The Effect of Three Good Things Technique on Self-Leadership to Nursing Students

Background: Every nursing student must develop self-leadership skills. It has been proven that nursing students who score high in self-leadership would have better performance and self-efficacy. The Three Good Things intervention is a potential strategy for enhancing self-leadership. Aim: The aimed of the research was to identify the effect of the three nice things technique on nursing students' self-leadership. Method: This research is a quantitative study using a Quasi-Experimental design with Two Group Pre and Post-test, involving 60 nursing students as respondents. Data collection with the RSLQ questionnaire (Revised Self-Leadership Questionnaire) and data analysis using Paired Sample ANCOVA and T-Test Results: This study showed the picture of low self-leadership before intervention both in the control and intervention groups. Then after the intervention, the self-leadership was still low in the control group, while the intervention group showed a high self-leadership, then there was a significant difference in self-leadership between before and after the intervention in the intervention group with a p-value of 0.000 (p<0.05). There was no significant difference between the control before and after the intervention with a p-value of 0.335 (p>0.05). And the three good things intervention proved to have an effect on self-leadership in nursing students (p-value of 0.000). Conclusion: This study showed an effect of providing three good things interventions on self-leadership in nursing students. This research is expected for the institution to conduct training or workshops on self-leadership in maintaining the consistency of student self-leadership in the institution.  

Control of Transcription by Cell Size

Cell size increases significantly with increasing ploidy. Differences in cell size and ploidy are associated with alterations in gene expression, although no direct connection has been made between cell size and transcription. Here we show that ploidy-associated changes in gene expression reflect transcriptional adjustment to a larger cell size, implicating cellular geometry as a key parameter in gene regulation. Using RNA-seq, we identified genes whose expression was altered in a tetraploid as compared with the isogenic haploid. A significant fraction of these genes encode cell surface proteins, suggesting an effect of the enlarged cell size on the differential regulation of these genes. To test this hypothesis, we examined expression of these genes in haploid mutants that also produce enlarged size. Surprisingly, many genes differentially regulated in the tetraploid are identically regulated in the enlarged haploids, and the magnitude of change in gene expression correlates with the degree of size enlargement. These results indicate a causal relationship between cell size and transcription, with a size-sensing mechanism that alters transcription in response to size. The genes responding to cell size are enriched for those regulated by two mitogen-activated protein kinase pathways, and components in those pathways were found to mediate size-dependent gene regulation. Transcriptional adjustment to enlarged cell size could underlie other cellular changes associated with polyploidy. The causal relationship between cell size and transcription suggests that cell size homeostasis serves a regulatory role in transcriptome maintenance.National Institutes of Health (U.S.) (grant GM035010)National Institutes of Health (U.S.) (grant GM040266

Hubungan Antara Bersyukur Dengan Prososial Pada Pelaku Umkm Di Masa Pandemi Covid 19

The COVID-19 pandemic has had an impact on Micro, Small and Medium Enterprises (MSMEs). Prosocial behavior from fellow business perpetractor was important to overcome these impacts. Gratitude provides positive emotions so that it can encourage individuals to behave well and lead to prosocial behavior. The purpose of this study was to examine the relationship between gratitude and prosocial behavior in MSME perpetractor during the covid 19 pandemic. The sample in this study was 100 MSME perpetractor with purposive sampling using a purposive sampling technique. Data were collected using a gratitude scale and prosocial behavior. Data analysis was performed using product moment correlation analysis. The results of this study indicate the value of r (correlation coefficient) of 0.649 and a significance value (p) of 0.000 (p <0.05). The conclusion in this study is that there is a significant positive relationship between gratitude and prosocial behavior

Effectiveness of the AngoLingo Mobile Game Technology in English Language Learning in Adamson University Basic Education Department

Technology is gradually shifting the focus of learning to less traditional methods; like eBooks, audiobooks, and more recently, mobile applications. This shift indicates an apparent need to incorporate entertaining components into learning tools to keep users engaged in critical thinking, and comprehension activities. There is untapped power in mobile entertainment, particularly mobile games that can and must be harnessed to improve current methods, and even introduce new methods of learning English. This study seeks to determine the effectiveness of AngloLingo, a mobile game that is built on the basics of English, in facilitating learning of English vocabulary, spelling and grammar in students in the Basic Education Department of Adamson University, Philippines. A control group (N=18) and an experimental group (N=18), were used during the test. Quasi-Experimental Research Design with pretest and posttest was used to determine the difference in performance between the control and experimental groups. Results indicate a significant improvement in performance on the post-test of the experimental group due to the use of AngloLingo before administration of the posttest. The overall results of the three sub-tests (P-Value = 6.39E-08) indicate the effectiveness of AngloLingo in learning Basic English vocabulary, spelling, and grammar. This study also offers recommendations on the incorporation of mobile games in teaching and learning Basic English

Repeated cleavage failure does not establish centrosome amplification in untransformed human cells

Transient cleavage failure in dividing cells is not sufficient to establish stable populations of cells with extra centrosomes

Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution

The ability of an organism to replicate and segregate its genome with high fidelity is vital to its survival and for the production of future generations. Errors in either of these steps (replication or segregation) can lead to a change in ploidy or chromosome number. While these drastic genome changes can be detrimental to the organism, resulting in decreased fitness, they can also provide increased fitness during periods of stress. A change in ploidy or chromosome number can fundamentally change how a cell senses and responds to its environment. Here, we discuss current ideas in fungal biology that illuminate how eukaryotic genome size variation can impact the organism at a cellular and evolutionary level. One of the most fascinating observations from the past 2 decades of research is that some fungi have evolved the ability to tolerate large genome size changes and generate vast genomic heterogeneity without undergoing canonical meiosis

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing cells up to 100 µm. These morphological changes in cell size affected pathogenicity via reducing phagocytosis by host mononuclear cells, increasing resistance to oxidative and nitrosative stress, and correlated with reduced penetration of the central nervous system. Cell enlargement was stimulated by coinfection with strains of opposite mating type, and ste3aΔ pheromone receptor mutant strains had reduced cell enlargement. Finally, analysis of DNA content in this novel cell type revealed that these enlarged cells were polyploid, uninucleate, and produced daughter cells in vivo. These results describe a novel mechanism by which C. neoformans evades host phagocytosis to allow survival of a subset of the population at early stages of infection. Thus, morphological changes play unique and specialized roles during infection

Academic and Social Adjustment of Students Transitioning from an Early College High School Program to an Institution of Higher Education

Historically, minority and low-income populations have faced numerous challenges in achieving a higher education particularly students of Latino descent. Gandara and Contreras (2009) explain that Latinos are the fastest growing population in the United States and yet academically, they are further behind than any other ethnic group in the nation. However, as the nation continues to grapple with how best to educate its children, and programs such as early college high schools grow in popularity, a viable solution to closing the academic achievement gaps of minority students, it is more important than ever that there is an understanding of how these programs impact students\u27 academic and social adjustment to a four-year institution. Although designed to reduce time to degree and remove significant financial barriers to obtaining a college degree, the question as to whether early college high schools are preparing students well enough for the eventual academic and social adjustment to a four-year institution is a relevant one. This study examined the academic and social adjustment of students who participated in an early college high school and matriculated to a four-year, public, research institution after completing 60 hours of college coursework thus academically classified as juniors as compared to students who had attended a traditional high school, matriculated to the four-year, pubic institution as freshman and at the time of the study were classified as juniors

A training framework for the Department of Defense public key infrastructure

Increased use of the Internet and the growth of electronic commerce within the Department of Defense (DoD) has led to the development and implementation of the DoD Public Key Infrastructure (PKI). Any PKI can only serve its intended purpose if there is trust within the system. This thesis reviews the basics of public (or asymmetric) key cryptography and its counterpart, symmetric key cryptography. It outlines the DoDαs PKI implementation plan and the user roles identified within the infrastructure. Because a PKI relies entirely on trust, training for all users of a PKI is essential. The current approach to PKI training within the DoD will not provide all of its users with the required level of understanding of the system as a whole, or of the implications and ramifications that their individual actions may have upon the system. The decentralized, segmented, and inconsistent approach to PKI training will result in a lack of trust within the PKI. Training for the DoD PKI must be consistent, current, appropriate, and available to all users at any time. The author proposes a web-based training framework for the DoD PKI. The basic requirements and design of the framework are presented, and a prototype is developed for further testing and evaluation. Without the proper attention to training, the DoD PKI will be at risk, and may not perform its intended functions of providing the required authenticity and integrity across the various networks upon which DoD conducts business.http://archive.org/details/atrainingframewo109453826US Navy (USN) autho