836 research outputs found

    Uncertain Territory: Family Reunification and the Plight of Unaccompanied Minors in Canada

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    In recent years, Canada has experienced a significant increase in the number of refugee claims from unaccompanied minors: those children who are separated from both parents and are not being cared for by an adult who, by law or custom, has the responsibility to do so. Following a brief examination of the nature and scope of the unaccompanied minor problem, the paper explores the difficulties the Immigration and Refugee Protection Act sponsorship schemes present to these children as they endeavor to reunite with their families. The author argues that the Act provides limited opportunities for these children to pursue family reunification, which both undermines Canada’s international legal obligations pursuant to the UN Convention on the Rights of the Child, and conflicts with the objectives advocated by domestic immigration and refugee legislation. Having exposed several of the unique challenges these children create for current immigration law, the author concludes by proposing several legal and policy reforms that could assist in addressing the special circumstances and particular needs of unaccompanied minors who seek family reunification in Canada

    Person centred phenomenology : service user experiences of exercise

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    Purpose: The study aimed to explore the lived experience of sport and exercise amongst a group of mental health service users. Participants were recruited from a north of England NHS mental health trust that was piloting a sport and exercise intervention for adults with mental health needs. Design/methodology/approach: In depth semi-structured interviews were conducted with five mental health service users. The chosen phenomenological methodology was collaborative and interpretive. Findings: Two essential themes were highlighted; ‘Intermittent health breaking through heavy clouds of illness’ and ‘The cycle of recovery’. In addition, this person centred research identified a number of intervention benefits beyond those relating to the impact of physical activity on mental health and wellbeing. The main findings are expressed using visual imagery which participants found expressed their perceptions and experiences better than written prose. This includes the way day to day illness impacts on the journey of health for people with mental health problems. Research limitations/implications: The intervention looked to help the transition between leaving mental health services and developing a regular routine to promote recovery. The study illuminates the voices of service users and identifies that sport and exercise for mental health service users can be beneficial for recovery and feelings of belonging which can strengthen perceptions of the self. Practical implications: Social implications: Originality/value: Few studies have approached this methodological approach. This study demonstrates the value of phenomenological research with a collaborative, person centred or indeed an involved patient focus. This collaborative approach enabled a shared understanding of the phenomena

    Changes in Canadian Identity Attitudes Over a Twenty Year Period: 1981-2001

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    This project examines attitude change between 1981 and 2001 for a population of young, well educated Canadians, employing evaluation, potency and activity (EPA) semantic differential ratings of approximately 800 social identities. This comprises my larger data set. I also employ a smaller subset of 102 social identities drawn from the larger data set to explore changes across three points in time (1981, 1995, and 2001) for 102 social identities, supplementing my analysis across two points in time (1981 and 2001) for 800 social identities. The objectives for this dissertation are: (1) to assess stability of attitudes for social identities over time; (2) to identify and describe patterns of change in identity attitudes and to connect observed changes in identity attitudes to historical events, and to social and cultural change in Canadian society; (3) to explore the extent to which identities that cluster together in EPA space define social institutions; and (4) to explore how changes in identity attitudes affect role expectations over time. Despite significant shifts in attitudes for a number of identities, approximately 80% of identity attitudes remained stable over time, confirming findings from past research that cultural sentiments are slow to change. Observed changes could be connected to social and cultural structure. Specifically, dramatic changes occurred for religious and sexual preference/orientation identities. Numerous religious identities decreased on evaluation for male respondents between 1981 and 1995 and then were restored to earlier levels by 2001. Female respondents were not as forgiving and 1995 decreases in evaluation were sustained. These changes are connected to increased secularization and earlier sexual scandals in religious institutions. Sexual preference/orientation identities increased significantly on evaluation for both males and females. However, increases for females were more dramatic and occurred across all three points in time while changes in attitudes for males occurred between 1981 and 1995 and then changed little between 1995 and 2001. These changes can be connected to numerous factors, including the increased visibility of gay/lesbian culture in mainstream media and the absence of a strong anti-gay counter movement. Although social identities clustered in interesting ways, cluster analysis was not very successful in defining social institutions. Computer simulations revealed how role and behaviour expectations change with changes in identity attitudes. For example, there is obvious increase in evaluation between 1981 and 2001 for the behavior of a police officer toward a homosexual. This dissertation concludes by addressing methodological issues such as sample size and generalizability. It is suggested that the corpus of identities should be continually updated to include identities that are emerging from pop culture. Finally, four areas of future research are suggested: (1) a continual monitoring of cultural sentiments; (2) a more detailed focus on individual social institutions; (3) a confirmation of computer predictions with qualitative interview data; and (4) identifying the implications of this research for trend analysis. Practical implications of this dissertation research include the use of computer simulations of identity-role processes in the areas of education and policy research

    Using the Dynamic Microsimulation MINOS to Evidence the Effect of Energy Crisis Income Support Policy (Short Paper)

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    Rates of anxiety and depression are increasing due to financial stress caused by energy pricing with over half of UK homes unable to afford comfortable heating. UK Government policies to address this energy crisis have been implemented with limited evidence and substantial criticism. This paper applies the dynamic microsimulation MINOS, which utilises longitudinal Understanding Society data, to evidence change in mental well-being under the Energy Price Cap Guarantee and Energy Bill Support Scheme Policies. Results demonstrate an overall improvement in Short Form 12 Mental Component Score (SF12-MCS) both on aggregate and over data zone spatial areas for the Glasgow City region compared with a baseline of no policy intervention. This is work in progress and discussion highlights potential future work in other energy policy areas, such as Net Zero

    The Effect of Root Exudate 7,4\u27-Dihydroxyflavone and Naringenin on Soil Bacterial Community Structure

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    Our goal was to investigate how root exudate flavonoids influence the soil bacterial community structure and to identify members of the community that change their relative abundance in response to flavonoid exudation. Using a model system that approximates flavonoid exudation of Medicago sativa roots, we treated a soil with 7,4′-dihydroxyflavone and naringenin in two separate experiments using three different rates: medium (equivalent to the exudation rate of 7,4′-dihydroxyflavone from M. sativa seedlings), high (10× the medium rate), and low (0.1× the medium rate). Controls received no flavonoid. Soil samples were subjected to ATP assays and 16S rRNA gene amplicon sequencing. The flavonoid treatments caused no significant change in the soil ATP content. With the high 7,4′-dihydroxyflavone treatment rate, operational taxonomic units (OTUs) classified as Acidobacteria subdivision 4 increased in relative abundance compared with the control samples, whereas OTUs classified as Gaiellales, Nocardioidaceae, and Thermomonosporaceae were more prevalent in the control. The naringenin treatments did not cause significant changes in the soil bacterial community structure. Our results suggest that the root exudate flavonoid 7,4′-dihydroxyflavone can interact with a diverse range of soil bacteria and may have other functions in the rhizosphere in addition to nod gene induction in legume—rhizobia symbiosis

    Participants' use of enacted scenes in research interviews: a method for reflexive analysis in health and social care

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    In our study of a workforce intervention within a health and social care context we found that participants who took part in longitudinal research interviews were commonly enacting scenes from their work during one-to-one interviews. Scenes were defined as portions of the interviews in which participants directly quoted the speech of at least two actors. Our analysis in this paper focuses on these enacted scenes, and compares the content of them before and after the intervention. We found that, whilst the tensions between consistency and change, and change management, were common topics for scene enactment in both pre and post-intervention data, following the intervention participants were much more likely to present themselves as active agents in that change. Post-intervention enacted scenes also showed participants' reports of taking a service user perspective, and a focus on their interactions with service users that had been absent from pre-intervention data. In addition, descriptions of positive feeling and emotions were present in the post-intervention enacted scenes. We suggest that this analysis confirms the importance of enacted scenes as an analytic resource, and that this importance goes beyond their utility in identifying the impact of this specific intervention. Given the congruence between the themes prominent in enacted scenes, and those which emerged from a more extensive qualitative analysis of these data, we argue that enacted scenes may also be of wider methodological importance. The possibility of using scene enactment as an approach to the validation of inductive analysis in health and social care settings could provide a useful methodological resource in settings where longitudinal ethnographic observation of frontline care staff is impossible or impractical

    Inhibition of NF-κB-mediated signaling by the cyclin-dependent kinase inhibitor CR8 overcomes pro-survival stimuli to induce apoptosis in chronic lymphocytic leukemia cells

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    Purpose: Chronic lymphocytic leukemia (CLL) is currently incurable with standard chemotherapeutic agents, highlighting the need for novel therapies. Overcoming proliferative and cytoprotective signals generated within the microenvironment of lymphoid organs is essential for limiting CLL progression and ultimately developing a cure. Experimental Design: We assessed the potency of cyclin-dependent kinase (CDK) inhibitor CR8, a roscovitine analog, to induce apoptosis in primary CLL from distinct prognostic subsets using flow cytometry–based assays. CLL cells were cultured in in vitro prosurvival and proproliferative conditions to mimic microenvironmental signals in the lymphoid organs, to elucidate the mechanism of action of CR8 in quiescent and proliferating CLL cells using flow cytometry, Western blotting, and quantitative real-time PCR. Results: CR8 was 100-fold more potent at inducing apoptosis in primary CLL cells than roscovitine, both in isolated culture and stromal-coculture conditions. Importantly, CR8 induced apoptosis in CD40-ligated CLL cells and preferentially targeted actively proliferating cells within these cultures. CR8 treatment induced downregulation of the antiapoptotic proteins Mcl-1 and XIAP, through inhibition of RNA polymerase II, and inhibition of NF-κB signaling at the transcriptional level and through inhibition of the inhibitor of IκB kinase (IKK) complex, resulting in stabilization of IκBα expression. Conclusions: CR8 is a potent CDK inhibitor that subverts pivotal prosurvival and proproliferative signals present in the tumor microenvironment of CLL patient lymphoid organs. Our data support the clinical development of selective CDK inhibitors as novel therapies for CLL

    Peer-to-peer support on Facebook for caregivers of children and youth with complex care needs in New Brunswick: An environmental scan

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    This environmental scan aimed to describe the purpose, use, and reach of health-related peer-to-peer support groups on Facebook for caregivers of children and youth with complex care needs in New Brunswick. A total of 3,104 searches on Facebook and consultations with thirty-two stakeholders led to the identification of forty-seven Facebook support groups (twenty-one active). Groups targeted a range of conditions, with autism and related intellectual disabilities appearing most frequently. Content analysis of posts indicated that groups were primarily used to exchange informational support. This study showed that Facebook-based peer-to-peer support groups are available to families of children and youth with complex care needs in the province. This work also lays a foundation for future scans of Facebook-based support groups in other Canadian provinces and beyond.La présente analyse du milieu visait à décrire l’objectif, l’utilisation et la portée des groupes de soutien entre pairs liés à la santé sur Facebook pour les personnes qui s’occupent d’enfants et de jeunes ayant des besoins de soins complexes au Nouveau-Brunswick. En tout, 3 104 recherches sur Facebook et des consultations auprès de 32 intervenants ont permis de repérer 47 groupes de soutien sur Facebook, dont 21 groupes actifs. Des groupes ciblaient un éventail de troubles; l’autisme et les déficiences intellectuelles connexes étaient ceux qui étaient les plus fréquents. Les analyses de contenu des messages ont révélé que les groupes étaient principalement utilisés pour échanger des informations de soutien. Selon cette étude, des groupes de soutien entre pairs sur Facebook sont offerts aux familles d’enfants et de jeunes ayant des besoins de soins complexes dans la province. De plus, ce travail jette les bases de futures analyses de groupes de soutien sur Facebook d’autres provinces canadiennes et d’ailleurs

    Bearded pig (Sus barbatus) utilisation of a fragmented forest-oil palm landscape in Sabah, Malaysian Borneo

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    Context: Oil palm plantations have become a dominant landscape in Southeast Asia, yet we still understand relatively little about the ways wildlife are adapting to fragmented mosaics of forest and oil palm. The bearded pig is of great ecological, social, and conservation importance in Borneo and is declining rapidly due to habitat loss and overhunting. Aims: We sought to assess how the bearded pig is adapting to oil palm expansion by investigating habitat utilisation, activity patterns, body condition, and minimum group size in a mosaic composed of forest fragments and surrounding oil palm. Methods: We conducted our study in Sabah, Malaysian Borneo, in and around the Lower Kinabatangan Wildlife Sanctuary, an area consisting of secondary forest fragments (ranging 1200-7400 ha) situated within an extensive oil palm matrix. We modelled bearded pig habitat use in forest fragments and oil palm plantations using survey data from line transects. Camera traps placed throughout the forest fragments were used to assess pig activity patterns, body condition, and minimum group size. Key results: All forest transects and 80% of plantation transects showed pig presence, but mean pig signs per transect were much more prevalent in forest (70.00 ± 13.00 SE) than in plantations (0.91 ± 0.42 SE). Pig tracks had a positive relationship with leaf cover and a negative relationship with grass cover; pig rooting sites had a positive relationship with wet and moderate soils as compared to drier soils. Pigs displayed very good body condition in forests across the study area, aggregated in small groups (mean = 2.7 ± 0.1 SE individuals), and showed diurnal activity patterns that were accentuated for groups with piglets and juveniles. Conclusions: Our findings suggest that bearded pigs in our study area regularly utilise oil palm as habitat, given their signs in most oil palm sites surveyed. However, secondary forest fragments adjacent to oil palm remain the most important habitat for the bearded pig, as well as many other species, and therefore must be conserved. Implications: Consistent bearded pig presence in oil palm is a potential indication of successful adaptation to agricultural expansion in the study area. However, the net effect of oil palm expansion in the region on bearded pig populations remains unknown

    In situ monitoring of powder blending by non-invasive Raman spectrometry with wide area illumination

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    A 785 nm diode laser and probe with a 6 mm spot size were used to obtain spectra of stationary powders and powders mixing at 50 rpm in a high shear convective blender. Two methods of assessing the effect of particle characteristics on the Raman sampling depth for microcrystalline cellulose (Avicel), aspirin or sodium nitrate were compared: (i) the information depth, based on the diminishing Raman signal of TiO2 in a reference plate as the depth of powder prior to the plate was increased, and (ii) the depth at which a sample became infinitely thick, based on the depth of powder at which the Raman signal of the compound became constant The particle size, shape, density and/or light absorption capability of the compounds were shown to affect the "information" and "infinitely thick" depths of individual compounds. However, when different sized fractions of aspirin were added to Avicel as the main component, the depth values of aspirin were the same and matched that of the Avicel: 1.7 mm for the "information" depth and 3.5 mm for the "infinitely thick" depth. This latter value was considered to be the minimum Raman sampling depth when monitoring the addition of aspirin to Avicel in the blender. Mixing profiles for aspirin were obtained non-invasively through the glass wall of the vessel and could be used to assess how the aspirin blended into the main component, identify the end point of the mixing process (which varied with the particle size of the aspirin), and determine the concentration of aspirin in real time. The Raman procedure was compared to two other non-invasive monitoring techniques, near infrared (NIR) spectrometry and broadband acoustic emission spectrometry. The features of the mixing profiles generated by the three techniques were similar for addition of aspirin to Avicel. Although Raman was less sensitive than NIR spectrometry, Raman allowed compound specific mixing profiles to be generated by studying the mixing behaviour of an aspirin-aspartame-Avicel mixture
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