometric functions, sin_q(z) and cos_q(z), are q-deformations of the usual Bernoulli numbers.Comment: This is the final version to appear in J.Phys.A: Math. & General. Some explict formulas added, and to update the reference

    Planning in the Eighties: A Special Report

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    This special report on the future of planning is a direct response to the wave of self-examination now underway for planning practitioners, academics and community groups. The young decade's tides of budget slashing, regulation cutting and reorganization have led many to reassess the mission of planning, planners' identities and approaches planners use to achieve their goals. Carolina Planning has asked a number of noted practitioners and academics in various fields of planning to sketch some impressions about planning in this decade. In the following report, the contributors view recent trends in substantive areas of planning practice, discuss the roles planners may ploy and the approaches planners may be taking. One major thread running through the pieces is the need for strong planning in a period of shrinking resources. Includes the following: Community Organizing, Self-Help, and Planning in the Eighties; Environmental Planning in the Eighties; Neighborhood Planning in the Eighties; Transportation Planning in the Eighties; Public Participation in the Eighties; North Carolina's Lead Regional Organizations in the Eighties; Human Services Planning in the Eightie

    Stationary solutions of the one-dimensional nonlinear Schroedinger equation: I. Case of repulsive nonlinearity

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    All stationary solutions to the one-dimensional nonlinear Schroedinger equation under box and periodic boundary conditions are presented in analytic form. We consider the case of repulsive nonlinearity; in a companion paper we treat the attractive case. Our solutions take the form of stationary trains of dark or grey density-notch solitons. Real stationary states are in one-to-one correspondence with those of the linear Schr\"odinger equation. Complex stationary states are uniquely nonlinear, nodeless, and symmetry-breaking. Our solutions apply to many physical contexts, including the Bose-Einstein condensate and optical pulses in fibers.Comment: 11 pages, 7 figures -- revised versio

    Evidence for diversifying selection of genetic regions of encoding putative collagen-like host-adhesive fibers in Pasteuria penetrans

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    © FEMS 2018. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Pasteuria spp. belong to a group of genetically diverse endospore-forming bacteria (phylum: Firmicutes) that are known to parasitize plant-parasitic nematodes and water fleas (Daphnia spp.). Collagen-like fibres form the nap on the surface of endospores and the genes encoding these sequences have been hypothesised to be involved in the adhesion of the endospores of Pasteuria spp. to their hosts. We report a group of 17 unique collagen-like genes putatively encoded by Pasteuria penetrans (strain: Res148) that formed five different phylogenetic clusters and suggest that collagen-like proteins are an important source of genetic diversity in animal pathogenic Firmicutes including Pasteuria. Additionally, and unexpectedly, we identified a putative collagen-like sequence which had a very different sequence structure to the other collagen-like proteins but was similar to the protein sequences in Megaviruses that are involved in host-parasite interactions. We, therefore, suggest that these diverse endospore surface proteins in Pasteuria are involved in biological functions, such as cellular adhesion; however, they are not of monophyletic origin and were possibly obtained de novo by mutation or possibly through selection acting upon several historic horizontal gene transfer events.Peer reviewedFinal Published versio

    Impact and cost-effectiveness of snail control to achieve disease control targets for schistosomiasis

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    Schistosomiasis is a parasitic disease that affects over 240 million people globally. To improve population-level disease control, there is growing interest in adding chemical-based snail control interventions to interrupt the lifecycle of Schistosoma in its snail host to reduce parasite transmission. However, this approach is not widely implemented, and given environmental concerns, the optimal conditions for when snail control is appropriate are unclear. We assessed the potential impact and cost-effectiveness of various snail control strategies. We extended previously published dynamic, age-structured transmission and cost-effectiveness models to simulate mass drug administration (MDA) and focal snail control interventions against Schistosoma haematobium across a range of low-prevalence (5-20%) and high-prevalence (25-50%) rural Kenyan communities. We simulated strategies over a 10-year period of MDA targeting school children or entire communities, snail control, and combined strategies. We measured incremental cost-effectiveness in 2016 US dollars per disability-adjusted life year and defined a strategy as optimally cost-effective when maximizing health gains (averted disability-adjusted life years) with an incremental cost-effectiveness below a Kenya-specific economic threshold. In both low- and high-prevalence settings, community-wide MDA with additional snail control reduced total disability by an additional 40% compared with school-based MDA alone. The optimally cost-effective scenario included the addition of snail control to MDA in over 95% of simulations. These results support inclusion of snail control in global guidelines and national schistosomiasis control strategies for optimal disease control, especially in settings with high prevalence, "hot spots" of transmission, and noncompliance to MDA

    Why Can't Rodents Vomit? A Comparative Behavioral, Anatomical, and Physiological Study

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    The vomiting (emetic) reflex is documented in numerous mammalian species, including primates and carnivores, yet laboratory rats and mice appear to lack this response. It is unclear whether these rodents do not vomit because of anatomical constraints (e.g., a relatively long abdominal esophagus) or lack of key neural circuits. Moreover, it is unknown whether laboratory rodents are representative of Rodentia with regards to this reflex. Here we conducted behavioral testing of members of all three major groups of Rodentia; mouse-related (rat, mouse, vole, beaver), Ctenohystrica (guinea pig, nutria), and squirrel-related (mountain beaver) species. Prototypical emetic agents, apomorphine (sc), veratrine (sc), and copper sulfate (ig), failed to produce either retching or vomiting in these species (although other behavioral effects, e.g., locomotion, were noted). These rodents also had anatomical constraints, which could limit the efficiency of vomiting should it be attempted, including reduced muscularity of the diaphragm and stomach geometry that is not well structured for moving contents towards the esophagus compared to species that can vomit (cat, ferret, and musk shrew). Lastly, an in situ brainstem preparation was used to make sensitive measures of mouth, esophagus, and shoulder muscular movements, and phrenic nerve activity-key features of emetic episodes. Laboratory mice and rats failed to display any of the common coordinated actions of these indices after typical emetic stimulation (resiniferatoxin and vagal afferent stimulation) compared to musk shrews. Overall the results suggest that the inability to vomit is a general property of Rodentia and that an absent brainstem neurological component is the most likely cause. The implications of these findings for the utility of rodents as models in the area of emesis research are discussed. © 2013 Horn et al

    Longitudinal Research on Aging Drivers (LongROAD): study design and methods

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    Background: As an important indicator of mobility, driving confers a host of social and health benefits to older adults. Despite the importance of safe mobility as the population ages, longitudinal data are lacking about the natural history and determinants of driving safety in older adults. Methods: The Longitudinal Research on Aging Drivers (LongROAD) project is a multisite prospective cohort study designed to generate empirical data for understanding the role of medical, behavioral, environmental and technological factors in driving safety during the process of aging. Results: A total of 2990 active drivers aged 65–79 years at baseline have been recruited through primary care clinics or health care systems in five study sites located in California, Colorado, Maryland, Michigan, and New York. Consented participants were assessed at baseline with standardized research protocols and instruments, including vehicle inspection, functional performance tests, and “brown-bag review” of medications. The primary vehicle of each participant was instrumented with a small data collection device that records detailed driving data whenever the vehicle is operating and detects when a participant is driving. Annual follow-up is being conducted for up to three years with a telephone questionnaire at 12 and 36 months and in-person assessment at 24 months. Medical records are reviewed annually to collect information on clinical diagnoses and healthcare utilization. Driving records, including crashes and violations, are collected annually from state motor vehicle departments. Pilot testing was conducted on 56 volunteers during March–May 2015. Recruitment and enrollment were completed between July 2015 and March 2017. Conclusions: Results of the LongROAD project will generate much-needed evidence for formulating public policy and developing intervention programs to maintain safe mobility while ensuring well-being for older adults

    Geographical Perspectives on Transport and Ageing

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    In terms of ageing, we are living in unprecedented times. People across the globe are living longer than ever before and societies are ageing at increasing rates. In low to middle income countries reductions in mortality at young ages have fuelled this growth. A person born today in Brazil, for example, can expect to live 20 years longer than someone born 50 years ago (WHO, 2015). For the first time life expectancy across the globe is over 60 years of age. In high Income countries, someone born now can expect to live up to around 80 years of age on average (ONS, 2015). There are not simply a growing number of older people, but also a growing number of older people as a total percentage of the population due to people living longer and declining birth rates in many countries. Across Europe, for example, people aged over 65 years will account for 29.5% of the population in 2060 compared to around 19% now (EUROSTAT, 2017). The share of those aged 80 years or above across Europe will almost triple by 2060 (EUROSTAT, 2017)The macro level demographics and associated trends mask big differences within the ageing populations. There can be as much as 10 years difference in life expectancy within high income countries, for example in the UK someone born a baby boy born in Kensington and Chelsea has a life expectancy of 83.3 years, compared with a boy born in Glasgow who has a life expectancy of 10 years lower (73.0 years) (ONS, 2015). For newborn baby girls, life expectancy is highest in Chiltern at 86.7 years and 8 years lower Glasgow at 78.5 years (ONS, 2015; NRS, 2016). There is also considerable variation within cities, spatially and socially.This volume brings together contributions from a broad range of human geographers, with different disciplinary perspectives of transport and ageing. This chapter outlines some of the key contemporary issues for an ageing society in terms of transport and mobility, highlights the importance of considering transport and mobility for ageing populations and outlines the contribution that a geographical approach can offer to studies of transport and ageing
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