724 research outputs found
Metabolic syndrome before puberty: Myth or reality?
Metabolic syndrome (MetS) is defined as a cluster of alterations related with insulin resistance (obesity, dyslipidemia, hypertension, and impaired glucose metabolism), which are associated with a higher risk of cardiovascular disease in adults. Several definitions have been proposed for older children and adolescents. However, no definitions have been made in accordance with pubertal status, and those in prepubertal state have not received attention enough, despite there are data suggesting the early presence of risk factors. The new insights concerning healthy and unhealthy metabolic status or the addition of novel metabolic risk biomarkers, may contribute to the knowledge about the development of MetS in children. This manuscript reviews the available evidence on MetS during childhood, focusing on the prepubertal period
Solution of coupled vertex and propagator Dyson-Schwinger equations in the scalar Munczek-Nemirovsky model
In a scalar model, we exactly solve the vertex and
propagator Dyson-Schwinger equations under the assumption of a spatially
constant (Munczek-Nemirovsky) propagator for the field. Various
truncation schemes are also considered.Comment: 7 pages,4 figures, minor changes, reference added for published
versio
Conformally flat spacetimes and Weyl frames
We discuss the concepts of Weyl and Riemann frames in the context of metric
theories of gravity and state the fact that they are completely equivalent as
far as geodesic motion is concerned. We apply this result to conformally flat
spacetimes and show that a new picture arises when a Riemannian spacetime is
taken by means of geometrical gauge transformations into a Minkowskian flat
spacetime. We find out that in the Weyl frame gravity is described by a scalar
field. We give some examples of how conformally flat spacetime configurations
look when viewed from the standpoint of a Weyl frame. We show that in the
non-relativistic and weak field regime the Weyl scalar field may be identified
with the Newtonian gravitational potential. We suggest an equation for the
scalar field by varying the Einstein-Hilbert action restricted to the class of
conformally-flat spacetimes. We revisit Einstein and Fokker's interpretation of
Nordstr\"om scalar gravity theory and draw an analogy between this approach and
the Weyl gauge formalism. We briefly take a look at two-dimensional gravity as
viewed in the Weyl frame and address the question of quantizing a conformally
flat spacetime by going to the Weyl frame.Comment: LATEX - 18 page
Effects of in-medium vector meson masses on low-mass dileptons from SPS heavy-ion collisions
Using a relativistic transport model to describe the expansion of the
fire-cylinder formed in the initial stage of heavy-ion collisions at SPS/CERN
energies, we study the production of dileptons with mass below about 1 GeV from
these collisions. The initial hadron abundance and their momentum distributions
in the fire-cylinder are determined by following the general features of the
results from microscopic models based on the string dynamics and further
requiring that the final proton and pion spectra and rapidity distributions are
in agreement with available experimental data. For dilepton production, we
include the Dalitz decay of , , , and
mesons, the direct decay of primary , and mesons, and
the pion-pion annihilation that proceeds through the meson, the
pion-rho annihilation that proceeds through the meson, and the
kaon-antikaon annihilation that proceeds through the meson. We find that
the modification of vector meson properties, especially the decrease of their
mass due to the partial restoration of chiral symmetry, in hot and dense
hadronic matter, provides a quantitative explanation of the recently observed
enhancement of low-mass dileptons by the CERES collaboration in central S+Au
collisions and by the HELIOS-3 collaboration in central S+W collisions.Comment: 46 pages, LaTeX, figures available from [email protected], to appear
in Nucl. Phys.
NN Core Interactions and Differential Cross Sections from One Gluon Exchange
We derive nonstrange baryon-baryon scattering amplitudes in the
nonrelativistic quark model using the ``quark Born diagram" formalism. This
approach describes the scattering as a single interaction, here the
one-gluon-exchange (OGE) spin-spin term followed by constituent interchange,
with external nonrelativistic baryon wavefunctions attached to the scattering
diagrams to incorporate higher-twist wavefunction effects. The short-range
repulsive core in the NN interaction has previously been attributed to this
spin-spin interaction in the literature; we find that these perturbative
constituent-interchange diagrams do indeed predict repulsive interactions in
all I,S channels of the nucleon-nucleon system, and we compare our results for
the equivalent short-range potentials to the core potentials found by other
authors using nonperturbative methods. We also apply our perturbative
techniques to the N and systems: Some
channels are found to have attractive core potentials and may accommodate
``molecular" bound states near threshold. Finally we use our Born formalism to
calculate the NN differential cross section, which we compare with experimental
results for unpolarised proton-proton elastic scattering. We find that several
familiar features of the experimental differential cross section are reproduced
by our Born-order result.Comment: 27 pages, figures available from the authors, revtex, CEBAF-TH-93-04,
MIT-CTP-2187, ORNL-CCIP-93-0
A Model for the Development of the Rhizobial and Arbuscular Mycorrhizal Symbioses in Legumes and Its Use to Understand the Roles of Ethylene in the Establishment of these two Symbioses
We propose a model depicting the development of nodulation and arbuscular mycorrhizae. Both processes are dissected into many steps, using Pisum sativum L. nodulation mutants as a guideline. For nodulation, we distinguish two main developmental programs, one epidermal and one cortical. Whereas Nod factors alone affect the cortical program, bacteria are required to trigger the epidermal events. We propose that the two programs of the rhizobial symbiosis evolved separately and that, over time, they came to function together. The distinction between these two programs does not exist for arbuscular mycorrhizae development despite events occurring in both root tissues. Mutations that affect both symbioses are restricted to the epidermal program. We propose here sites of action and potential roles for ethylene during the formation of the two symbioses with a specific hypothesis for nodule organogenesis. Assuming the epidermis does not make ethylene, the microsymbionts probably first encounter a regulatory level of ethylene at the epidermis–outermost cortical cell layer interface. Depending on the hormone concentrations there, infection will either progress or be blocked. In the former case, ethylene affects the cortex cytoskeleton, allowing reorganization that facilitates infection; in the latter case, ethylene acts on several enzymes that interfere with infection thread growth, causing it to abort. Throughout this review, the difficulty of generalizing the roles of ethylene is emphasized and numerous examples are given to demonstrate the diversity that exists in plants
Co-infections and superinfections complicating COVID-19 in cancer patients: A multicentre, international study
Background: We aimed to describe the epidemiology, risk factors, and clinical outcomes of co-infections and superinfections in onco-hematological patients with COVID-19. Methods: International, multicentre cohort study of cancer patients with COVID-19. All patients were included in the analysis of co-infections at diagnosis, while only patients admitted at least 48 h were included in the analysis of superinfections. Results: 684 patients were included (384 with solid tumors and 300 with hematological malignancies). Co-infections and superinfections were documented in 7.8% (54/684) and 19.1% (113/590) of patients, respectively. Lower respiratory tract infections were the most frequent infectious complications, most often caused by Streptococcus pneumoniae and Pseudomonas aeruginosa. Only seven patients developed opportunistic infections. Compared to patients without infectious complications, those with infections had worse outcomes, with high rates of acute respiratory distress syndrome, intensive care unit (ICU) admission, and case-fatality rates. Neutropenia, ICU admission and high levels of C-reactive protein (CRP) were independent risk factors for infections. Conclusions: Infectious complications in cancer patients with COVID-19 were lower than expected, affecting mainly neutropenic patients with high levels of CRP and/or ICU admission. The rate of opportunistic infections was unexpectedly low. The use of empiric antimicrobials in cancer patients with COVID-19 needs to be optimized
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