A Unique Case of Hepatocellular Carcinoma Treated with Radiofrequency Ablation with More than 12 Years Overall Survival: A Case Report

The case of a 72-year-old male patient with HCC is presented in whom percutaneous RFA was used as the sole first-line anticancer treatment, since he denied having partial hepatectomy. The patient underwent RFA two more times, at 1.5 years for treating a local tumor progression at the initial ablation site and at 11 years after the first session for treating a new remote intrahepatic recurrence. He revealed a long-term survival of more than 12 years so far and still remains in excellent clinical status

Experimental uncertainty budget for concrete compressive strength test based on a multifactorial analysis

The objective of the study is to introduce an experimental un­cer­tainty budget process for concrete compressive strength test, based on a pro­to­col that incorporates effects of multiple factors significant for the measure­ment result. The proposed procedure is rather useful for laboratories seeking accreditation according to ISO/IEC 17025, in order to emphasize the contri­bu­tion of type A uncertainty estimations, rather than relying on type B estimations that are unable to address the correlation between those factors. Two indepen­dent experiments were performed. Experiment I is proposed as a simple, suit­ably designed, reproducibility trial for laboratories performing EN 12390 test method, i.e. when a specified nominal curing age is targeted, following experi­mental design on multiple uncertainty parameters. A sensitivity analysis was introduced based on a semi-empirical multifactorial regression model (experi­ment II) for concrete compressive strength as a function of specimen’s curing age and W/C ratio. The present study is an effort towards an integrated and standardized method for experimental, semi-empirical multifactorial re­gression estimation of the uncertainty budget for the EN 12390 test method, being useful, also, as a baseline for internal quality control programs when ad­justed for the specific characteristics of concrete specimens tested by a laboratory

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Oppressive retention of dividends and minority protection in closed corporations: the French approach

International audienc

L’ESMA et la sanction de Fitch : brèves réflexions sur les pouvoirs de surveillance de l’Autorité européenne des marchés financier

International audienc

Brèves réflexions sur la réglementation des monnaies virtuelles

National audienc

Bitcoin and Challenges for Financial Regulation

International audienc

Reflections on CCP resolution tools, Seventh German-French Symposium on Company Law and Capital Markets Law

International audienc

Dette sociale et responsabilité des associés d’une SNC

Note sous Cass. 2e civ.International audienc