Evaluation of cross-contamination of nylon bags with heavy loaded gasoline fire debris and with automotive paint thinner

Nylon bags are used for packaging fire debris in several countries, particularly in Europe. The possibility of cross-contamination during transport from the fire scene to the laboratory, in normal casework conditions in the UK, was studied for two brands of nylon bags, using simulated heavy loaded fire debris. Three experiments were carried out with each brand, using as sample a piece of cotton fabric soaked with gasoline. One experiment was carried out using automotive paint thinner (oxygenated solvent). Each sample was sealed in a nylon bag and stored in contact with eight empty bags. The empty bags were analysed at regular intervals for a period of time up to eight weeks, using SPME and GC/MS. Cross-contamination was found for components of gasoline (toluene and C2-alkylbenzenes) in the two brands of nylon bags used, after 4 days and 2 weeks. Cross contamination using automotive topcoat thinner was detected after 2 days

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

The nematode Caenorhabditis elegans has emerged as an important animal model in various fields including neurobiology, developmental biology, and genetics. Characteristics of this animal model that have contributed to its success include its genetic manipulability, invariant and fully described developmental program, well-characterized genome, ease of maintenance, short and prolific life cycle, and small body size. These same features have led to an increasing use of C. elegans in toxicology, both for mechanistic studies and high-throughput screening approaches. We describe some of the research that has been carried out in the areas of neurotoxicology, genetic toxicology, and environmental toxicology, as well as high-throughput experiments with C. elegans including genome-wide screening for molecular targets of toxicity and rapid toxicity assessment for new chemicals. We argue for an increased role for C. elegans in complementing other model systems in toxicological research

performance evaluation of knitted underwear

Institute of Textiles and Clothin