Acne induced by amineptine

Relata-se um caso grave de lesões acne-símile associada a amineptina (Survector®), proeminentes na face e dorso, acometendo outros sítios não afetados pela acne vulgar, como períneo, braços e pernas. As lesões apareceram após a auto-administração crônica de altas doses do medicamento. Lesões ceratoacantoma-símile também estavam presentes, tendo as lesões menores resposta satisfatória ao tratamento com imiquimod tópico. O relato é significativo pela raridade da doença.UNIFESP Universidade Federal de Minas Gerais da Faculdade de MedicinaUniversidade Federal de Minas Gerais Acadêmica de Medicinade Ciências Médicas de Minas Gerais Casa de Belo Horizonte Clínica DermatológicaUniversidade Federal de Minas Gerais Instituto de Ciências BiológicasUNIFESP, Universidade Federal de Minas Gerais da Faculdade de MedicinaSciEL

Understanding gender differences through free interactions at scholar environment

Evolutionary Psychology considers that gender differences in play are a result of cultural influences upon pre-dispositions selected in the species. The compatibility of these differences with theoretical prevision was investigated. Seventy three six/seven years old students of private schools were recorded in four 30 minutes sessions. Playful behavior frequency and playmate choice were counted. Later, 21 children were asked about favourite plays and how they classified those plays accordingly to gender patterns. Both sexes participated in similar activities but their interactions were mostly restricted to members of the same sex. It was also observed that there were topographic differences in the way they played, accordingly to sex. The interviews, as shown in the literature, allowed to identify that the speech and the behavior observed were different, with a higher cultural influence upon the speech.Para a Psicologia Evolucionista as diferenças de gênero existentes nas brincadeiras resultam de influências culturais que interagem com uma pré-disposição selecionada na espécie. Objetivou-se investigar se tais diferenças seriam compatíveis com dimorfismo sexual descrito na literatura da área. Setenta e três alunos entre seis e sete anos de uma escola particular foram filmados em quatro sessões de 30 minutos de recreio. Contabilizou-se a freqüência dos comportamentos e os pares com que ocorriam. Posteriormente, 21 crianças foram entrevistadas sobre suas brincadeiras prediletas e suas classificações de brincadeiras segundo o gênero. Pôde-se observar que ambos os sexos participam de atividades similares, mas em interações intra-sexuais. Além disso, observaram-se diferenças topográficas na forma de brincar, de acordo com o sexo. Nas entrevistas, como previa a literatura, foram registradas diferenças entre o relatado e o observado, indicando maior influência cultural sobre o conteúdo relatado

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Percepção da violência urbana e autoavaliação de saúde por jovens adultos

Submitted by Éder Freyre ([email protected]) on 2017-03-03T14:04:43Z No. of bitstreams: 1 va_Aline_Bentes_CPqRR_2016.pdf: 451491 bytes, checksum: 8116534b6e38a1b8d8a12c09e1f002f6 (MD5)Approved for entry into archive by Nuzia Santos ([email protected]) on 2017-03-03T14:05:21Z (GMT) No. of bitstreams: 1 va_Aline_Bentes_CPqRR_2016.pdf: 451491 bytes, checksum: 8116534b6e38a1b8d8a12c09e1f002f6 (MD5)Made available in DSpace on 2017-03-03T14:05:21Z (GMT). No. of bitstreams: 1 va_Aline_Bentes_CPqRR_2016.pdf: 451491 bytes, checksum: 8116534b6e38a1b8d8a12c09e1f002f6 (MD5) Previous issue date: 2016Coordenação de Aperfeiçoamento do Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do estado de Minas Gerais (Fapemig)Ministério da Saúde (MS)Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil.Não há definição única e universal do que seja saúde. A autoavaliação de saúde (AAS) é um dos indicadores mais utilizados em estudos epidemiológicos para avaliar a saúde de grupos populacionais. Sexo e idade são determinantes individuais reconhecidos da AAS. É ainda limitado o conhecimento sobre a AAS em jovens adultos (18-29anos), faixa etária pouco estudada quanto a autoavaliação de saúde. O objetivo deste estudo foi determinar e quantificar a associação entre a violência percebida na vizinhança e AAS entre jovens adultos, estratificando por sexo. A variável explicativa de interesse foi a violência urbana percebida. Participaram do estudo 955 jovens adultos (18-29anos) residentes em Belo Horizonte, Minas Gerais, de 2008 a 2009. O escore de violência urbana percebida foi construído considerando variáveis que avaliaram a insegurança do respondente e a sua percepção de medo, perigo de sofrer alguma forma de violência na vizinhança, utilizando-se análise fatorial exploratória. Com relação à autoavaliação da saúde, 81,7% dos jovens adultos considerou como muito boa/boa, 18,3% como razoável/ ruim/muito ruim. No modelo final, após ajustes para as variáveis de confusão, a violência urbana percebida na vizinhança associou-se a pior AAS apenas nas mulheres jovens (OR = 1,50; IC95%: 1,03 – 2,15). Embora não sejam firmemente estabelecidos os mecanismos responsáveis por essa associação, os resultados deste estudo indicam que políticas públicas e de saúde devem considerar intervenções sobre o entorno físico e social do bairro ou vizinhança que promovam maior percepção de segurança no local em que se vive o que impactará positivamente na saúde das pessoas, especialmente das mulheres.There is no single, universal definition of what health. The self-rated health (SRH) is one of the indicators most commonly used in epidemiological studies to assess the health of populations. Gender and age are recognized individual determinants of SRH. It is still limited knowledge about SRH in young adults (18-29anos). The aim of this study was to determine and quantify the association between perceived violence in the neighborhood and SRH among young adults, stratified by sex. The explanatory variable of interest was the perceived urban violence. The study enrolled 955 young adults (18-29anos) living in Belo Horizonte, Minas Gerais, from 2008 to 2009. The urban violence score perceived was estimated considering variables that evaluated the insecurity of the respondent and his perception of fear, danger of suffering some form of violence in the neighborhood, using exploratory factor analysis. Regarding the self-rated health, 81.7% of young adults considered as very good / good, 18.3% as fair / poor / very poor. In the final model, after adjustment for confounding variables, urban violence seen in the neighborhood was associated with worse SRH only in young women (OR = 1,50; IC95%: 1,03 – 2,15). Although not firmly established the mechanisms responsible for this association, the results of this study indicate that public and health policies should consider interventions on the physical and social environment of the neighborhood to promote greater safety awareness on where you live what impact positively on the health of people, especially women

Self-rated health and perceived violence in the neighborhood is heterogeneous between young women and men

Abstract Background Self-rated health (SRH) is the general perception of an individual’s own health and a key indicator to measure health in population-based studies. Few studies have examined the association between perceived urban violence and SRH among young adults. There were an estimated 475,000 deaths in 2012 as a result of homicide on the world. Sixty percent of these deaths occurred among males aged 15–44 years, making homicide the third leading cause of death for this population group. This study aimed to determine and quantify the association between sex-specific perception of violence in the neighborhood and SRH among young adults. Methods Participants included 955 young adults (18–29 years) residing in Belo Horizonte, Minas Gerais, Brazil between 2008 and 2009. Logistic regression analysis was used to estimate the strength of the associations. The perceived urban violence score was constructed from variables that assessed the respondents’ insecurity and perception of fear and danger of suffering some form of violence in the neighborhood using exploratory factor analysis. Results 18,3% of respondents rated their health as fair/ poor/very poor. Among women, fair/ poor/very poor SRH was associated with age between 25 and 29 years, low socioeconomic status score, being dissatisfied with weight, not exercising regularly, not having a healthy diet, and having some chronic disease. Men who rated their health as fair/poor/very poor more frequently smoked, were dissatisfied with their weight, did not exercise regularly, consumed fewer fruits and vegetables, and had some chronic disease compared to men who rated their health as very good/good. In the final model, after adjusting for confounding variables, perceived violence in the neighborhood was associated with poor SRH in young women only (OR = 1.52; 95% CI: 1.04–2.21). Conclusion The results indicate that public and health policies should implement interventions on the neighborhood physical and social environment to improve the perception of safety and have a positive impact on people’s health, especially women

Children with sickle cell disease and severe COVID‐19 presenting single nucleotide polymorphisms in innate immune response genes – A case report

Abstract Here we report three clinical cases of children with sickle cell disease (SCD) and severe COVID‐19 who evolved with complications during hospitalization or after discharge. They present single nucleotide polymorphisms in tlr‐7 and tirap genes, identified from 37 patients under 16 years old hospitalized from September 2020 to May 2021 in the Hospital João Paulo II, Belo Horizonte, Brazil. They presented significant complications of SCD as acute chest syndrome, splenic sequestration, and pain crisis during hospitalization or up to 2 months after SARS‐CoV‐2 infection. They all required transfusion of concentrated red blood cells and hospitalization in a reference hospital to care for children with SCD