On the Outage Probability of the Full-Duplex Interference-Limited Relay Channel

In this paper, we study the performance, in terms of the asymptotic error probability, of a user which communicates with a destination with the aid of a full-duplex in-band relay. We consider that the network is interference-limited, and interfering users are distributed as a Poisson point process. In this case, the asymptotic error probability is upper bounded by the outage probability (OP). We investigate the outage behavior for well-known cooperative schemes, namely, decode-and-forward (DF) and compress-and-forward (CF) considering fading and path loss. For DF we determine the exact OP and develop upper bounds which are tight in typical operating conditions. Also, we find the correlation coefficient between source and relay signals which minimizes the OP when the density of interferers is small. For CF, the achievable rates are determined by the spatial correlation of the interferences, and a straightforward analysis isn't possible. To handle this issue, we show the rate with correlated noises is at most one bit worse than with uncorrelated noises, and thus find an upper bound on the performance of CF. These results are useful to evaluate the performance and to optimize relaying schemes in the context of full-duplex wireless networks.Comment: 30 pages, 4 figures. Final version. To appear in IEEE JSAC Special Issue on Full-duplex Wireless Communications and Networks, 201

New high-performance liquid chromatography-dad method for analytical determination of arbutin and hydroquinone in rat plasma

Natural substances present in herbal preparations should be carefully used because they can give toxic or therapeutic effects despite of their amount or the way of administration. The safety of products of vegetable origin must be assessed before commercialisation by monitoring the active ingredients and their metabolites. This study was therefore designed to identify and quantify arbutin and its metabolite hydroquinone, naturally present in Arctostaphylos uva-ursi (L.) Spreng plant in rat plasma, after an acute and subacute administration of aqueous arbutin solution in Wistar rats. For this purpose a reversed-phase high-performance liquid chromatography coupled with photodiode array detection was developed to assess the pharmacokinetic of arbutin and hydroquinone in plasma of female rats treated with aqueous arbutin solutions. The detection (arbutin: 0.0617 µg/ml and hydroquinone 0.0120 µg/ml) and quantification (arbutin: 0.2060 µg/ml and hydroquinone: 0.0400 µg/ml) limits were determined. At the arbutin concentration level of 10.7 µg/ml repeatability was 13.33% and its recovery 93.4±6.93%, while at the hydroquinone concentration level of 10.6 µg/ml repeatability was 11.66% and its recovery 92.9±7.75%. Furthermore the method was fully validated and the obtained data indicate that the new method provides good performances

On Fundamental Trade-offs of Device-to-Device Communications in Large Wireless Networks

This paper studies the gains, in terms of served requests, attainable through out-of-band device-to-device (D2D) video exchanges in large cellular networks. A stochastic framework, in which users are clustered to exchange videos, is introduced, considering several aspects of this problem: the video-caching policy, user matching for exchanges, aspects regarding scheduling and transmissions. A family of \emph{admissible protocols} is introduced: in each protocol the users are clustered by means of a hard-core point process and, within the clusters, video exchanges take place. Two metrics, quantifying the "local" and "global" fraction of video requests served through D2D are defined, and relevant trade-off regions involving these metrics, as well as quality-of-service constraints, are identified. A simple communication strategy is proposed and analyzed, to obtain inner bounds to the trade-off regions, and draw conclusions on the performance attainable through D2D. To this end, an analysis of the time-varying interference that the nodes experience, and tight approximations of its Laplace transform are derived.Comment: 33 pages, 9 figures. Updated version, to appear in IEEE Transactions on Wireless Communication

Entropy and Multi-Fractality for the Myeloma Multiple TET 2 gene

The nucleotide and amino-acid distributions are studied for two variants of mRNA of gene that codes for a protein which is involved in multiple myeloid. Some patches and symmetries are singled out, thus, showing some distinctions between the two variants. Fractal dimensions and entropy are discussed as well

Thermal Infrared Observations of Asteroid (99942) Apophis with Herschel

The near-Earth asteroid (99942) Apophis is a potentially hazardous asteroid. We obtained far-infrared observations of this asteroid with the Herschel Space Observatory's PACS instrument at 70, 100, and 160 micron. These were taken at two epochs in January and March 2013 during a close Earth encounter. These first thermal measurements of Apophis were taken at similar phase angles before and after opposition. We performed a detailed thermophysical model analysis by using the spin and shape model recently derived from applying a 2-period Fourier series method to a large sample of well-calibrated photometric observations. We find that the tumbling asteroid Apophis has an elongated shape with a mean diameter of 375$^{+14}_{-10}$ m (of an equal volume sphere) and a geometric V-band albedo of 0.30$^{+0.05}_{-0.06}$. We find a thermal inertia in the range 250-800 Jm$^{-2}$s$^{-0.5}$K$^{-1}$ (best solution at 600 Jm$^{-2}$s$^{-0.5}$K$^{-1}$), which can be explained by a mixture of low conductivity fine regolith with larger rocks and boulders of high thermal inertia on the surface. The thermal inertia, and other similarities with (25143) Itokawa indicate that Apophis might also have a rubble-pile structure. If we combine the new size value with the assumption of an Itokawa-like density and porosity we estimate a mass between 4.4 and 6.2 10$^{10}$ kg which is more than 2-3 times larger than previous estimates. We expect that the newly derived properties will influence impact scenario studies and influence the long-term orbit predictions of Apophis.Comment: Accepted for publication in Astronomy & Astrophysics, 21 pages, 8 figures, 2 table

A ring galaxy at z=1 lensed by the cluster Abell 370

We present a study of a very peculiar object found in the field of the cluster-lens Abell 370. This object displays, in HST imaging, a spectacular morphology comparable to nearby ring-galaxies. From spectroscopic observations at the CFHT, we measured a redshift of $z=1.062$ based on the identification of [O ii] 3727 \AA and [Ne v] 3426 \AA emission lines. These emission lines are typical of starburst galaxies hosting a central active nucleus and are in good agreement with the assumption that this object is a ring-galaxy. This object is also detected with ISO in the LW2 and LW3 filters, and the mid Infra-Red (MIR) flux ratio favors a Seyfert 1 type. The shape of the ring is gravitationally distorted by the cluster-lens, and most particularly by a nearby cluster elliptical galaxy. Using the cluster mass model, we can compute its intrinsic shape. Requiring that the outer ring follows an ellipse we put constraints on the M/L ratio of the nearby galaxy and derive a magnification factor of 2.5 $\pm$ 0.2. The absolute luminosities of the source are then $L_B = 1.3 \ 10^{12} L_{B \odot}$and$\nu$L$_\nu \simeq 4. 10^{10}$L$_\odot$ in the mid-IR.Comment: 5 pages, 5 figures, uses aa.cls, accepted to A&A Letters. Minor changes, Figure 1 revisited and typos adde

STAT3, a hub protein of cellular signaling pathways, is triggered by β-hexaclorocyclohexane

Background: Organochlorine pesticides (OCPs) are widely distributed in the environment and their toxicity is mostly associated with the molecular mechanisms of endocrine disruption. Among OCPs, particular attention was focused on the effects of β-hexaclorocyclohexane (β-HCH), a widely common pollutant. A detailed epidemiological study carried out on exposed population in the “Valle del Sacco” found correlations between the incidence of a wide range of diseases and the occurrence of β-HCH contamination. Taking into account the pleiotropic role of the protein signal transducer and activator of transcription 3 (STAT3), its function as a hub protein in cellular signaling pathways triggered by β-HCH was investigated in different cell lines corresponding to tissues that are especially vulnerable to damage by environmental pollutants. Materials and Methods: Human prostate cancer (LNCaP), human breast cancer (MCF-7 and MDA-MB 468), and human hepatoma (HepG2) cell lines were treated with 10 µM β-HCH in the presence or absence of specific inhibitors for different receptors. All samples were subjected to analysis by immunoblotting and RT-qPCR. Results and Conclusions: The preliminary results allow us to hypothesize the involvement of STAT3, through both its canonical and non-canonical pathways, in response to β-HCH. Moreover, we ascertained the role of STAT3 as a master regulator of energy metabolism via the altered expression and localization of HIF-1α and PKM2, respectively, resulting in a Warburg-like effect

Comparing Methods for the Analysis of δ 13C in Falanghina Grape Must from Different Pedoclimatic Conditions

Agroforestry applications in viticulture are considered a promising strategy to improve vine water status by mitigating the threats of increasing drought due to climate change. The analysis of δ13 C is often used in viticulture to understand vine water use. In this study, the analysis of δ13 C was performed on the must of Falanghina grapevines growing in different pedoclimatic conditions. The aim was to compare the results obtained by the application of two different methodologies, using the whole must or extracted sugars as the matrix. The results showed that the δ13 C values obtained by applying the two methodologies were comparable in all analyzed vineyards independently from the pedoclimatic conditions. Indeed, the proposed method of extraction of the δ13 C on the must as a whole can be both cost-and time-saving for the analysis. This is valuable, considering that the δ13 C of must is becoming more and more used as indicator of vines’ water use. Therefore, the possibility to utilize a simplified method of extraction would enhance the application of the δ13 C at a larger scale to evaluate vine adaptation in the context of climate-change-driven increases in drought