2,359 research outputs found

    Peak-constrained least-squares optimization

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    Jet measurements in the ALICE experiment at the LHC

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    Jet tomography probes provide a means to explore the properties of highly compressed and excited nuclear matter created in heavy ion collisions. The capabilities of the ALICE experiment, with its electromagnetic calorimeter (EMCal) upgrade, to trigger on and reconstruct jets in p+p and Pb+Pb collisions at sNN\sqrt{s_{NN}}=5.5 TeV are presented.Comment: 8 pages, 6 figures. Presented at the IX International Conference on Nucleus-Nucleus Collisions, Rio de Janeiro, Brazil, August 28 - September 1, 200

    Di-hadron azimuthal correlation and Mach-like cone structure in parton/hadron transport model

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    In the framework of a multi-phase transport model (AMPT) with both partonic and hadronic interactions, azimuthal correlations between trigger particles and associated scattering particles have been studied by the mixing-event technique. The momentum ranges of these particles are 3<pTtrig<63< p^{trig}_T< 6 GeV/cc and 0.15<pTassoc<30.15< p_{T}^{assoc} < 3 GeV/cc (soft), or 2.5<pTtrig<2.5<p^{trig}_T< 4 GeV/cc and 1<pTassoc<2.51< p_{T}^{assoc} < 2.5 GeV/cc (hard) in Au + Au collisions at sNN\sqrt{s_{NN}} = 200 GeV. A Mach-like structure has been observed in correlation functions for central collisions. By comparing scenarios with and without parton cascade and hadronic rescattering, we show that both partonic and hadronic dynamical mechanisms contribute to the Mach-like structure of the associated particle azimuthal correlations. The contribution of hadronic dynamical process can not be ignored in the emergence of Mach-like correlations of the soft scattered associated hadrons. However, hadronic rescattering alone cannot reproduce experimental amplitude of Mach-like cone on away-side, and the parton cascade process is essential to describe experimental amplitude of Mach-like cone on away-side. In addition, both the associated multiplicity and the sum of pTp_{T} decrease, whileas the increases, with the impact parameter in the AMPT model including partonic dynamics from string melting scenario.Comment: 9 pages, 5 figures; Physics Letters B 641, 362-367 (2006

    Large Deviations in the Superstable Weakly Imperfect Bose Gas

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    The superstable Weakly Imperfect Bose Gas {(WIBG)} was originally derived to solve the inconsistency of the Bogoliubov theory of superfluidity. Its grand-canonical thermodynamics was recently solved but not at {point of} the {(first order)} phase transition. This paper proposes to close this gap by using the large deviations formalism and in particular the analysis of the Kac distribution function. It turns out that, as a function of the chemical potential, the discontinuity of the Bose condensate density at the phase transition {point} disappears as a function of the particle density. Indeed, the Bose condensate continuously starts at the first critical particle density and progressively grows but the free-energy per particle stays constant until the second critical density is reached. At higher particle densities, the Bose condensate density as well as the free-energy per particle both increase {monotonously}

    Understanding Divertor Detachment through CRETIN Modeling - a Work in Progress

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    From numerous studies aimed at reducing the divertor target plate incident heat flux or understanding divertor detachment, an abundance of evidence supporting the importance of atomic processes in tokamak plasmas now exists. Through use of a multi-dimensional Non-Local Thermodynamic Equilibrium (NLTE) simulation code named CRETIN [1] this repor

    The effects of central cholecystokinin receptor blockade on hypothalamic-pituitary-adrenal and symptomatic responses to overnight withdrawal from alprazolam

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142739/1/Abelson-Nesse-alprazolam-BioPsych-1995.pd

    Advancing current approaches to disease management evaluation:Capitalizing on heterogeneity to understand what works and for whom

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    BACKGROUND: Evaluating large-scale disease management interventions implemented in actual health care settings is a complex undertaking for which universally accepted methods do not exist. Fundamental issues, such as a lack of control patients and limited generalizability, hamper the use of the ‘gold-standard’ randomized controlled trial, while methodological shortcomings restrict the value of observational designs. Advancing methods for disease management evaluation in practice is pivotal to learn more about the impact of population-wide approaches. Methods must account for the presence of heterogeneity in effects, which necessitates a more granular assessment of outcomes. METHODS: This paper introduces multilevel regression methods as valuable techniques to evaluate ‘real-world’ disease management approaches in a manner that produces meaningful findings for everyday practice. In a worked example, these methods are applied to retrospectively gathered routine health care data covering a cohort of 105,056 diabetes patients who receive disease management for type 2 diabetes mellitus in the Netherlands. Multivariable, multilevel regression models are fitted to identify trends in clinical outcomes and correct for differences in characteristics of patients (age, disease duration, health status, diabetes complications, smoking status) and the intervention (measurement frequency and range, length of follow-up). RESULTS: After a median one year follow-up, the Dutch disease management approach was associated with small average improvements in systolic blood pressure and low-density lipoprotein, while a slight deterioration occurred in glycated hemoglobin. Differential findings suggest that patients with poorly controlled diabetes tend to benefit most from disease management in terms of improved clinical measures. Additionally, a greater measurement frequency was associated with better outcomes, while longer length of follow-up was accompanied by less positive results. CONCLUSIONS: Despite concerted efforts to adjust for potential sources of confounding and bias, there ultimately are limits to the validity and reliability of findings from uncontrolled research based on routine intervention data. While our findings are supported by previous randomized research in other settings, the trends in outcome measures presented here may have alternative explanations. Further practice-based research, perhaps using historical data to retrospectively construct a control group, is necessary to confirm results and learn more about the impact of population-wide disease management
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