Projeto de intervenção para melhorar a abordagem da hipertensão arterial dos pacientes da ESF Amoroso Costa

Uberaba é um município com uma população aproximadamente de 318 813 habitantes. O município tem o sistema organizado por níveis de atenção os quais constituem a rede de atenção de saúde da população. A Hipertensão arterial, entre as doenças crônicas, é um dos principais problemas de saúde em países desenvolvidos e o controle é sobre a qual devemos atuar para diminuir significativamente a morbidade por complicaçoes da doença. O estudo foi feito na área da equipe Amoroso Costa da Unidade de Saúde Jacob Jose Pinto no município Uberaba do estado Minas Gerais. Este estudo tem como objetivo elaborar um projeto de intervenção para corrigir a falta de adesão ao tratamento de pacientes hipertensos da equipe de saúde familiar Amoroso Costa. Os problemas analisados pela equipe de saude junto com as pessoas que conhecem a área e que tem domínio dos problemas de sáude existentes em cada microarea, e das suas possíveis causas e consequências. Com este trabalho esperamos elevar os conhecimentos dos usuários e a equipe de trabalho sobre o controle da doença, aumentar a qualidade das atividades do grupo e melhorar a relação dos usuários com a equip

Contrasting patterns of selection between MHC I and II across populations of Humboldt and Magellanic penguins

Indexación: Web of ScienceThe evolutionary and adaptive potential of populations or species facing an emerging infectious disease depends on their genetic diversity in genes, such as the major histocompatibility complex (MHC). In birds, MHC class I deals predominantly with intracellular infections (e.g., viruses) and MHC class II with extracellular infections (e.g., bacteria). Therefore, patterns of MHC I and II diversity may differ between species and across populations of species depending on the relative effect of local and global environmental selective pressures, genetic drift, and gene flow. We hypothesize that high gene flow among populations of Humboldt and Magellanic penguins limits local adaptation in MHC I and MHC II, and signatures of selection differ between markers, locations, and species. We evaluated the MHC I and II diversity using 454 next-generation sequencing of 100 Humboldt and 75 Magellanic penguins from seven different breeding colonies. Higher genetic diversity was observed in MHC I than MHC II for both species, explained by more than one MHC I loci identified. Large population sizes, high gene flow, and/or similar selection pressures maintain diversity but limit local adaptation in MHC I. A pattern of isolation by distance was observed for MHC II for Humboldt penguin suggesting local adaptation, mainly on the northernmost studied locality. Furthermore, trans species alleles were found due to a recent speciation for the genus or convergent evolution. High MHC I and MHC II gene diversity described is extremely advantageous for the long term survival of the species.http://onlinelibrary.wiley.com/doi/10.1002/ece3.2502/epd

Percepcion de los docentes participantes del Programa Escuelas Focalizadas Completas de la Provincia de Talca, respecto al Programa de Ensenanza

122 p.Desde principios de los años 90 el Ministerio de Educación se ha dado cuenta que una educación de calidad abre una serie de oportunidades a los integrantes de la sociedad. Es por este motivo que el gobierno viene implementando un conjunto de programas para el mejoramiento de la educación, entre los que se encuentra las Escuelas Focalizadas Completas, el cual tiene a los docentes como su principal agente para elevar el nivel de la educación. La Secretaría Ministerial de educación se encuentra especialmente interesada en conocer la forma de cómo los docentes ven el programa, para entender los resultados que ha tenido éste hasta el momento, pudiendo evaluar decisiones respecto a su futuro y el de los próximos programas. El objetivo del presente estudio es conocer la percepción de los docentes participantes del programa Escuelas Focalizadas Completas de la provincia de Talca, respecto al programa de enseñanza utilizado. Para dar respuesta a esto es que se planteó un objetivo general más una serie de objetivos específicos, basados en la información de las entrevistas con expertos y grupos foco. La investigación se dividió en dos partes, una primera del tipo exploratoria que recolectó información para diseñar el instrumento de medición y una segunda parte concluyente descriptiva de corte transversal, que permite hacer inferencias acerca de lo que se busca medir. La investigación abarcó las diez comunas pertenecientes a la provincia de Talca, con cuya información se realizaron análisis univariados, bivariados, y factorial. La docencia en las Escuelas Focalizadas Completas de la provincia de Talca es realizada mayoritariamente por mujeres y la participación masculina en ellas representa casi un tercio de de la población total. Un segundo dato de importancia, es que gran parte de los docentes sobrepasa los 50 años de edad y los 30 años de servicio

Body Composition and Blood Biomarkers Correlate with Muscle Strength and Anaerobic Performance

Blood biomarkers and body composition are sensitive indicators to monitor and predict performance in the athletic population. The analysis of these markers can help monitor progression in athletes competing in aerobic and anaerobic sports; however, it is unclear which biomarkers are associated with muscle strength and anaerobic performance. PURPOSE: To explore the correlations of body composition and blood biomarkers with muscle strength and power tests of the countermovement jump (CMJ), broad jump (BJ), isometric mid-thigh pulls (IMTP), hand grip strength (HGS), and the Wingate anaerobic test. METHODS: This study recruited nine collegiate intramural sports club students (Height=171.43±10.05 cm, Weight=70.36±13.18 kg, Age=23.87±3.65 years). Body composition was assessed with air displacement plethysmography (BodPod), and muscular strength was measured by IMTP and HGS. Muscular power was assessed via CMJ and BJ and calculated from ground reaction forces. Additionally, peak power output and mean power output were determined from the 30-second Wingate test. Blood biomarkers of hemoglobin (Hb), red blood cell count (RBC), and hematocrit (Hct) were analyzed by Quest Diagnostics. Data normality was confirmed with a Shapiro-Wilk test. Pearson-R correlations were conducted to determine associations between body composition, blood biomarkers, and the above performance tests. Significance was set at an alpha level of p\u3c0.05. RESULTS: Fat free mass was positively correlated with BJ distance (r=0.805, p=0.016), IMTP peak force (r=0.907, p=0.002), Wingate peak power (r=0.708, p=0.049), and Wingate mean power (r=0.910, p=0.002). Additionally, body fat percentage was negatively associated with IMTP peak force (r=-0.850, p=0.008) and mean power in the Wingate (r=-0.800, p=0.017). There was a positive correlation between blood biomarkers (RBC, Hb, and Hct) and mean power of the Wingate (r=0.693-0.906, p\u3c0.05), and peak force of the IMTP (r=0.710–0.833, p\u3c0.05). Furthermore, RBC was found positively correlated with CMJ height (r=0.815, p=0.007) and BJ distance (r=0.763, p=0.028), while HGS was positively associated with RBC (r=0.910, p=0.012) and Hct (r=0.962, p=0.002). CONCLUSION: Body composition and blood biomarkers correlate with muscle strength, power, and anaerobic performance, which could be potentially used to monitor and predict human performance in athletes

Genome Sequence of Borrelia chilensis VA1, a South American Member of the Lyme Borreliosis Group

Borrelia chilensis strain VA1 is a recently described South American member of the Borrelia burgdorferi sensu lato complex from Chile. Whole-genome sequencing analysis determined its linear chromosome and plasmids lp54 and cp26, confirmed its membership in the Lyme borreliosis group, and will open new research avenues regarding its pathogenic potential

Mechanical properties and electrical surface charges of microfibrillated cellulose/imidazole-modified polyketone composite membranes

In the present work, microfibrillated cellulose (MFC) suspensions were produced by high-pressure homogenization and subsequently used to fabricate MFC membranes (C-1) by vacuum filtration followed by hot-pressing. A polyketone (PK50) was chemically modified by Paal-Knorr reaction to graft imidazole (IM) functional groups along its backbone structure. The resulting polymer is referred to as PK50IM80. By solution impregnation, C-1 was immersed in an aqueous solution of PK50IM80 and subsequently hot pressed, resulting in the fabrication of MFC/PK50IM80 composite membranes (C-IMP). Another method, referred to as solution mixing, consisted in adding MFC into an aqueous solution of PK50IM80 followed by vacuum filtration and hot-pressing to obtain MFC/PK50IM80 composite membranes (C-MEZC). C-IMP and C-MEZC were characterized by a wide range of analytical techniques including, X-ray photoelectron spectroscopy, Fourier-transform infrared chemical imaging, scanning electron microscopy, atomic force microscopy, dynamical mechanical analysis, tensile testing as well as streaming zeta potential, and compared to C-1 (reference material). The results suggested that C-IMP possess a more homogeneous distribution of PK50IM80 at their surface compared to C-MEZC. C-IMP was found to possess significantly enhanced Young's modulus compared to C-1 and C-MEZC. The tensile strength of C-IMP was found to improve significantly compared to C-1, whereas C-1 possessed significantly higher tensile index than C-IMP and C-MEZC. Furthermore, the presence of PK50IM80 at the surface of MFC was found to significantly shift the isoelectric point (IEP) of the membranes from pH 2.3 to a maximum value of 4.5 for C-IMP. Above the IEP, C-IMP and C-MEZC were found to possess significantly less negative electrical surface charges (plateau value of -25 mV at pH 10) when compared to C-1 (plateau value of -42 mV at pH 10). Our approach may have implication to broaden the range of filtration applications of MFC-based membranes

Borrelia Chilensis, a New Member of the Borrelia Burgdorferi Sensu Lato Complex That Extends the Range of This Genospecies in the Southern Hemisphere

Borrelia burgdorferi sensu lato (s.l.), transmitted by Ixodes spp. ticks, is the causative agent of Lyme disease. Although Ixodes spp. ticks are distributed in both Northern and Southern Hemispheres, evidence for the presence of B. burgdorferi s.l. in South America apart from Uruguay is lacking. We now report the presence of culturable spirochetes with flat-wave morphology and borrelial DNA in endemic Ixodes stilesi ticks collected in Chile from environmental vegetation and long-tailed rice rats (Oligoryzomys longicaudatus). Cultured spirochetes and borrelial DNA in ticks were characterized by multilocus sequence typing and by sequencing five other loci (16S and 23S ribosomal genes, 5S-23S intergenic spacer, flaB, ospC). Phylogenetic analysis placed this spirochete as a new genospecies within the Lyme borreliosis group. Its plasmid profile determined by polymerase chain reaction and pulsed-field gel electrophoresis differed from that of B. burgdorferi B31A3. We propose naming this new South American member of the Lyme borreliosis group B. chilensis VA1 in honor of its country of origin

Bifidobacterium bacteraemia is rare with routine probiotics use in preterm infants: A further case report with literature review

Prophylactic administration of oral probiotics is associated with significant reductions in the morbidity and mortality of necrotising enterocolitis in preterm infants. We document the first case of Bifidobacterium longum subsp. infantis sub-clinical bacteraemia, in an extremely low birth weight preterm infant, since introduction of routine probiotic treatment at the Norfolk and Norwich University Hospital 10 years ago. Whole genome comparisons confirmed the isolated strain likely originated from the probiotic product