Clinicopathological study of oral focal mucinosis : a retrospective case series

Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology that exhibits tumor-like growth. It is considered the oral counterpart of cutaneous focal mucinosis or cutaneous myxoid cyst. This is a retrospective study of oral OFM diagnosed over a period of 42 years at an oral pathology service. Clinical, histopathological and immunohistochemical data were analyzed. Alcian blue staining and S-100 immunohistochemistry were performed. Eleven cases were retrieved (4:1 female-to-male ratio). The mean age was 44 years. The gingiva was the most affected site. The main clinical presentation was sessile or pedunculated lesions of fibrous or hyperplasic appearance, most of them asymptomatic. Positive Alcian blue staining and absence of S-100 protein were observed in all specimens, which supported the histological diagnosis of OFM. Surgical excision was the treatment of choice. Although rare, this study supports the inclusion of OFM in the differential diagnosis of intraoral myxoid lesions

Epidemiologic study of odontogenic and non-odontogenic cysts in children and adolescents of a Brazilian population

The objective of this study was to describe the frequency of cystic lesions in a Brazilian population of patients histopathologically diagnosed in the first and second decade of life. Retrospective descriptive cross-sectional study was performed. Biopsy records were obtained from the archives of a Brazilian referral center between 1980 and 2016. A total of 2.114 biopsy records of pediatric patients were analyzed with oral and maxillofacial lesions. Data such as gender, age, anatomical location, and histopathological diagnosis were collected and categorized. Among all oral and maxillofacial lesions (n=2.114), were diagnosed 294 cases of odontogenic cysts (13.9%) and 16 cases of non-odontogenic cysts (0.8%). The most frequent lesions in each group were, respectively: radicular cyst (n=145) and epidermoid cyst (n=4). These lesions were most common in female (n=158), with a mean age of 14 years. For intraosseous lesions, the mandible (n=148) was the most affected anatomic site; moreover, the floor of the mouth (n=6) was most affected by cysts in soft tissues. Odontogenic cysts were relatively common in population studied, but non-odontogenic cysts were rare in these patients

Desordens orais potencialmente malignas: uma análise bibliométrica dos trabalhos apresentados na Sociedade Brasileira de Pesquisa Odontológica (SBPqO)

Aim Oral Potentially Malignant Disorders (OPMDs) are lesions and epithelial conditions that present an increased risk of malignancy. In this research, the aim was to identify the profile of Brazilian scientific production on DOPMs, based on a bibliometric analysis of the works presented at the Meetings of the Brazilian Dental Research Society (SBPqO). Materials and Methods: a bibliometric study was carried out, in which the annals of the annual SBPqO meetings held between 2015 and 2019 were analyzed. Abstracts about DOPMs presented in any category were included and the following information was extracted: year, study design, type of DOPM, federative unit, location and educational institution of origin. The data were analyzed using descriptive statistics. Results: 91 abstracts were identified. Most were published in 2015 (24.2%) and by authors from the state of São Paulo (22%). Leukoplakia was the most frequent disorder (36.2%), followed by actinic cheilitis (35.2%). Most of the studies were authored by researchers from the Southeast (29%) and South (28%) regions. Regarding the educational institution, a large part (68.1%) came from public universities. The most frequent type of study was basic laboratory research (57.1%). Discussion: the study findings indicate that the number of researches on DOPMs presented at the SBPqO Meetings is still small, concentrated in the Southeast region and in public universities. Conclusion: conducting new research on this topic is very important, as it allows the discovery of information relevant to the health of individuals in the face of this neoplasm.  Objetivo: as Desordens Orais Potencialmente Malignas (DOPMs) consistem em lesões e condições epiteliais que apresentam risco aumentado de malignidade. Nessa pesquisa, buscou-se identificar o perfil da produção científica brasileira sobre as DOPMs, a partir de uma análise bibliométrica dos trabalhos apresentados nas Reuniões da Sociedade Brasileira de Pesquisa Odontológica (SBPqO). Materiais e Métodos: foi realizado um estudo bibliométrico, em que foram analisados os anais das reuniões anuais da SBPqO realizadas entre 2015 a 2019. Incluiu-se resumos sobre DOPMs apresentados em qualquer categoria e as seguintes informações foram extraídas: ano, desenho do estudo, tipo de DOPM, unidade federativa, localização e instituição de ensino superior de origem. Os dados foram analisados por meio de estatística descritiva.  Resultados: foram identificados 91 resumos. A maior parte foi publicada em 2015 (24,2%) e por autores do estado de São Paulo (22%). A leucoplasia foi a desordem mais frequente (36,2%), seguida pela queilite actínica (35,2%). A maioria dos estudos foi de autoria de pesquisadores das regiões Sudeste (29%) e Sul (28%). Em relação à instituição de ensino, grande parte (68,1%) foi proveniente de universidades públicas. O tipo de estudo mais frequente foi pesquisa laboratorial básica (57,1%). Discussão: os achados do estudo indicam que o número de pesquisas sobre as DOPMs apresentadas nas Reuniões da SBPqO ainda é reduzido, concentrados na região sudeste e nas universidades públicas. Conclusão: realizar novas pesquisas a respeito desse tema é muito importante, pois permite a descoberta de informações relevantes para a saúde dos indivíduos frente a essa neoplasia

Report of rare case of dermatofibrosarcoma protuberans in the buccal mucosa: review of diagnostic, histopathological and immunohistochemical criteria

Dermatofibrosarcoma protuberans (DFSP) is an uncommon intermediate-grade soft tissue sarcoma. The tumor is found preferentially on the trunk, whereas the head and neck region are affected in only 10% to 15% of cases. We report the case of a 44-year-old woman with a 5-month history of an asymptomatic, firm, yellow nodule in the mucosa of the right cheek measuring 2.5 cm. The clinical diagnosis was lipoma and an excisional biopsy was obtained. Histopathological analysis revealed a proliferation of spindle-shaped mesenchymal cells arranged in interlacing fascicles amidst fibrous stroma. Low mitotic activity (2 mitoses per field) and deep cell infiltration into adipose tissue were observed. These features led to the histopathological diagnosis of a malignant low-grade mesenchymal cell tumor. Immunohistochemical analysis revealed negative staining for α-SMA, S-100, and Bcl-2, but positive staining for Ki-67 (18%) and strong and diffuse staining for CD34. These findings were compatible with the diagnosis of DFSP. Only two cases of DFSP in the oral cavity, both involving the cheek mucosa, have been described so far, highlighting the rarity of the present case

Report of rare case of dermatofibrosarcoma protuberans in the buccal mucosa: review of diagnostic, histopathological and immunohistochemical criteria

Dermatofibrosarcoma protuberans (DFSP) is an uncommon intermediate-grade soft tissue sarcoma. The tumor is found preferentially on the trunk, whereas the head and neck region are affected in only 10% to 15% of cases. We report the case of a 44-year-old woman with a 5-month history of an asymptomatic, firm, yellow nodule in the mucosa of the right cheek measuring 2.5 cm. The clinical diagnosis was lipoma and an excisional biopsy was obtained. Histopathological analysis revealed a proliferation of spindle-shaped mesenchymal cells arranged in interlacing fascicles amidst fibrous stroma. Low mitotic activity (2 mitoses per field) and deep cell infiltration into adipose tissue were observed. These features led to the histopathological diagnosis of a malignant low-grade mesenchymal cell tumor. Immunohistochemical analysis revealed negative staining for α-SMA, S-100, and Bcl-2, but positive staining for Ki-67 (18%) and strong and diffuse staining for CD34. These findings were compatible with the diagnosis of DFSP. Only two cases of DFSP in the oral cavity, both involving the cheek mucosa, have been described so far, highlighting the rarity of the present case

Análise da prevalência de erros radiográficos realizados em um serviço de ensino superior do Nordeste do Brasil

Objetivo: Determinar a prevalência de erros em radiografias periapicais cometidos pelos acadêmicos de diferentes períodos do curso de Odontologia da Universidade Federal do Rio Grande do Norte, durante o período de um ano. Material e métodos: As radiografias periapicais foram avaliadas por dois examinadores que identificaram e quantificaram os erros observados de acordo com o tipo (técnica, processamento armazenamento). Para análise estatística, foram utilizados os testes de Kruskal Wallis, Mann-Whitney, Qui-quadrado de Pearson e Exato de Fisher. Resultados: Foram analisadas 522 radiografias periapicais, das quais 236 (45,2%) não apresentaram erros de processamento, técnica e/ou armazenamento e 286 (54,8%) apresentaram pelo menos um erro. Os erros de armazenamento foram os mais frequentes (24,52%), seguidos dos de processamento (23,9%) e técnica (13,40%). Dos erros de armazenamento, a presença de ranhuras nas películas radiográficas foi o erro mais comum (11,9%). Não foi encontrada associação significativa entre a frequência de erros nas radiografias periapicais e os respectivos períodos. Conclusão: Os erros não diminuíram com o aumento da experiência do operador e a maior parte deles poderia ser evitada se o operador fosse mais atento ao procedimento realizado e houvesse condições ideais de armazenamento da película radiográfica.

Clinicopathological study of oral focal mucinosis : a retrospective case series

Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology that exhibits tumor-like growth. It is considered the oral counterpart of cutaneous focal mucinosis or cutaneous myxoid cyst. This is a retrospective study of oral OFM diagnosed over a period of 42 years at an oral pathology service. Clinical, histopathological and immunohistochemical data were analyzed. Alcian blue staining and S-100 immunohistochemistry were performed. Eleven cases were retrieved (4:1 female-to-male ratio). The mean age was 44 years. The gingiva was the most affected site. The main clinical presentation was sessile or pedunculated lesions of fibrous or hyperplasic appearance, most of them asymptomatic. Positive Alcian blue staining and absence of S-100 protein were observed in all specimens, which supported the histological diagnosis of OFM. Surgical excision was the treatment of choice. Although rare, this study supports the inclusion of OFM in the differential diagnosis of intraoral myxoid lesions