57 research outputs found

    Aquatic invertebrate fauna of western Tasmania

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    Although there are close associations with the south-western fauna , there are nevertheless some aquatic invertebrates found predominantly in western Tasmania, and some biological problems best studied by reference to such animals; examples from two families of crustacea and two insect orders are discussed in this paper . Western Tasmania may be regarded as the freshwater crayfish ( Parastacidae) centre of the State , all four Tasmanian genera being found there . Each genus is discussed in turn ; the habitats utilised are considered and adaptation to these habitats is illustrated by particular reference to burrow systems , calcium distribution in the exoskeleton and where possible , breeding patterns . Data is also provided on distribut i on and associated zoogeographical questions are briefly considered . Two genera of the fami ly Koonungidae ( Syncarida) are found in the west - Micraspides and Koonunga . Their habitats �nd distribution are discus s ed and att ent ion is drawn to the need for more ecological data in order to formulate answers to the zoogeographical issues invo lved . The Odonata exemplify an insect order with g enerally good dispersal power s . Al l dragonfly species found in west ern Tasmania, t ogether with their nymphal habitats, are co llated and discussed. The mo st interest ing speci es are the co ld- c l imat e adapted species , especial ly archai cs such as Archipetalia auriculata and Synthemiopsis gomphomacromioides. At t ention is drawn to the probable importance of diapaus e as an adaptat ion to cold montane habitat s . Three component s are recogni sed in the odonatan fauna , - cosmopo l i tan groups , anci ent Aus tralasian groups , and very anc i ent Gondwanal and re lict s . The Plecoptera is an order demonstrat ing poor vagi l i ty and only 6 of 31 Tasmani an species are shared with mainl and Aus tral i a . The maj ori ty of Tasmanian speci es are cold c l imat e adapted forms and cons equent ly west ern wat ers have a part i cularly conspi cuous s tone fly fauna . Data on the habitats and di stribut ion of a l l speci es found in west ern Tasmania is co l l at ed and discussed. The influence of man on aquat ic environments in west ern Tasmania is bri efly cons idered . Environmental modi fication result s from mining act ivities , hydro -el ectri c deve l opmen t , fore s try practices and from the introduction of exotic speci es such a

    A LOFAR observation of ionospheric scintillation from two simultaneous travelling ionospheric disturbances

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    This paper presents the results from one of the first observations of ionospheric scintillation taken using the Low-Frequency Array (LOFAR). The observation was of the strong natural radio source Cassiopeia A, taken overnight on 18–19 August 2013, and exhibited moderately strong scattering effects in dynamic spectra of intensity received across an observing bandwidth of 10–80 MHz. Delay-Doppler spectra (the 2-D FFT of the dynamic spectrum) from the first hour of observation showed two discrete parabolic arcs, one with a steep curvature and the other shallow, which can be used to provide estimates of the distance to, and velocity of, the scattering plasma. A cross-correlation analysis of data received by the dense array of stations in the LOFAR “core” reveals two different velocities in the scintillation pattern: a primary velocity of ~20–40 ms−1 with a north-west to south-east direction, associated with the steep parabolic arc and a scattering altitude in the F-region or higher, and a secondary velocity of ~110 ms−1 with a north-east to south-west direction, associated with the shallow arc and a scattering altitude in the D-region. Geomagnetic activity was low in the mid-latitudes at the time, but a weak sub-storm at high latitudes reached its peak at the start of the observation. An analysis of Global Navigation Satellite Systems (GNSS) and ionosonde data from the time reveals a larger-scale travelling ionospheric disturbance (TID), possibly the result of the high-latitude activity, travelling in the north-west to south-east direction, and, simultaneously, a smaller-scale TID travelling in a north-east to south-west direction, which could be associated with atmospheric gravity wave activity. The LOFAR observation shows scattering from both TIDs, at different altitudes and propagating in different directions. To the best of our knowledge this is the first time that such a phenomenon has been reported

    Calpain 3 is important for muscle regeneration: Evidence from patients with limb girdle muscular dystrophies

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    <p>Abstract</p> <p>Background</p> <p>Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this study was to investigate how mutations in the four functional domains of calpain 3 affect muscle regeneration.</p> <p>Methods</p> <p>We studied muscle regeneration in 22 patients with LGMD2A with calpain 3 deficiency, in five patients with LGMD2I, with a secondary reduction in calpain 3, and in five patients with Becker muscular dystrophy (BMD) with normal calpain 3 levels. Regeneration was assessed by using the developmental markers neonatal myosin heavy chain (nMHC), vimentin, MyoD and myogenin and counting internally nucleated fibers.</p> <p>Results</p> <p>We found that the recent regeneration as determined by the number of nMHC/vimentin-positive fibers was greatly diminished in severely affected LGMD2A patients compared to similarly affected patients with LGMD2I and BMD. Whorled fibers, a sign of aberrant regeneration, was highly elevated in patients with a complete lack of calpain 3 compared to patients with residual calpain 3. Regeneration is not affected by location of the mutation in the <it>CAPN3 </it>gene.</p> <p>Conclusions</p> <p>Our findings suggest that calpain 3 is needed for the regenerative process probably during sarcomere remodeling as the complete lack of functional calpain 3 leads to the most severe phenotypes.</p

    Factors associated with dysmorphic concern and psychiatric morbidity in plastic surgery outpatients

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    Objectives: To compare new referrals to a plastic surgery clinic for cosmetic (non-medically explained) reasons with a control group of equal size with medically explained symptoms. Method: Patients attending for cosmetic (non-medically explained) reasons were compared with the controls using the general health questionnaire (GHQ), and dysmorphic concern questionnaire (DCQ). Patients were divided into high and low DCQ scores on the basis of their median scores. Results: Ninety subjects were approached of whom 84 (93%) participated giving 42 patients each in the cosmetic (non-medically explained) and control groups. Forty-four per cent were referred for mammoplasty (n = 37) and 8% for rhinoplasty (n = 7). The other 40 cases (48%) were for other procedures including excision, abdominoplasty and blepharoplasty. Thirty-two per cent of the sample were GHQ cases (n = 27). Patients presenting for cosmetic (non-medically explained) reasons were 13 times more likely to be female (95% CI = 4.3–41), nine times more likely to have high DCQ scores (95% CI = 3.3–24), six times more likely to be GHQ cases (95% CI = 2.1–17), and seven times more likely to present for mammoplasty. The same factors were associated with high DCQ scores. Patients with high DCQ scores were 32 times as likely to be GHQ cases (95% CI = 6.8–151). On multivariate analysis, dysmorphic concern emerged as the only independent predictor of GHQ caseness rather than sex, surgical diagnosis or procedure (adjusted OR = 32.0, 95 % CI = 6.5–156). Similarly, only GHQ caseness and presentation for cosmetic (non-medically explained) surgery independently predicted DCQ score. Conclusions: Patients presenting for cosmetic (non-medically explained) surgery have high rates of dysmorphic concern and psychiatric morbidit
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