Динамика экономических отношений в системе «лес – человек» как фактор формирования менталитета восточных славян

Материалы VIIІ междунар. науч. конф., 23-24 мая 2013 г

Developmental and hormonal regulation of direct shoot organogenesis and somatic embryogenesis in sugarcane (Saccharum spp. interspecific hybrids) leaf culture

Rapid and efficient in vitro regeneration methods\ud that minimise somaclonal variation are critical for the\ud genetic transformation and mass propagation of commercial\ud varieties. Using a transverse thin cell layer culture\ud system, we have identified some of the developmental and\ud physiological constraints that limit high-frequency regeneration\ud in sugarcane leaf tissue. Tissue polarity and consequently\ud the orientation of the explant in culture, size and\ud developmental phase of explant, and auxin concentration\ud play a significant role in determining the organogenic potential\ud of leaf tissue in culture. Both adventitious shoot\ud production and somatic embryogenesis occurred on the\ud proximal cut surface of the explant, and a regeneration\ud gradient, decreasing gradually from the basal to the distal\ud end, exists in the leaf roll. Importantly, auxin, when\ud added to the culture medium, reduced this spatial developmental\ud constraint, as well as the effect of genotype on\ud plant regeneration. Transverse sections (1–2 mm thick) ob-\ud tained from young leaf spindle rolls and orienting explants\ud with its distal end facing the medium (directly in contact\ud with medium) are critical for maximum regeneration.\ud Shoot regeneration was observed as early as 3 weeks on\ud MS medium supplemented with α-naphthalenencetic acid\ud (NAA) and 6-benzyladenine, while somatic embryogenesis\ud or both adventitious shoot organogenesis and somatic embryogenesis\ud occurred on medium with NAA and chlorophenoxyacetic\ud acid. Twenty shoots or more could be generated\ud from a single transverse section explant. These shoots regenerated\ud roots and successfully established after transplanted\ud to pots. Large numbers of plantlets can be regenerated\ud directly and rapidly using this system. SmartSettr,\ud the registered name for this process and the plants produced,\ud will have significant practical applications for the\ud mass propagation of new cultivars and in genetic modification\ud programs. The SmartSettr system has already\ud been used commercially to produce substantial numbers\ud of plants of orange rust-resistant and new cultivars in\ud Australia

Antenna-coupled arrays of voltage-biased superconducting bolometers

We report on the development of antenna-coupled Voltage-biased Superconducting Bolometers (VSBs) which use Transition-edge Sensors (TES). Antenna coupling can greatly simplify the fabrication of large multi-frequency bolometer arrays compared to horn-coupled techniques. This simplification can make it practical to implement 1000+ element arrays that fill the focal plane of mm/sub-mm wave telescopes. We have designed a prototype device with a double-slot dipole antenna, integrated band-defining filters, and a membrane-suspended bolometer. A test chip has been constructed and will be tested shortly

Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA‐AA recommendations for the neuropathologic diagnosis of Alzheimer’s disease

IntroductionPerformance of the amyloid tracer [18F]flutemetamol was evaluated against three pathology standard of truth (SoT) measures including neuritic plaques (CERAD “original” and “modified” and the amyloid component of the 2012 NIA‐AA guidelines).MethodsAfter [18F]flutemetamol imaging, 106 end‐of‐life patients who died underwent postmortem brain examination for amyloid plaque load. Blinded positron emission tomography scan interpretations by five independent electronically trained readers were compared with pathology measures.ResultsBy SoT, sensitivity and specificity of majority image interpretations were, respectively, 91.9% and 87.5% with “original CERAD,” 90.8% and 90.0% with “modified CERAD,” and 85.7% and 100% with the 2012 NIA‐AA criteria.DiscussionThe high accuracy of either CERAD criteria suggests that [18F]flutemetamol predominantly reflects neuritic amyloid plaque density. However, the use of CERAD criteria as the SoT can result in some false‐positive results because of the presence of diffuse plaques, which are accounted for when the positron emission tomography read is compared with the 2012 NIA‐AA criteria.HighlightsDetermination of the accuracy of [18F]flutemetamol image read against Aβ at autopsy.High sensitivity and specificity to 3 neuropathologic criteria as Standards of Truth.Images are 100% specific when the SoT reflects both neuritic and diffuse plaques.This study has the largest autopsy validation cohort for Aβ PET tracers to date.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152734/1/dad2jdadm201706001.pd

Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo

International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100−105 M⊙, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass ∼150 M⊙ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200 M⊙ and effective aligned spin 0.8 at 0.056 Gpc−3 yr−1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpc−3 yr−1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]† Deceased, August 2020