Evaluación de los parámetros antropométricos en una muestra nacional de adultos mayores mexicanos

The purpose of this study was to describe anthropometric parameters in a population of Mexican older adults (OA). 516 OA (277 women, 239 men) aged ≥ 65 years were interviewed. Anthropometry and a sociodemographic data questionnaire were performed. Means and standard deviations, prevalence (%) and confidence intervals are reported in the results. SPSS v20.0 was used in the statistical analysis. The combined prevalence of overweight and obesity in our population was 77%. The mean WHR values obtained were (0.97 in men and 0.89 in women). Finally, the percentage of fat in men was 30.6% and in women it was 39.8%. The results of this investigation showed significant differences between men and women in most of the anthropometric measures and nutrition indicators. The prevalence of overweight and obesity reported in the Mexican elderly population was higher than that reported in other studies, which shows an important public health problem in Mexican older adults. More studies are needed at the national level on nutritional parameters in the elderly in order to detect cardiovascular risk factors in a timely manner.El propósito de este estudio fue describir los parámetros antropométricos en una población de adultos mayores (AM) mexicanos. Se entrevistó a 516 AM (277 mujeres, 239 hombres) con ≥ 65 años de edad. Se realizó antropometría, y un cuestionario de datos sociodemográficos. En los resultados se reportan medias y desviaciones estándar, prevalencias (%) e intervalos de confianza. En el análisis estadístico se utilizó el SPSS v20.0. La prevalencia conjunta de sobrepeso y obesidad en nuestra población fue de 77%. Los valores medios de Indice Cintura-Cadera obtenidos fueron (0.97 hombres y 0.89 en mujeres). Por último, el porcentaje de grasa en hombres fue 30.6 % y en mujeres fue 39.8 %. Los resultados de esta investigación arrojaron diferencias significativas entre hombres y mujeres en la mayoría de las medidas antropométricas e indicadores de nutrición. La prevalencia de sobrepeso y obesidad reportada en la población mexicana de edad avanzada fue más alta que lo reportado en otros estudios, lo que muestra un importante problema de salud pública en los en adultos mayores mexicanos. Se requieren más estudios a nivel nacional sobre los parámetros nutricionales en AM con el fin de detectar de forma oportuna factores de riesgo cardiovascular.Actividad Física y Deport

Visión integral de la farmacología de los inhibidores de los co-transportadores de sodio/glucosa: pasado, presente y futuro

La búsqueda de nuevas alternativas para el tratamiento de la diabetes mellitus (DM) ha tomado un papel protagónico en la investigación preclínica y clínica actual en el ámbito endocrino-metabólico a la luz del panorama epidemiológico severo marcado por esta enfermedad. Las tendencias contemporáneas en el manejo de la DM enfatizan la adopción de una perspectiva centrada en el paciente, con la prescripción de esquemas terapéuticos personalizados. La introducción de nuevos fármacos, como los inhibidores del co-transportadores de Na+/glucosa 2 (SGLT2i) o “gliflozinas”, ha revitalizado el panorama terapéutico de la DM en este sentido. Estos fármacos han mostrado alta eficacia en el control metabólico con un perfil de tolerabilidad razonable, lo cual les ha conferido una rápida aceptación en las recomendaciones actuales para el manejo de la DM. El uso de los SGLT2i resulta en un efecto glucosúrico que se acompaña de la activación de mecanismos contrarreguladores de la glicemia y otros cambios endocrinos que favorecen el control de la DM. Sin embargo, esta inhibición muestra muchos beneficios añadidos, especialmente en el intestino, al combinarse con la inhibición de SGLT1. Además, se han estudiado algunas gliflozinas para otras indicaciones distintas a la DM como la obesidad, el síndrome de ovarios poliquísticos y la constipación. Esta revisión resume los fundamentos farmacológicos de la inhibición de SGLT2 y SGLT1, y las oportunidades que se avizoran en el futuro con estos agentes

Visión integral de la farmacología de los inhibidores de los co-transportadores de sodio/glucosa: pasado, presente y futuro

La búsqueda de nuevas alternativas para el tratamiento de la diabetes mellitus (DM) ha tomado un papel protagónico en la investigación preclínica y clínica actual en el ámbito endocrino-metabólico a la luz del panorama epidemiológico severo marcado por esta enfermedad. Las tendencias contemporáneas en el manejo de la DM enfatizan la adopción de una perspectiva centrada en el paciente, con la prescripción de esquemas terapéuticos personalizados. La introducción de nuevos fármacos, como los inhibidores del co-transportadores de Na+/glucosa 2 (SGLT2i) o “gliflozinas”, ha revitalizado el panorama terapéutico de la DM en este sentido. Estos fármacos han mostrado alta eficacia en el control metabólico con un perfil de tolerabilidad razonable, lo cual les ha conferido una rápida aceptación en las recomendaciones actuales para el manejo de la DM. El uso de los SGLT2i resulta en un efecto glucosúrico que se acompaña de la activación de mecanismos contrarreguladores de la glicemia y otros cambios endocrinos que favorecen el control de la DM. Sin embargo, esta inhibición muestra muchos beneficios añadidos, especialmente en el intestino, al combinarse con la inhibición de SGLT1. Además, se han estudiado algunas gliflozinas para otras indicaciones distintas a la DM como la obesidad, el síndrome de ovarios poliquísticos y la constipación. Esta revisión resume los fundamentos farmacológicos de la inhibición de SGLT2 y SGLT1, y las oportunidades que se avizoran en el futuro con estos agentes

Glomalin accumulated in seagrass sediments reveals past alterations in soil quality due to land-use change

Arbuscular mycorrhizal fungi (AMF), symbionts with most terrestrial plants, produce glomalin-related soil protein (GRSP),which plays a major role in soil structure and quality. Both fungi hyphae and protein production in soils are affected by perturbations related to land-use changes, implying that GRSP is a sensitive indicator of soil quality. Unfortunately, GRSP degrades within years to decades in oxic environments, preventing its use as palaeoecological proxy. However, GRSP is transported to marine, near-shore anoxic sediments, where it accumulates and remains non-degraded, enabling the assessment of its potential as a palaeoecological proxy for soil ecosystem's health. Exploiting this fact, we have obtained for the first time a long-term record (c. 1250 years) of GRSP content using a Posidonia oceanica seagrass mat sediment core from the Western Mediterranean (Portlligat Bay, Spain). The trends in GRSP content matchedwellwith land-use changes related to agrarian activities reconstructed by pollen analysis. In periods of cultivation, GRSP accumulation in the mat decreased. Given the role played by GRSP, the results suggest that agrarian intensification may have resulted in perturbations to soil quality. Thus, GRSP in seagrass mat sediments can be used to assess long-term trends in continental soil quality induced by human activities. These findings open new possibilities in long-term ecology research, as other anoxic environments could be potentially valid too. Testing them would open the possibility to identify long-termpatterns in soil quality and other environmental stressors that could also affect AMF and GRSP production in soils

Global dataset of soil organic carbon in tidal marshes

Funding: W.E.N.A. and C.S. would like to acknowledge funding support from the Scottish Government and UK Natural Environment Research Council C-SIDE project (grant NE/R010846/1).Tidal marshes store large amounts of organic carbon in their soils. Field data quantifying soil organic carbon (SOC) stocks provide an important resource for researchers, natural resource managers, and policy-makers working towards the protection, restoration, and valuation of these ecosystems. We collated a global dataset of tidal marsh soil organic carbon (MarSOC) from 99 studies that includes location, soil depth, site name, dry bulk density, SOC, and/or soil organic matter (SOM). The MarSOC dataset includes 17,454 data points from 2,329 unique locations, and 29 countries. We generated a general transfer function for the conversion of SOM to SOC. Using this data we estimated a median (± median absolute deviation) value of 79.2±38.1 Mg SOC ha−1 in the top 30cm and 231±134 Mg SOC ha−1 in the top 1m of tidal marsh soils globally. This data can serve as a basis for future work, and may contribute to incorporation of tidal marsh ecosystems into climate change mitigation and adaptation strategies and policies.Publisher PDFPeer reviewe

Global dataset of soil organic carbon in tidal marshes.

Funder: The Nature Conservancy through the Bezos Earth Fund and other donor supportFunder: Nelson Mandela UniversityFunder: State Research Agency of Spain (AEI; CGL2007-64915), the Mancomunidad de los Canales del Taibilla (MCT), and the Science and Technology Agency of the Murcia Region (Seneca Foundation; 00593/PI/04 & 08739/PI/08).Funder: Scottish Government and UK Natural Environment Research Council C-SIDE project (grant NE/R010846/1)Funder: COOLSTYLE/CARBOSTORE projectFunder: New Zealand Ministry for Business, Innovation and Employment Contract #C01X2109Funder: Portuguese national funds from FCT - Foundation for Science and Technology through projects UIDB/04326/2020, UIDP/04326/2020, LA/P/0101/2020, and 2020.03825.CEECINDFunder: German Research Foundation (DFG project number: GI 171/25-1)Funder: State Research Agency of Spain (AEI; CGL2007-64915), the Mancomunidad de los Canales del Taibilla (MCT), the Science and Technology Agency of the Murcia Region (Seneca Foundation; 00593/PI/04 & 08739/PI/08), and a Ramón y Cajal contract from the Spanish Ministry of Science and Innovation (RYC2020-029322-I)Funder: Velux foundation (#28421, Blå Skove – Havets Skove som kulstofdræn)Funder: LIFE ADAPTA BLUES project Ref. LIFE18 CCA/ES/001160Funder: LIFE ADAPTA BLUES project Ref. LIFE18 CCA/ES/001160, support of national funds through Fundação para a Ciência e Tecnologia, I.P. (FCT), under the projects UIDB/04292/2020, UIDP/04292/2020, granted to MARE, and LA/P/0069/2020, granted to the Associate Laboratory ARNETFunder: Financial support provided by the Welsh Government and Higher Education Funding Council for Wales through the Sêr Cymru National Research Network for Low Carbon, Energy and Environment; as well as the Spanish Ministry of Science and Innovation (project PID2020-113745RB-I00) and FEDERFunder: South African Department of Science and Innovation (DSI)—National Research Foundation (NRF) Research Chair in Shallow Water Ecosystems (UID: 84375), and the Nelson Mandela UniversityFunder: I+D+i projects RYC2019-027073-I and PIE HOLOCENO 20213AT014 funded by MCIN/AEI/10.13039/501100011033 and FEDERFunder: Funding support from the Scottish Government and UK Natural Environment Research Council C-SIDE project (grant NE/R010846/1)Funder: Xunta de Galicia (GRC project IN607A 2021-06)Funder: U.S. Army Engineering, Research and Development Center (ACTIONS project, W912HZ2020070)Tidal marshes store large amounts of organic carbon in their soils. Field data quantifying soil organic carbon (SOC) stocks provide an important resource for researchers, natural resource managers, and policy-makers working towards the protection, restoration, and valuation of these ecosystems. We collated a global dataset of tidal marsh soil organic carbon (MarSOC) from 99 studies that includes location, soil depth, site name, dry bulk density, SOC, and/or soil organic matter (SOM). The MarSOC dataset includes 17,454 data points from 2,329 unique locations, and 29 countries. We generated a general transfer function for the conversion of SOM to SOC. Using this data we estimated a median (± median absolute deviation) value of 79.2 ± 38.1 Mg SOC ha-1 in the top 30 cm and 231 ± 134 Mg SOC ha-1 in the top 1 m of tidal marsh soils globally. This data can serve as a basis for future work, and may contribute to incorporation of tidal marsh ecosystems into climate change mitigation and adaptation strategies and policies

Database: Tidal Marsh Soil Organic Carbon (MarSOC) Dataset

The repository is formatted in the following structure: - README.md: markdown file with repository description - MarSOC-Dataset.Rproj: R project file - useful when using RStudio - Maxwell_MarSOC_dataset.csv: .csv file containing the final dataset. The data structure is described in the metadata file. It contains 17,454 records distributed amongst 29 countries. - Maxwell_MarSOC_dataset_metadata.csv: .csv file containing the main data file metadata (equivalent to Table 1). - data_paper/: folder containing the list of studies included in the dataset, as well as figures for this data paper (generated from the following R script: ‘reports/04_data_process/scripts/04_data-paper_data_clean.R’). - reports/01_litsearchr/: folder containing .bib files with references from the original naive search, a .Rmd document describing the litsearchr analysis using nodes to go from the naive search to the final search string, and the .bib files from this final search, which were then imported into sysrev for abstract screening. - reports/02_sysrev/: folder with .csv files exported from sysrev after abstract screening. These files contain the included studies with their various labels. - reports/03_data_format/: folder containing all original data, associated scripts, and exported data. - reports/04_data_process/: folder containing data processing scripts to bind and clean the exported data, as well as a script testing the different models for predicting soil organic carbon from organic matter and finalising the equation using all available data. A script testing and removing outliers is also included