Safe local aerial manipulation for the installation of devices on power lines: Aerial-core first year results and designs

Article number 6220The power grid is an essential infrastructure in any country, comprising thousands of kilometers of power lines that require periodic inspection and maintenance, carried out nowadays by human operators in risky conditions. To increase safety and reduce time and cost with respect to conventional solutions involving manned helicopters and heavy vehicles, the AERIAL-CORE project proposes the development of aerial robots capable of performing aerial manipulation operations to assist human operators in power lines inspection and maintenance, allowing the installation of devices, such as bird flight diverters or electrical spacers, and the fast delivery and retrieval of tools. This manuscript describes the goals and functionalities to be developed for safe local aerial manipulation, presenting the preliminary designs and experimental results obtained in the first year of the project.European Union (UE). H2020 871479Ministerio de Ciencia, Innovación y Universidades de España FPI 201

Cambio climático a nivel de nicho y caña de azúcar. I Tamazula, Jalisco, México

Rev. iberoam. bioecon. cambio clim. Vol.1(1) 2015; 185-206El presente trabajo tuvo como objetivo estudiar las variaciones relacionadas con la gran sequía invernal (GSI), la sequía intraestival (SI), la ocurrencia de heladas, golpes de calor y excesos de lluvia, aprovechando datos históricos disponibles de la localidad de Tamazula, Jalisco como un espacio dentro de un nicho; así mismo, comparar las variaciones antes y después de 1975, año tomado como referencia de la manifestación del último cambio climático según la Figura 2. Otro objetivo colateral fue vincular dicho desarrollo histórico con un experimento de variedades de caña realizado en 2011-2013 cerca de Tamazula, Jalisco.Rev. iberoam. bioecon. cambio clim. Vol.1(1) 2015; 185-20

Cambio climático a nivel de nicho y caña de azúcar. I Tamazula, Jalisco, México

El presente trabajo tuvo como objetivo estudiar las variaciones relacionadas con la gran sequía invernal (GSI), la sequía intraestival (SI), la ocurrencia de heladas, golpes de calor y excesos de lluvia, aprovechando datos históricos disponibles de la localidad de Tamazula, Jalisco como un espacio dentro de un nicho; así mismo, comparar las variaciones antes y después de 1975, año tomado como referencia de la manifestación del último cambio climático según la Figura 2. Otro objetivo colateral fue vincular dicho desarrollo histórico con un experimento de variedades de caña realizado en 2011-2013 cerca de Tamazula, Jalisc

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation

The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation has since reappeared in the Delta subvariant AY.4.2, raising questions about its specific effect on viral infection. We report combined serological, functional, structural and computational studies characterizing the impact of this mutation. Our results reveal that S:A222V promotes an increased RBD opening and slightly increases ACE2 binding as compared to the parent S:D614G clade. Finally, S:A222V does not reduce sera neutralization capacity, suggesting it does not affect vaccine effectiveness

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation has now reappeared in the Delta subvariant AY.4.2, raising questions about its specific effect on viral infection. We report combined serological, functional, structural and computational studies characterizing the impact of this mutation. Our results reveal that S:A222V promotes an increased RBD opening and slightly increases ACE2 binding as compared to the parent S:D614G clade. Finally, S:A222V does not reduce sera neutralization capacity, suggesting it does not affect vaccine effectiveness.This research work was supported by the European Commission–NextGenerationEU through the CSIC Global Health Platform. Additionally, authors would like to acknowledge economic support from the Spanish Ministry of Science and Innovation through Grants: PID2019-104757RB-I00 funded by MCIN/AEI/ 10.13039/501100011033, RTI2018-094399-A-I00, and “ERDF A way of making Europe”, by the “European Union”, Grant SEV 2017-0712 funded by MCIN/AEI /10.13039/501100011033, the “Comunidad Autónoma de Madrid" through Grant: S2017/BMD3817, and the European Union (EU) and Horizon 2020 through grants: Marie-Curie Fellowship EnLaCES (MSCA IF 2020, Proposal: 101024130) (to JK), HighResCells (ERC - 2018 - SyG, Proposal: 810057), and iNEXT-Discovery (Proposal: 871037). AM, VR, JB and JLL are funded by CIBERER-ISCIII (proposal: COV20/00437), Fondo Supera COVID-19 (proposal: CSICCOVID19-082), Banco Santander (Proposal: BlockAce), and CSIC PTI Salud Global (Proposal: 202080E110). VR is funded by the Spanish Ministry of Science and Innovation through Grant PID2020-120322RB-C21. IC is funded by project PID2019-104477RB-100, Fondo COVID COV20/00140 and ERC CoG 101001038. MC is funded by the RyC program from the Spanish Ministry of Science and Innovation, the Generalitat Valenciana (SEJI/2019/011).N

The role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

Resumen del trabajo presentado a las II Jornadas Científicas PTI + Salud Global, celebradas los días 5 y 6 de octubre de 2022 en el Auditorio Santiago Grisolía de Valencia (España).Peer reviewe

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac