Scale in object and process ontologies

Scale is of great importance to the analysis of real world phenomena, be they enduring objects or perduring processes. This paper presents a new perspective on the concept of scale by considering it within two complementary ontological views. The first, called SNAP, recognizes enduring entities or objects, the other, called SPAN, perduring entities or processes. Within the meta-theory provided by the complementary SNAP and SPAN ontologies, we apply different theories of formal ontology such as mereology and granular partitions, and ideas derived from hierarchy theory. These theories are applied to objects and processes and form the framework within which we present tentative definitions of scale, which are found to differ between the two ontologies

Pharmaceutical consultation as a tool to improve health outcomes for patients with type 2 diabetes

This study develops and evaluates a pharmaceutical consultation program (PCP) to improve treatment for Type 2 diabetes patients (T2DP) and reduce risk factors for diabetic complications with possible application in other chronic diseases. We recruited T2DP receiving conventional medical treatment but with fasting glycemia >140mg/dl and/or glycated hemoglobin >7%. The PCP includes strategies obtained from Dader's method, the PWDT (Pharmacist's Workup of Drug Therapy method) model of pharmaceutical care, the SOAP (Subjective data, Objective data, Assessment, and Plan of care) method, and concepts based on a nursing care model. The PCP evaluated lifestyle, pharmacotherapy and monitoring it using laboratory tests, vital signs, and anthropometry. These procedures were repeated every 4 months for 1 year. Data obtained in each consultation were used to provide patient education focusing on healthy lifestyles and medications. Fifty patients completed the PCP. There were reductions in glycemia (PNeste estudo, desenvolvemos e avaliamos um programa de consulta farmacêutica (PCF) visando melhorar o tratamento de pacientes diabéticos tipo 2 (PDT2) e reduzir os fatores de risco de complicações diabéticas com possibilidade de aplicação em outras doenças crônicas. Para alcançar este propósito, PDT2 recebendo tratamento médico convencional, apresentando glicemia de jejum > 140 mg/dl e/ou hemoglobina glicada >7% foram selecionados. O PCF inclui estratégias obtidas a partir do método de Dader, do modelo de cuidados farmacêuticos PWDT (Pharmacist's Workup of Drug Therapy method), do método SOAP (Subjective data, Objective data, Assessment, and Plan of care) e conceitos baseados em um modelo de cuidados em enfermagem. O PCF avaliou o estilo de vida, farmacoterapia e seu monitoramento através de exames laboratoriais, sinais vitais e antropometria. Estes procedimentos foram repetidos a cada 4 meses durante 1 ano. Os dados obtidos em cada consulta possibilitaram oferecer educação focada no estilo de vida e uso de medicamentos. Para os 50 pacientes que concluiram o PCF houve redução da glicemia (P < 0.0001), hemoglobina glicada (P = 0.0022), colesterolemia (P = 0.0072), triacilgliceridemia (P= 0.0204) e pressão arterial (P < 0.0001). O aumento da concordância e a correção dos problemas relacionados a medicamentos contribuíram para melhoria do tratamento. Assim, podemos concluir que o PCF foi adequado para melhorar a saúde de PDT2 ao reduzir fatores de risco de complicações diabéticas

First measurement of the polarization observable E in the p→(γ→,π⁺)n reaction up to 2.25 GeV

First results from the longitudinally polarized frozen-spin target (FROST) program are reported. The double-polarization observable E, for the reaction $\vec \gamma \vec p \to \pi^+n$, has been measured using a circularly polarized tagged-photon beam, with energies from 0.35 to 2.37 GeV. The final-state pions were detected with the CEBAF Large Acceptance Spectrometer in Hall B at the Thomas Jefferson National Accelerator Facility. These polarization data agree fairly well with previous partial-wave analyses at low photon energies. Over much of the covered energy range, however, significant deviations are observed, particularly in the high-energy region where high-L multipoles contribute. The data have been included in new multipole analyses resulting in updated nucleon resonance parameters. We report updated fits from the Bonn-Gatchina, J\"ulich, and SAID groups.Comment: 6 pages, 3 figure

Near‐surface mean wind in Switzerland: Climatology, climate model evaluation and future scenarios

Near-surface seasonal and annual mean wind speed in Switzerland is investigated using homogenized observations, Twentieth Century Reanalysis (20CRv2c) data and raw model output of a 75 member EURO-COoRdinated Downscaling EXperiment regional climate model (RCM) ensemble for present day and future scenarios. The wind speed observations show a significant decrease in the Alps and on the southern Alpine slopes in the period 1981–2010. However, the 20CRv2c data reveal that the recent trends lie well within the decadal variability over longer time periods and no clear signs of a systematic wind stilling can be found for Switzerland. The ensemble of RCMs shows large biases in the annual mean wind speed over the Jura mountains, and some members also show large biases in the Alps compared to station observations. The spatial distribution of the model biases varies strongly between the RCMs, while the resolution and the driving global model have less impact on the pattern of the model bias. The RCMs are mostly able to represent the seasonality of wind speed on the Plateau but miss important details in complex terrain related to local wind systems. Most models show no significant changes in near-surface mean wind speed until the end of the 21st century. The model ensemble changes range from a 7% decrease to a 6% increase with an ensemble mean decrease of 1 to 2%. Due to model biases, the scale mismatch between model grid and station observations and the missing representation of local winds in the simulations, the changes need to be interpreted with utmost care. Future assessments might lead to major revisions even for the sign of the projected changes, in particular over complex terrain