3,523 research outputs found
Concept Mapping to Develop a Framework for Characterizing Electronic Data Capture (EDC) Systems
CTSAs have brought about a push to find better EDC systems, which facilitate translational research. Based on the data management needs of a specific clinical/translational research lab, concept mapping was used to create a framework to evaluate EDCs. After refinement based on a spiral model, including consultations with the UW CTSA and a survey of other CTSAs, the tool was used to characterize EDCs used at CTSA sites across the country
Terpenoid-Induced Feeding Deterrence and Antennal Response of Honey Bees
Multiple interacting stressors negatively affect the survival and productivity of managed honey bee colonies. Pesticides remain a primary concern for beekeepers, as even sublethal exposures can reduce bee immunocompetence, impair navigation, and reduce social communication. Pollinator protection focuses on pesticide application guidelines; however, a more active protection strategy is needed. One possible approach is the use of feeding deterrents that can be delivered as an additive during pesticide application. The goal of this study was to validate a laboratory assay designed to rapidly screen compounds for behavioral changes related to feeding or feeding deterrence. The results of this investigation demonstrated that the synthetic Nasonov pheromone and its terpenoid constituents citral, nerol, and geraniol could alter feeding behavior in a laboratory assay. Additionally, electroantennogram assays revealed that these terpenoids elicited some response in the antennae; however, only a synthetic Nasonov pheromone, citral, and geraniol elicited responses that differed significantly from control and vehicle detections
Improving Mechanical Ventilator Clinical Decision Support Systems with A Machine Learning Classifier for Determining Ventilator Mode
Clinical decision support systems (CDSS) will play an in-creasing role in
improving the quality of medical care for critically ill patients. However, due
to limitations in current informatics infrastructure, CDSS do not always have
com-plete information on state of supporting physiologic monitor-ing devices,
which can limit the input data available to CDSS. This is especially true in
the use case of mechanical ventilation (MV), where current CDSS have no
knowledge of critical ventilation settings, such as ventilation mode. To enable
MV CDSS to make accurate recommendations related to ventilator mode, we
developed a highly performant ma-chine learning model that is able to perform
per-breath clas-sification of 5 of the most widely used ventilation modes in
the USA with an average F1-score of 97.52%. We also show how our approach makes
methodologic improvements over previous work and that it is highly robust to
missing data caused by software/sensor error
The Quintuplet Cluster: Extended Structure and Tidal Radius
The Quintuplet star cluster is one of only three known young ( Myr)
massive (M M) clusters within pc of the Galactic
Center. In order to explore star cluster formation and evolution in this
extreme environment, we analyze the Quintuplet's dynamical structure. Using the
HST WFC3-IR instrument, we take astrometric and photometric observations of the
Quintuplet covering a field-of-view, which is times
larger than those of previous proper motion studies of the Quintuplet. We
generate a catalog of the Quintuplet region with multi-band, near-infrared
photometry, proper motions, and cluster membership probabilities for
stars. We present the radial density profile of candidate Quintuplet
cluster members with M out to pc from the cluster
center. A lower limit of pc is placed on the tidal radius,
indicating the lack of a tidal truncation within this radius range. Only weak
evidence for mass segregation is found, in contrast to the strong mass
segregation found in the Arches cluster, a second and slightly younger massive
cluster near the Galactic Center. It is possible that tidal stripping hampers a
mass segregation signature, though we find no evidence of spatial asymmetry.
Assuming that the Arches and Quintuplet formed with comparable extent, our
measurement of the Quintuplet's comparatively large core radius of
pc provides strong empirical evidence that young massive
clusters in the Galactic Center dissolve on a several Myr timescale.Comment: 25 pages (21-page main text, 4-page appendix), 18 figures, submitted
to Ap
Deconstructing and Reconstructing Identity: How Queer Liberation Organizations Deploy Collective Identities
The mainstream gay rights movement has made significant strides toward its agenda, at least in part due to the movement’s claim that it represents all the interests of all LGBTQ communities. However, a queer liberation movement (QLM) led by queer people of color and other marginalized LGBTQ people has existed alongside the mainstream movement since its inception. This movement pursues a radically different agenda and employs organizing strategies distinct from those of the mainstream movement, centering the interests of those LGBTQ people most often left behind by the mainstream agenda. This paper examines how the QLM negotiates and deploys collective identity in and through its work. Collective identity is explored in the context of existing LGBTQ social movement theory and points to how the QLM challenges and extends social movement theorizing regarding collective identity and use of identity as a site for organizing
The SDSS-2MASS-WISE Ten Dimensional Stellar Color Locus
We present the fiducial main sequence stellar locus traced by 10 photometric
colors observed by SDSS, 2MASS, and WISE. Median colors are determined using
1,052,793 stars with r-band extinction less than 0.125. We use this locus to
measure the dust extinction curve relative to the r-band, which is consistent
with previous measurements in the SDSS and 2MASS bands. The WISE band
extinction coefficients are larger than predicted by standard extinction
models. Using 13 lines of sight, we find variations in the extinction curve in
H, Ks, and WISE bandpasses. Relative extinction decreases towards Galactic
anti-center, in agreement with prior studies. Relative extinction increases
with Galactic latitude, in contrast to previous observations. This indicates a
universal mid-IR extinction law does not exist due to variations in dust grain
size and chemistry with Galactocentric position. A preliminary search for
outliers due to warm circumstellar dust is also presented, using stars with
high signal-to-noise in the W3-band. We find 199 such outliers, identified by
excess emission in Ks-W3. Inspection of SDSS images for these outliers reveals
a large number of contaminants due to nearby galaxies. Six sources appear to be
genuine dust candidates, yielding a fraction of systems with infrared excess of
0.120.05%.Comment: 11 pages, 10 figures, MNRAS Accepted. Tables 1 and 2 available
online: https://github.com/jradavenport/wise_locu
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Algorithms, Automation, and News
This special issue examines the growing importance of algorithms and automation in the gathering, composition, and distribution of news. It connects a long line of research on journalism and computation with scholarly and professional terrain yet to be explored. Taken as a whole, these articles share some of the noble ambitions of the pioneering publications on ‘reporting algorithms’, such as a desire to see computing help journalists in their watchdog role by holding power to account. However, they also go further, firstly by addressing the fuller range of technologies that computational journalism now consists of: from chatbots and recommender systems, to artificial intelligence and atomised journalism. Secondly, they advance the literature by demonstrating the increased variety of uses for these technologies, including engaging underserved audiences, selling subscriptions, and recombining and re-using content. Thirdly, they problematize computational journalism by, for example, pointing out some of the challenges inherent in applying AI to investigative journalism and in trying to preserve public service values. Fourthly, they offer suggestions for future research and practice, including by presenting a framework for developing democratic news recommenders and another that may help us think about computational journalism in a more integrated, structured manner
Research IT maturity models for academic health centers: Early development and initial evaluation
This paper proposes the creation and application of maturity models to guide institutional strategic investment in research informatics and information technology (research IT) and to provide the ability to measure readiness for clinical and research infrastructure as well as sustainability of expertise. Conducting effective and efficient research in health science increasingly relies upon robust research IT systems and capabilities. Academic health centers are increasing investments in health IT systems to address operational pressures, including rapidly growing data, technological advances, and increasing security and regulatory challenges associated with data access requirements. Current approaches for planning and investment in research IT infrastructure vary across institutions and lack comparable guidance for evaluating investments, resulting in inconsistent approaches to research IT implementation across peer academic health centers as well as uncertainty in linking research IT investments to institutional goals. Maturity models address these issues through coupling the assessment of current organizational state with readiness for deployment of potential research IT investment, which can inform leadership strategy. Pilot work in maturity model development has ranged from using them as a catalyst for engaging medical school IT leaders in planning at a single institution to developing initial maturity indices that have been applied and refined across peer medical schools
Terpenoid-Induced Feeding Deterrence and Antennal Response of Honey Bees
Multiple interacting stressors negatively affect the survival and productivity of managed honey bee colonies. Pesticides remain a primary concern for beekeepers, as even sublethal exposures can reduce bee immunocompetence, impair navigation, and reduce social communication. Pollinator protection focuses on pesticide application guidelines; however, a more active protection strategy is needed. One possible approach is the use of feeding deterrents that can be delivered as an additive during pesticide application. The goal of this study was to validate a laboratory assay designed to rapidly screen compounds for behavioral changes related to feeding or feeding deterrence. The results of this investigation demonstrated that the synthetic Nasonov pheromone and its terpenoid constituents citral, nerol, and geraniol could alter feeding behavior in a laboratory assay. Additionally, electroantennogram assays revealed that these terpenoids elicited some response in the antennae; however, only a synthetic Nasonov pheromone, citral, and geraniol elicited responses that differed significantly from control and vehicle detections
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