Pengelompokkan dan Pemetaan Derajat Kesehatan Masyarakat Pada Tingkat Kelurahan Kota Lubuklinggau Dengan Metode FUZZY C-MEANS

Derajat kesehatan masyarakat adalah gambaran tentang kondisi kesehatan yang terjadi secara umum di masyarakat. Situasi derajat kesehatan suatu kota dipaparkan dalam profil kesehatan yang disusun setiap tahunnya. Kota Lubuklinggau terus berusaha meningkatkan derajat kesehatan masyarakatnya yang kemudian dipaparkan pada profil kesehatan Kota Lubuklinggau. Belum terdapat penjelasan mengenai pengelompokkan derajat kesehatan secara umum dari setiap daerah sesuai dengan nilai indikator-indikatornya. Pada penelitian ini dihasilkan pengelompokkan derajat kesehatan masyarakat kedalam 3 kategori, yaitu derajat kesehatan tertinggi, menengah, dan terendah. Fuzzy C-Means yang merupakan metode pengelompokkan data digunakan untuk mengelompokkan derajat kesehatan masyarakat. Pengelompokkan dilakukan menggunakan indikator derajat kesehatan masyarakat yang dipaparkan pada profil kesehatan sehingga menghasilkan kelompok-kelompok kelurahan berdasarkan derajat kesehatannya. Pada profil kesehatan, kondisi derajat kesehatan dijelaskan ditiap-tiap indikator tanpa mengetahui kondisi dari keseluruhan indikator-indikator tersebut. Setelah dilakukan pengelompokkan derajat kesehatan masyarakat pada tahun 2019, dari total 72 kelurahan diketahui terdapat 35 kelurahan termasuk kedalam kelompok menengah, 21 kelurahan termasuk kedalam kelompok tertinggi, dan 16 kelurahan termasuk kedalam kelompok terendah. Penelitian ini dapat membantu mengamati kondisi derajat kesehatan masyarakat pada tingkat kelurahan kota Lubuklinggau. Sehingga dapat memudahkan Dinas Kesehatan Kota Lubuklinggau dalam berupaya meningkatkan derajat kesehatan masyarakat kota Lubuklinggau

Obstructive jaundice secondary to pancreatic head adenocarcinoma in a young teenage boy: a case report

<p>Abstract</p> <p>Introduction</p> <p>Pancreatic adenocarcinoma is extremely rare in childhood. We report a case of metastatic pancreatic adenocarcinoma in a 13-year-old boy, revealed by jaundice.</p> <p>Case presentation</p> <p>A 13-year-old Moroccan boy was admitted with obstructive jaundice to the children's Hospital of Rabat, Department of Pediatric Oncology. Laboratory study results showed a high level of total and conjugated bilirubin. Computerized tomography of the abdomen showed a dilatation of the intra-hepatic and extra-hepatic bile ducts with a tissular heterogeneous tumor of the head of the pancreas and five hepatic lesions. Biopsy of a liver lesion was performed, and a histopathological examination of the sample confirmed the diagnosis of metastatic ductal adenocarcinoma of the pancreas. Our patient underwent a palliative biliary derivation. After that, chemotherapy was administered (5-fluorouracil and epirubicin), however no significant response to treatment was noted and our patient died six months after diagnosis.</p> <p>Conclusion</p> <p>Malignant pancreatic tumors, especially ductal carcinomas, are exceedingly rare in the pediatric age group and their clinical features and treatment usually go unappreciated by most pediatric oncologists and surgeons.</p

Effects of Chemical Sympathectomy on Contralateral Testicular Histology and Fertility in Unilateral Vasectomy

Unilateral obstruction or injury to the vas deferens can result in significant injury to the contralateral testicle. Although various pathways have been proposed, the mechanism of contralateral testicular deterioration remains controversial. The present animal study was performed to evaluate the effects of unilateral vasectomy on ipsilateral and contralateral testicular histology and fertility in rats that were chemically sympathectomized neonatally. The study comprised 40 male albino rats: 20 received a placebo and the other 20 underwent chemical sympathectomy neonatally. When 60 days old, each group of 20 rats was divided into two groups that underwent either a sham operation or an operation to create unilateral left vasectomy. Eight weeks after surgery, each male rat was housed with two known fertile female rats for 25 days, and then their testes were harvested. Mean seminiferous tubular diameters (MSTD) and mean testicular biopsy scores (MTBS) were determined for each testis. Although MSTD and MTBS were not significantly different between groups, chemical sympathectomy prevented the decrease in total fertility rates of the rats with unilateral left vasectomy in our study. Prevention of this decrease by chemical sympathectomy suggests that the sympathetic nervous system may play a role in the testicular degeneration associated with vasectomy

Volume CXIV, Number 4, November 7, 1996

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population.Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014.Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosis) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto's thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%.Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespa