125 research outputs found

    El género en la derecha radical populista del sur de Europa

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    Abstract de una comunicación en congresoEste artículo tiene como objetivo analizar el discurso sobre el género de la derecha radical en los países del sur de Europa, en concreto, en España y Portugal. Investigaciones previas muestran que los asuntos de género y sexualidad son una problemática más bien secundaria para la derecha radical en los países del norte de Europa. Esta familia de partidos tiende a centrarse más bien en asuntos relacionados con la soberanía nacional, la ley y la seguridad y, sobre todo, la inmigración. En los últimos años, sin embargo, los asuntos de género están ganando importancia para estos actores políticos, especialmente, en el ámbito de la inmigración y el multiculturalismo. En este contexto, los partidos de derecha radical no muestran siempre un perfil conservador, sino que utilizan en ocasiones argumentos “liberales” sobre la igualdad de género y la libertad sexual para atacar a los inmigrantes no occidentales, sobre todo, de origen musulmán. Esta es la tendencia identificada en la derecha radical de los países del norte de Europa. Este artículo busca comprobar hasta qué punto estos marcos discursivos son aplicables a la derecha radical en el sur de Europa o si, por el contrario, se pueden identificar encuadres específicos en una región donde la brecha de género es mayor en términos comparados. Para ello, se han analizado las publicaciones de los principales partidos de derecha radical de España y Portugal en Facebook

    Población y actividades económicas de las comunidades asiáticas en España

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    Conté: Parte I: La población asiática en España : distribución geográfica y actividad empresarial / Joaquín Beltrán Antolín y Amelia Sáiz López -- Parte II: Comunidades asiáticas en Cataluña. Concentración y dispersión de su asentamiento y de sus actividades empresariales / Joaquín Beltrán Antolín y Amelia Sáiz López -- Parte III: Empresariado asiático en la Comunidad de Madrid / Débora Betrisey Nadali -- Parte IV: Las comunidades asiáticas en el archipiélago canario / Ana María López SalaDespués de los estudios Comunidades asiáticas en España y La internacionalización de la educación superior. Estudiantes asiáticos en Cataluña, este documento completa una línea de investigación impulsada por el Programa Asia de la Fundación CIDOB con la idea de superar la falta de conocimientos sobre estos colectivos. En este contexto, se presenta una aproximación en la distribución de la población de las principales comunidades asiáticas en España, con especial atención a su establecimiento en las comunidades autónomas de Cataluña, Madrid y Canarias y, especialmente, a la localización de sus actividades económicas. La globalización y el transnacionalismo constituyen el telón de fondo de esta investigación, ya que la hipótesis de partida es la conexión entre las actividades empresariales de los grupos establecidos en España y las de los que están en diáspora en otros lugares del mundo

    Constructing a Global and Integral Model of Business Management Using a CBR System

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    Knowledge has become the most strategic resource in the new business environment. A case-based reasoning system, which incorporates a novel clustering and retrieval method, has been developed for identifying critical situations in business processes. The proposed method is based on a Cooperative Maximum Likelihood Hebbian Learning model, which can be used to categorize the necessities for the Acquisition, Transfer and Updating of Knowledge of the different departments of a firm. This technique is used as a tool to develop a part of a Global and Integral Model of business Management, which brings about a global improvement in the firm, adding value, flexibility and competitiveness. From this perspective, the model tries to generalise the hypothesis of organizational survival and competitiveness, so that the organisation that is able to identify, strengthen, and use key knowledge will reach a pole position

    Insights into speleothems from lava tubes of the Galapagos Islands (Ecuador): mineralogy and biogenecity

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    Different types of hard and soft speleothems (stalactites, stalagmites, columns, crusts, flowstones, micro-gours and botryoidal coralloids) have been observed throughout lava tubes in the Galapagos archipelago, Ecuador. Three lava tubes were studied in this work: Gallardo and Royal Palm volcanic caves (Santa Cruz Island) and Sucre Cave (Isabela Island). The studied speleothems were mainly formed by opal, calcite and clay minerals, including plagioclase and pyroxenes from the basaltic host rock. Rarely, iron oxides, gypsum were found in some speleothems, which were interpreted as alteration products of the primary volcanic materials. Field emission scanning electron microscopy revealed abundant filamentous 17th International Vulcanspeleology Symposium 2 bacteria, and reticulated filaments similar to those recently observed in others lava tubes around the world. These filaments are associated with EPS and mineral deposits rich in Si, Ca or Fe. The identified minerals and the evidence of biosignatures suggest a biological contribution to speleothem development within Gallardo, Royal Palm and Sucre lava tubes

    Combined Genome, Transcriptome and Metabolome Analysis in the Diagnosis of Childhood Cerebellar Ataxia

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    Supplementary Materials: Supplementary Materials can be found at https://www.mdpi.com/1422 -0067/22/6/2990/s1.The project was approved by the Biomedical Research Ethics Committee of the Andalusian Public Health System in Granada, Spain on Oct. 29, 2015, (project identification code AP163052016). Data recording, sample collection and all in vitro experiments were conducted in accordance with ethical guidelines following the Nuremberg Code, Belmont Report, and the Declaration of Helsinki.Acknowledgments: We are grateful for the support and cooperation of the subjects, as well as their families.Ataxia in children is a common clinical sign of numerous neurological disorders consisting of impaired coordination of voluntary muscle movement. Its most common form, cerebellar ataxia, describes a heterogeneous array of neurologic conditions with uncountable causes broadly divided as acquired or genetic. Numerous genetic disorders are associated with chronic progressive ataxia, which complicates clinical management, particularly on the diagnostic stage. Advances in omics technologies enable improvements in clinical practice and research, so we proposed a multi-omics approach to aid in the genetic diagnosis and molecular elucidation of an undiagnosed infantile condition of chronic progressive cerebellar ataxia. Using whole-exome sequencing, RNA-seq, and untargeted metabolomics, we identified three clinically relevant mutations (rs141471029, rs191582628 and rs398124292) and an altered metabolic profile in our patient. Two POLR1C diagnostic variants already classified as pathogenic were found, and a diagnosis of hypomyelinating leukodystrophy was achieved. A mutation on the MMACHC gene, known to be associated with methylmalonic aciduria and homocystinuria cblC type, was also found. Additionally, preliminary metabolome analysis revealed alterations in our patient’s amino acid, fatty acid and carbohydrate metabolism. Our findings provided a definitive genetic diagnosis reinforcing the association between POLR1C mutations and hypomyelinating leukodystrophy and highlighted the relevance of multi-omics approaches to the disease.Fundación Mutua Madrileña, Spain XIII Call on Research Grants 2016, reference number AP16305201

    Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits

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    BACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. METHOD: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. RESULTS: 1.885 patients diagnosed with an Affective Disorder (n=1512) and Schizophrenia/ Schizoaffective Disorder (n=373) were included. In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. LIMITATIONS: The number of papers included in this review is limited to the few studies using non-attempter clinically-matched control group and therefore results regarding diagnosis, symptomatology and time of the attempt are modest and contradictory. CONCLUSIONS: Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide.This work was supported by Carlos III Health Research Institute[grant numbers PI14/02029, PI15/00793, PI15/00789, PI16/01164,PI17/01433 and PI18/01055 (co-financed by the European RegionalDevelopment Fund(FEDER/ERDF)/European Social Fund‘Investing inyour future’ and the Government of the Principality of Asturias PCTI-2018–2022 IDI/2018/235)], Foundation for Health Innovation andResearch (BIOEF); Bioaraba Research Institute; Networking Center forBiomedical Research in Mental Health (CIBERSAM), the BasqueGovernment [grant numbers 2015111024, 2017111104] and theUniversity of the Basque Country [grant number 321212ELBY]. Thepsychiatric research department in Araba University Hospital is sup-portedbytheStanleyResearchFoundation[grantnumber03-RC-003

    Tratamiento psicológico integrado de pacientes esquizofrénicos

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    El presente estudio se ha realizado con 35 esquizofrénicos (20 pacientes de un grupo de intervención y 15 de un grupo control). Todos los sujetos fueron asignados aleatoriamente a uno de dichos grupos. Los pacientes del grupo experimental fueron sometidos durante un año a un paquete integrado de intervención psicológica, que incluyó cuatro módulos de la IPT (Brenner et al., 1994), así como a sesiones de psicoeducación y terapia conductual. Al mismo tiempo, sus familiares también recibieron un programa de psicoeducación y entrenamiento conductual. Los pacientes del grupo control recibieron el tratamiento ambulatorio estándar para la esquizofrenia. Se compararon ambos grupos con medidas pre-post tratamiento, a partir de los datos obtenidos al inicio y final de la terapia. El análisis de las medias de las medidas clínicas y familiares revelaron que el grupo de intervención clínica experimentó una mejoría mucho mayor que el grupo control

    The deterioration of Circular Mausoleum, Roman Necropolis of Carmona, Spain

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    The Circular Mausoleum tomb in the Roman Necropolis of Carmona was carved on a calcarenite sequence in an ancient quarry located in the town of Carmona, Southern Spain. This rock-cut tomb, representative of Roman burial practices, currently suffers from serious deterioration. A detailed survey over several years permitted the identification of the main tomb's pathologies and damaging processes, which include loss of material (scaling, flaking, granular disintegration), surface modifications (efflorescences, crusts and deposits) and extensive biological colonization. The results obtained in this study indicated that anthropogenic changes were largely responsible and enhanced the main alteration mechanisms observed in the Circular Mausoleum. Based on the deterioration diagnosis, effective corrective actions were proposed. This study shows that any conservative intervention in the interior of the tomb should be preceded by accurate in situ measurements and laboratory analyses to ascribe the source of the deterioration damages and thus designing effective treatments.This research was funded by the Consejeria de Cultura, Junta de Andalucia, the Spanish Ministry of Science and Innovation project CGL2010-17183, and the program Torres Quevedo (PTQ 13-06296 and PTQ 12-05601)

    Zein-based nanospheres and nanocapsules for the encapsulation and oral delivery of quercetin

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    In this study, the ability of zein nanospheres (NS) and zein nanocapsules containing wheat germ oil (NC) to enhance the bioavailability and efficacy of quercetin was evaluated. Both types of nanocarriers had similar physico-chemical properties, including size (between 230 and 250 nm), spherical shape, negative zeta potential, and surface hydrophobicity. However, NS displayed a higher ability than NC to interact with the intestinal epithelium, as evidenced by an oral biodistribution study in rats. Moreover, both types of nanocarriers offered similar loading efficiencies and release profiles in simulated fluids. In C. elegans, the encapsulation of quercetin in nanospheres (Q-NS) was found to be two twice more effective than the free form of quercetin in reducing lipid accumulation. For nanocapsules, the presence of wheat germ oil significantly increased the storage of lipids in C. elegans; although the incorporation of quercetin (Q-NC) significantly counteracted the presence of the oil. Finally, nanoparticles improved the oral absorption of quercetin in Wistar rats, offering a relative oral bioavailability of 26% and 57% for Q-NS and Q-NC, respectively, compared to a 5% for the control formulation. Overall, the study suggests that zein nanocarriers, particularly nanospheres, could be useful in improving the bioavailability and efficacy of quercetin
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