Pengembangan Multimedia E-Book 3D Berbasis Mobile Learning untuk Mata Pelajaran Geografi SMA Guna Mendukung Pembelajaran Jarak Jauh

Multimedia E-Book 3D berbasis Mobile Learningdi kembangkan karena dapat membantu penyampaian materi lebih mudah, lebih menarik untuk belajar secara mandiri, serta tidak terbatas dalam ruang dan waktu. Tujuan penelitian ini adalah memberi informasi dan referensi bagi guru. Model Pengembangan yang digunakan yaitu model ADDIE. Pengujian tingkat kesesuaian antara konten aplikasi dengan ekspektasi pengguna dilakukan melalui uji coba ahli media, materi, dan kelompok pengguna. Hasil akhir penelitian ini adalah aplikasi multimedia E-book 3D yang dapat di aplikasikan di dekstop dan smartphone (Mobile Learning). Teknik pengumpulan data dilakukan dengan observasi, wawancara, dan angket. Instrumen penelitian berupa panduan observasi dan wawancara untuk analisis kebutuhan, sedangkan untuk uji produk digunakan kuesioner. Berdasarkan hasil pengembangan produk ini diperoleh hasil uji kelayakan ahli media, ahli materi, dan siswa. Hasil uji coba menunjukkan hasil yang baik, yaitu  kategori layak sampai sangat layak dengan rincian: (1) uji ahli materi mendapat modus skor 4 dengan persentase 60% sangat layak untuk aspek pembelajaran dan modus skor 4 sangat layak dengan persentase 75%, (2) uji ahli media mendapatkan hasil dari modus skor 4 sangat layak dengan persentase 64,71%, (3) uji oleh siswa memperoleh hasil kategori layak dengan modus 3 dan persentase 58,49% untuk kelayakan media. Berdasarkan hasil uji kelayakan maka produk multimedia layak untuk digunakan sebagai media pembelajaran mata pelajaran geografi di SMA

Presentation and outcome of Middle East respiratory syndrome in Saudi intensive care unit patients.

BACKGROUND: Middle East respiratory syndrome coronavirus infection is associated with high mortality rates but limited clinical data have been reported. We describe the clinical features and outcomes of patients admitted to an intensive care unit (ICU) with Middle East respiratory syndrome coronavirus (MERS-CoV) infection. METHODS: Retrospective analysis of data from all adult (>18 years old) patients admitted to our 20-bed mixed ICU with Middle East respiratory syndrome coronavirus infection between October 1, 2012 and May 31, 2014. Diagnosis was confirmed in all patients using real-time reverse transcription polymerase chain reaction on respiratory samples. RESULTS: During the observation period, 31 patients were admitted with MERS-CoV infection (mean age 59 ± 20 years, 22 [71 %] males). Cough and tachypnea were reported in all patients; 22 (77.4 %) patients had bilateral pulmonary infiltrates. Invasive mechanical ventilation was applied in 27 (87.1 %) and vasopressor therapy in 25 (80.6 %) patients during the intensive care unit stay. Twenty-three (74.2 %) patients died in the ICU. Nonsurvivors were older, had greater APACHE II and SOFA scores on admission, and were more likely to have received invasive mechanical ventilation and vasopressor therapy. After adjustment for the severity of illness and the degree of organ dysfunction, the need for vasopressors was an independent risk factor for death in the ICU (odds ratio = 18.33, 95 % confidence interval: 1.11-302.1, P = 0.04). CONCLUSIONS: MERS-CoV infection requiring admission to the ICU is associated with high morbidity and mortality. The need for vasopressor therapy is the main risk factor for death in these patients

Advice on assistance and protection from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons : Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents

The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice in relation to the Chemical Weapons Convention on assistance and protection. We present the SAB’s response to a request from the OPCW Director-General in 2014 for information on the best practices for preventing and treating the health effects from acute, prolonged, and repeated organophosphorus nerve agent (NA) exposure. The report summarises pre- and post-exposure treatments, and developments in decontaminants and adsorbing materials, that at the time of the advice, were available for NAs. The updated information provided could assist medics and emergency responders unfamiliar with treatment and decontamination options related to exposure to NAs. The SAB recommended that developments in research on medical countermeasures and decontaminants for NAs should be monitored by the OPCW, and used in assistance and protection training courses and workshops organised through its capacity building programmes.Peer reviewe

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020