Losada, Basilio: Poesía Gallega de Hoy - Antología -

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Testamento de Pedro Milachami, un curaca cañari en la región de los Wanka, Perú (1662)

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Las escalas como técnica para la medición del proceso de aculturación o competencia intercultural

En el contexto español hay dos ideas a la luz de los datos, estadísticas e investigaciones que se repiten constantemente, en primer lugar, que los procesos migratorios en España se han convertido en un fenómeno muy importante. Los extranjeros según los datos del padrón municipal, a fecha de 1 de enero de 2003, representan el 6,24% de la población total de España. La población extranjera para ese período era de 2.664.168 personas, lo que supone un aumento del 34,69% respecto de los 1.977.944 personas inscritas en 20023. En segundo lugar, España ha pasado de ser un país de emigración a ser un país de inmigración. Dicho fenómeno tiene importantes implicaciones por un lado, sobre el concepto de ciudadanía, y por otro en la conformación de espacios donde el multiculturalismo o la interculturalidad se viven día a día, también destacar el choque cultural que estos procesos implican en la mayor parte de las ocasiones. En este sentido, algunos de los procesos que componen el concepto de ciudadanía son la aculturación o competencia intercultural y la identidad

Mechanical characterization of a new architectural concrete with glass-recycled aggregate

Concrete is a material which is widely used in architecture, not only for structural purposes but also for architectural elements for its versatility and excellent performance. However, the manufacturing of this material as a mixture of water, cement, and ¿ne and coarse aggregate comes with a high environmental cost, such as gas emissions, among other things. This is the reason why di¿erent alternatives are being proposed in order to replace coarse aggregates with other recycled materials, as it is one of the less sustainable components of the mixture in terms of extraction. One of these alternatives is recycled glass coming from drinking bottles, crushed into small grains and mixed in the same proportions as regular aggregates. This study proposes the mechanical characterization of a new architectural concrete mixture by using white Lafarge cement and glass-recycled aggregates. This proposed concrete is made especially for architectural elements like façade panels, rather than structural elements. The mechanical evaluation of this new material is done through a set of experimental tests under compression and also bending, comparing three di¿erent ratios of glass aggregate in the mixture.Peer ReviewedPostprint (published version

Los requena, una enigmática familia de pintores del renacimiento : A propósito de Gaspar Requena "El Joven"

[email protected] recientes exposiciones que viene realizando la Fundación “La Luz de las Imágenes” en el ámbito de las distintas diócesis valencianas no sólo ha acercado al público numerosas obras de arte en condiciones de ser vistas y admiradas, sino que también ha posibilitado su estudio. En ese contexto presentamos un acercamiento al taller de los Requena; una familia de pintores activa en el Reino de Valencia entre 1531 y 1605 aproximadamente que, en su desigual producción, deja entrever las innegables deudas con Paolo da San Leocadio, los Hernandos y, particularmente, Joan de Joanes.Recent exhibitions produced by the Foundation La Luz de las Imágenes in Valencian dioceses has allowed for numerous works of art to be seen, admired and studied under optimal conditions. In this context we offer an approach to the workshop of the Requena family, painters active in the Kingdom of Valencia between approximately 1531 and 1605. These artists, in their uneven production, owed much to Paolo da San Leocadio, the Hernandos and particularly, Joan de Joanes

Sustainable Companies, Addressing Climate Change. A Theoretical Review

Climate change is an unavoidable threat with potentially irreversible effects. In the current economic context, globalization significantly increases the unbalanced use of finite, non-renewable sources of energy. This study aims to describe the main characteristics of sustainable companies, based on ideals and values that are committed to the development of the planet, consuming fewer resources than those that they create. Sustainable companies are based on fundamental principles such as the environment (renewable energy resources, sustainable development, preservation of the environment, responsible energy use, minimization of emissions, eco-efficiency, and the circular economy) and mobility (collective public transport, electric vehicles, clean non-motorized mobility systems). In light of this situation, a number of improvement actions have been proposed aimed at sustainable business development (smart environmental sensor networks, energy efficiency, integrated water cycle management, efficient lighting, smart metering, smart irrigation, environmental protection, smart waste management, smart public transport, monitoring of tolls and access to restricted areas, traffic management, fleet management, smart parking, and electric vehicles). Following a theoretical review of the main related studies, it is concluded that there are gaps in information and research related to climate change. At the same time, a further conclusion is that the instruments currently used to mitigate its effects are insufficient and inadequate. Greater indexes of governance and transnational strategy are urgently needed. Finally, there is also a need for sustainable companies that combine business development with the environment and the protection of the planet

Enhanced performance of gelatin 5-fluorouracil-containing nanoparticles against squamous cell carcinoma in simulated chronic wounds conditions

Chronic wounds are considered a silent epidemic affecting a significant fraction of the World population. Their treatment supposes a large fraction of the public spending on the health of developed countries. In chronic wounds secondary to burns, trauma, UV light radiation, and diabetes, among others, the development of squamous cell carcinoma (SCC) has been reported. If detected early, 95% of SCC are most comfortable to be treated and cured; however, 5% of advanced SCC is more dangerous and challenging to treat. It has been reported that the pH value within the wound-milieu influences indirectly and directly all biochemical reactions taking place in this process of healing. Differences in pH values between normal skin and chronic cutaneous wounds could be considered in designing and developing stimuli-responsive nanomaterials. In this work, the anticancer drug 5-fluorouracil (5-FU) inclusion on gelatin-based NPs for SCC treatment has been projected. The present work goal is to prepare and characterize physicochemical and biological properties of new therapeutic-containing NPs for the sustainable delivery of 5-FU under simulated chronic wound conditions. In vitro experiments have been performed to assess the biocompatible character of these gelatin-based NPs in terms of their hemolytic and cytotoxicity properties. Due to hyperglycemia impact on both the chronicity of the wounds and chemotherapy efficacy, cellular responses have been determined under euglycemic and hyperglycemic conditions. In vitro cytotoxicity studies have reported good selective toxicity against the A431 cell line, demonstrating that gelatin-based NPs are promising dual-responsive delivery systems to SCC targeting under simulated chronic wound conditions

A bacterial acetyltransferase targets the protein kinase ZIP1, a positive regulator of plant immunity

Pseudomonas syringae is a model bacterial pathogen that penetrates the leaf to reach the plant apoplast, where it replicates causing disease. In order to do that, the pathogen must interfere and suppress a two-tiered plant defense response: PTI (PAMP-Triggered Immunity, or basal resistance) and ETI (Effector-Triggered Immunity). P. syringae uses a type III secretion system to directly deliver effector proteins inside the plant cell cytosol, many of which are known to suppress PTI, some of which are known to trigger ETI, and a handful of which are known to suppress ETI. Bacterial infection can also trigger a systemic plant defense response that protects the plant against additional pathogen attacks known as SAR (Systemic Acquired Resistance). We are particularly interested in the molecular and cellular mechanisms involved in effector-mediated defense evasion by P. syringae, in particular those involved in the suppression of ETI and SAR, and/or mediation of hormone signaling. Here we present data describing effector-mediated interference with plant immunity, by means of acetylation of a key positive regulator of local and systemic responses. Our work identifies a novel plant target for effector function, and characterizes its function. This work illustrates how analyzing the means by which a given effector interferes with its target can provide novel information regarding eukaryotic molecular mechanisms.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. MINECO BIO2015-64391R y FEDE