Viruses and Drug Resistant Bacteria in Groundwater of Southeastern Minnesota

ABSTRACT-Karst topography of soils in southeastern Minnesota is responsible for the formation of sinkholes, subsurface cracks, and underground rivers which may enhance the transportation of surface contaminants into groundwater. The present study was conducted to determine the presence of human pathogenic viruses, coliforms, fecal coliforms and coliphages in private rural wells of this area. The occurrence of drug resistance in bacteria isolated from groundwater also was studied. Coliform bacteria were detected at least once from 22 of the 26 sites sampled over 34 months. Water from 10 sites yielded drug-resistant indicator bacteria; 25 of 38 (65.8 percent) total coliforms and 9 of27 (33.3 percent) fecal coliforms tested were found to carry drug resistance. Human enteric viruses were detected by DNA hybridization and/or virus isolation techniques in nine samples from seven different sites, some in the absence of fecal coliforms. Of the 161 samples tested for coliphages, 13 samples from seven sites were found positive. On two occasions, coliphages were isolated from samples in which coliforms were absent. These findings indicate that potential public health problems exist in this region

The effect of space-charge and wake fields in the Fermilab Booster

We calculate the impedance and the wake functions for laminated structures with parallel-planes and circular geometries. We critically examine the approximations used in the literature for the coupling impedance in laminated chambers and find that most of them are not justified because the wall surface impedance is large. A comparison between the flat and the circular geometry impedance is presented. We use the wake fields calculated for the Fermilab Booster laminated magnets in realistic beam simulations using the Synergia code. We find good agreement between our calculation of the coherent tune shift at injection energy and the experimental measurements. In this paper we calculate the impedance and the wake functions for laminated structures with parallel-planes and circular geometries. First the coupling impedance is derived as a function of the wall surface impedance. Then the surface impedance is calculated by solving Maxwell's equations inside the lamination and the crack regions. We find that the commonly used resistive-wall approximations, good for metallic pipes with small surface impedance, are not valid in the laminated structures where the surface impedance is large. Realistic Synergia simulations of the Booster machine with wake fields predict transverse coherent tune shifts in good agreement with the experiment

Iceberg calving during transition from grounded to floating ice: Columbia Glacier, Alaska

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95521/1/grl27053-sup-0003-fs02.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/95521/2/grl27053-sup-0002-fs01.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/95521/3/grl27053-sup-0005-txts01.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/95521/4/grl27053.pd

Reconciling Neutralino Relic Density with Yukawa Unified Supersymmetric Models

Supersymmetric grand unified models based on the gauge group SO(10) are especially attractive in light of recent data on neutrino masses. The simplest SO(10) SUSY GUT models predict unification of third generation Yukawa couplings in addition to the usual gauge coupling unification. Recent surveys of Yukawa unified SUSY GUT models predict an inverted scalar mass hierarchy in the spectrum of sparticle masses if the superpotential mu term is positive. In general, such models tend to predict an overabundance of dark matter in the universe. We survey several solutions to the dark matter problem in Yukawa unified supersymmetric models. One solution-- lowering the GUT scale mass value of first and second generation scalars-- leads to u_R and c_R squark masses in the 90-120 GeV regime, which should be accessible to Fermilab Tevatron experiments. We also examine relaxing gaugino mass universality which may solve the relic density problem by having neutralino annihilations via the Z or h resonances, or by having a wino-like LSP.Comment: 21 page file plus 9 figures; updated version to coincide with published versio

Evolutionary connectionism: algorithmic principles underlying the evolution of biological organisation in evo-devo, evo-eco and evolutionary transitions

The mechanisms of variation, selection and inheritance, on which evolution by natural selection depends, are not fixed over evolutionary time. Current evolutionary biology is increasingly focussed on understanding how the evolution of developmental organisations modifies the distribution of phenotypic variation, the evolution of ecological relationships modifies the selective environment, and the evolution of reproductive relationships modifies the heritability of the evolutionary unit. The major transitions in evolution, in particular, involve radical changes in developmental, ecological and reproductive organisations that instantiate variation, selection and inheritance at a higher level of biological organisation. However, current evolutionary theory is poorly equipped to describe how these organisations change over evolutionary time and especially how that results in adaptive complexes at successive scales of organisation (the key problem is that evolution is self-referential, i.e. the products of evolution change the parameters of the evolutionary process). Here we first reinterpret the central open questions in these domains from a perspective that emphasises the common underlying themes. We then synthesise the findings from a developing body of work that is building a new theoretical approach to these questions by converting well-understood theory and results from models of cognitive learning. Specifically, connectionist models of memory and learning demonstrate how simple incremental mechanisms, adjusting the relationships between individually-simple components, can produce organisations that exhibit complex system-level behaviours and improve the adaptive capabilities of the system. We use the term “evolutionary connectionism” to recognise that, by functionally equivalent processes, natural selection acting on the relationships within and between evolutionary entities can result in organisations that produce complex system-level behaviours in evolutionary systems and modify the adaptive capabilities of natural selection over time. We review the evidence supporting the functional equivalences between the domains of learning and of evolution, and discuss the potential for this to resolve conceptual problems in our understanding of the evolution of developmental, ecological and reproductive organisations and, in particular, the major evolutionary transitions

Soil water improvements with the long-term use of a winter rye cover crop

AbstractThe Midwestern United States, a region that produces one-third of maize and one-quarter of soybean grain globally, is projected to experience increasing rainfall variability. One approach to mitigate climate impacts is to utilize crop and soil management practices that enhance soil water storage and reduce the risks of flooding as well as drought-induced crop water stress. While some research indicates that a winter cover crop in maize-soybean rotations increases soil water availability, producers continue to be concerned that water use by cover crops will reduce water for a following cash crop. We analyzed continuous in-field soil water measurements from 2008 to 2014 at a Central Iowa research site that has included a winter rye cover crop in a maize-soybean rotation for thirteen years. This period of study included years in the top third of the wettest on record (2008, 2010, 2014) as well as drier years in the bottom third (2012, 2013). We found the cover crop treatment to have significantly higher soil water storage at the 0–30cm depth from 2012 to 2014 when compared to the no cover crop treatment and in most years greater soil water content on individual days analyzed during the cash crop growing season. We further found that the cover crop significantly increased the field capacity water content by 10–11% and plant available water by 21–22%. Finally, in 2013 and 2014, we measured maize and soybean biomass every 2–3 weeks and did not see treatment differences in crop growth, leaf area or nitrogen uptake. Final crop yields were not statistically different between the cover and no cover crop treatment in any of the seven years of this analysis. This research indicates that the long-term use of a winter rye cover crop can improve soil water dynamics without sacrificing cash crop growth in maize-soybean crop rotations in the Midwestern United States

Quality improvement in small office settings: an examination of successful practices

<p>Abstract</p> <p>Background</p> <p>Physicians in small to moderate primary care practices in the United States (U.S.) (<25 physicians) face unique challenges in implementing quality improvement (QI) initiatives, including limited resources, small staffs, and inadequate information technology systems 23,36. This qualitative study sought to identify and understand the characteristics and organizational cultures of physicians working in smaller practices who are actively engaged in measurement and quality improvement initiatives.</p> <p>Methods</p> <p>We undertook a qualitative study, based on semi-structured, open-ended interviews conducted with practices (N = 39) that used performance data to drive quality improvement activities.</p> <p>Results</p> <p>Physicians indicated that benefits to performing measurement and QI included greater practice efficiency, patient and staff retention, and higher staff and clinician satisfaction with practice. Internal facilitators included the designation of a practice champion, cooperation of other physicians and staff, and the involvement of practice leaders. Time constraints, cost of activities, problems with information management and or technology, lack of motivated staff, and a lack of financial incentives were commonly reported as barriers.</p> <p>Conclusion</p> <p>These findings shed light on how physicians engage in quality improvement activities, and may help raise awareness of and aid in the implementation of future initiatives in small practices more generally.</p