Achieving Insan Kamil Through Maqamat Tauhid Muhammad Nafis Al-Banjari andits Relevance to Modern Life

Insan kamil is an urgent concept to be understood and imitated for humans who want to achieve human perfection and even make it a way of life. However, there are various paradigms that differ in understanding and achieving the degree of insan kamil itself. This study aims to explain a method or method in achieving the degree of insan kamil through the maqamat of monotheism of Muhammad Nafis al-Banjari, which is contained in the book of ad-Durrun Nafis. This study uses a qualitative model with the type of literature study research with content analysis methods. The results of this study indicate that people who have undergone maqamat-maqamat tauhid will arrive at fanna fillah and baqa fillah where, when a servant has achieved it, will be classified as a perfect human being. This study concludes that the concept of insan kamil is very important to understand, because in reaching the insan kamil a salik will go through the stations of monotheism where the fruit of doing this will be able to see the essence of all events in this universe to avoid actions. the bad one

Changing survival, memory cell compartment, and T-helper balance of lymphocytes between severe and mild asthma

<p>Abstract</p> <p>Background</p> <p>Asthma is a complicated network of inflammatory reactions. It is classified into mild, moderate, and severe persistent asthma. The success of asthma therapy relies much on understanding the underlying mechanisms of inflammation at each stage of asthma severity. The aim of this study was to explore the differences in apoptotic potential, CD4/CD8 ratio, memory compartment, and T- helper (Th) 1 and 2 profile of peripheral blood lymphocytes (PBL) in patients with mild intermittent asthma and severe persistent asthma during exacerbation periods.</p> <p>Results</p> <p>Four research lines were investigated and compared among mild asthmatics, severe asthmatics, and healthy groups by applying immunocytochemical staining of PBL. Antiapoptotic and proapoptotic proteins with Bcl-2/Bax ratio, CD4, CD8 markers with CD4⁺/CD8⁺ratio, CD45RO⁺, CD45RA⁺markers with memory/naïve ratio (CD45RO⁺/CD45RA⁺). Th2/Th1 cytokines balance represented by IL-4/IFN-γ ratio was measured by enzyme-linked immunosorbent assay (ELISA) for in vitro PBL cytokine synthesis. It was found that Bcl-2/Bax ratio was higher in severe than in mild asthmatics which in turn was higher than in healthy group. And memory/naïve ratio of PBL was higher in severe than in mild asthmatics. Moreover, memory cells, CD45RO⁺and CD45RO⁺/CD45RA⁺ratio were correlated directly with Bcl-2/Bax, in severe and mild asthma patients. In contrast, CD4⁺/CD8⁺ratio was not changed significantly among healthy group, mild and severe asthmatics. However, CD8⁺cells were correlated directly with memory cells, CD45RO⁺, in severe asthmatics only. Interestingly, the dominant profile of cytokines appeared to change from T helper 2 (Th2) in mild asthmatics to T helper 1 (Th1) in severe asthmatics where the lowest in vitro IL-4/IFN-γ ratio and highest IFN-γ were found.</p> <p>Conclusion</p> <p>It was concluded that the underlying mechanisms of inflammation might vary greatly with asthma stage of severity. Mild intermittent asthma is mainly Th2 allergen-oriented reaction during exacerbations with good level of apoptosis making the inflammation as self-limiting, while in severe persistent asthma, the inflammatory reaction mediated mainly by Th1 cytokines with progressive loss of apoptosis leading to longer exacerbations, largely expanded memory cells, CD45RO⁺, leading to persistent baseline inflammation.</p

PKM PELATIHAN SPORT MASSAGE BAGI SISWA EKSTRAKURIKULER FUTSAL SMP NEGERI 2 MAJENE PROVINSI SULAWESI BARAT

Mitra Program Kemitraan Komunitas (PKM) ini adalah SMP Negeri 2 Majene Sulawesi Barat. Masalahnya adalah: (a) Sebagian besar Siswa SMPN 2 Majene belum pernah dibekali dengan pemahaman massage dalm pertandingan. (b) Kendala cedera dalam pertandingan masih sering didapatkan para atlet. (c) Masih kurangnya kesadaran siswa bahwa salah satu faktor agar performa atlet dilapangan baik adalah pemberian massage. Metode yang digunakan adalah: ceramah, demonstrasi, diskusi, tanya jawab, dan mitra pendamping. Hasil yang dicapai adalah : (a) Pelatihan  Sport Massage bagi siswa dapat meningkatkan  pengetahuan  tentang bagaimana pentinganya massage dalam olahraga sebagai salah satu agar kita terhindar dari cedera. (b) Peningkatan pemahaman bagi peserta pelatihan Sport Massage dilakukan dengan metode ceramah disertai tanya jawab dan demonstrasi. (c) Semua peserta sangat antusias dan kooperatif dalam mengikut pelatihan ini

Smart housing adaptations register with user matching functionalities for different mobility categories for the social housing sector

Purpose The lack of a proper register to store, match and display information on the adapted property has led to a waste of resources and prolonged delays in matching the disabled and elderly people with appropriate properties. This paper presents the development of a Housing Adaptations Register with user-matching functionalities for different mobility categories. The developed system accurately captures and documents adapted home information to facilitate the automated matching of disabled/aged applicants needing an adapted home with suitable property using banding, mobility and suitability index. Design/methodology/approach A theoretical review was conducted to identify parameters and develop adaptations register construct. A survey questionnaire approach to rate the 111 parameters in the register as either moderate, desirable or essential before system development and application. The system development relied on DSS modelling to support data-driven decision-making based on the decision table method to represent property information for implementing the decision process. The system is validated through a workshop, four brainstorming sessions and three focus group exercises. Findings Development of a choice-based system that enables the housing officers or the Housing Adaptations Register coordinators to know the level of adaptation to properties and match properties quickly with the applicants based on their mobility status. The merits of the automated system include the development of a register to capture in real-time adapted home information to facilitate the automated matching of disabled/aged applicants. A “choice-based” system that can map and suggest a property that can easily be adapted and upgraded from one mobility band to the other. Practical implications The development of a housing adaptation register helps social housing landlords to have a real-time register to match, map and upgrade properties for the most vulnerable people in our society. It saves time and money for the housing associations and the local authorities through stable tenancy for adapted homes. Potentially, it will promote the independence of aged and disabled people and can reduce their dependence on social and healthcare services. Originality/value This system provides the local authorities with objective and practical tools that may be used to assess, score, prioritise and select qualified people for appropriate accommodation based on their needs and mobility status. It will provide a record of properties adapted with their features and ensure that matching and eligibility decisions are consistent and uniform

Biodiesel from batch and continuous oleic acid esterification using zeolite catalysts

The esterification of oleic acid with ethanol was studied in both batch and continuous conditions in a fixed-bed reactor over FAU-type zeolites prepared from shale rock. The addition of Co-Ni-Pt to the zeolite increased the catalyst activity over the entire reaction temperature range. Experiments confirmed that esterification follows pseudo first-order kinetics. Thermodynamic analysis and Thiele modulus calculations show that the reaction is kinetically controlled in batch conditions, while diffusional limitations occur at higher flow rates when conducted in continuous mode. The maximum oleic acid conversions were recorded as 93% for batch and 89% for continuous, which exceed those of any analogous studies

Development of Adapt-ABLE smart system – an end-to-end system for speeding up disabled housing adaptation process

Purpose The problem of long delay and waiting time in Disabled Facilities Grants (DFG) housing adaptation has been ongoing for years. This study aimed at constructing an innovative smart solution to streamline the housing adaptation process to prevent lengthy delays for disabled and elderly people. Design/methodology/approach The Adapt-ABLE approach is suggested based on a constructive research approach, where extensive theoretical development of the Adapt-ABLE concept is developed. It consists of four integrated platforms that undergo theoretical and analogical development and validations through applicable theories, a workshop, four brainstorming sessions and a focus group. Findings The proposed Adapt-ABLE approach utilises process optimisation techniques through an IT system for streamlining the process. The merits of the semi-automated system include the development of a preventive measure that allows measurement of suitability index of homes for the occupants, indicative assessment that shorten the application duration, procurement and contracting platform that utilises principles based on framework agreement and call-off contract, and a platform that standardised performance management for continuous improvement. Originality/value The Adapt-ABLE solution will cut the application journey of non-qualified applicants and suggest where help can be sought. The qualified applicants' application journey will also be shortened through an online indicative assessment regime and early online resources (means) testing. Overall, the proposed system reduces the waiting time, and timely delivery improves the applicant's quality of life by living independently. It will potentially save the NHS billions of pounds used to replace hips and residential care costs due to lengthy delays in the housing adaptations process

A Cloud-based Collaborative Ecosystem for the Automation of BIM Execution Plan (BEP)

Master Information Delivery Plan (MIDP) is a key requirement for BIM Execution Plan (BEP) that enlists all information deliverables in BIM-based project, containing information about what would be prepared, when, by who, as well as the procedures and protocols to be used. In a well-conceived BEP, the MIDP facilitates collaboration among stakeholders. However, current approaches to generating MIDP are manual, making it tedious, error-prone, and inconsistent, thereby limiting some expected benefits of BIM implementation. The purpose of the present research is to automate the MIDP and demonstrate a collaborative BIM system that overcomes the problems associated with the traditional approach. A BIM cloud-based system (named Auto-BIMApp) involving naming that automated MIDP generation is presented. A participatory action research methodology involving academia and industry stakeholders is followed to design and validate the Auto-BIMApp. A mixed-method experiment is conducted to compare the proposed automated generation of MIDP using Auto-BIMApp with the traditional practice of using spreadsheets. The quantitative results show over 500% increased work efficiency, with improved and error-free collaboration among team members through Auto-BIMApp. Moreover, the responses from the participants using Auto-BIMApp during the experiment shows positive feedback in term of ease of use and automated functionalities of the Auto-BIMApp. The replacement of traditional practices to a complete automated collaborative system for the generation of MIDP, with substantial productivity improvement, brings novelty to the present research. The Auto-BIMApp involve multidimensional information, multiple platforms, multiple types, and levels of users, and generates three different representations of MIDP

Development of a smart home suitability indicator and indicative self-assessment platform for the disabled facilities grants (DFGs)

Purpose: Delay in housing adaptation is a major problem, especially in assessing if homes are suitable for the occupants and in determining if the occupants are qualified for the Disabled Facilities Grant (DFG). This paper describes the development of two self-administered intelligent integrated assessment tools from the DFG Adapt-ABLE system: (1) The Home Suitability Assessment Platform, which is a preventive mechanism that allows assessment of the suitability of homes based on occupants’ mobility status and (2) an indicative assessment platform that determines if the applicants are qualified for the DFG to prevent lengthy delays. Design/methodology/approach: The adopted method aligned with a development study approach: a grounded literature review, a severity measurement approach, two stakeholder engagement workshops, four brainstorming sessions and four focus group exercises. The system development relied on Entity–Relationship Diagram (ERD) technique for data structures and database systems design. It uses DFG context sensitivity with alignment with DFG guidance, interlinkages and interoperability between the assessment tools and other platforms of the integrated Adapt-ABLE system. Findings: The assessment tools are client-level outcomes related to accessibility, usability and activity based on the assessment process. The home suitability platform shows the percentage of the suitability of a home with assessment results that suggest appropriate action plans based on individual mobility status. The indicative assessment combines the function of referral, allocation, assessment and test of resources into an integrated platform. This enables timely assessment, decision-making and case-escalation by Occupational Therapists based on needs criteria and the eligibility threshold. Originality/value: These assessment tools are useful for understanding occupants’ perception of their physical housing environment in terms of accessibility, suitability and usability based on basic activities of daily living and their mobility status. The indicative self-assessment tool will substantially cut down the application journey. The developed tools have been recommended for use in the CSJ Disability Commission report and the UK government Guidance on DFGs for local authorities in England

A hybrid Artistic Model Using Deepy-Dream Model and Multiple Convolutional Neural Networks Architectures

The significant increase in drug abuse cases prompts developers to investigate techniques that mimic the hallucinations imagined by addicts and abusers, in addition to the increasing demand for the use of decorative images resulting from the use of computer technologies. This research uses Deep Dream and Neural Style Transfer technologies to solve this problem. Despite the significance researches on Deep Dream technology, there are several limitations in existing studies, including image quality and evaluation metrics. We have successfully addressed these issues by improving image quality and diversifying the types of generated images. This enhancement allows for more effective use of Deep Dream in simulating hallucinated images. Moreover, the high-quality generated images can be saved for dataset enlargement, like the augmentation process. Our proposed deepy-dream model combines features from five convolutional neural network architectures: VGG16, VGG19, Inception v3, Inception-ResNet-v2, and Xception. Additionally, we generate Deep Dream images by implementing each architecture as a separate Deep Dream model. We have employed autoencoder Deep Dream model as another method. To evaluate the performance of our models, we utilize normalized cross-correlation and structural similarity indexes as metrics. The values obtained for those two quality measures for our proposed deepy-dream model are 0.1863 and 0.0856, respectively, indicating effective performance. When considering the content image, the metrics yield values of 0.8119 and 0.3097, respectively. Whiefor the style image, the corresponding quality measure values are 0.0007 and 0.0073, respectively

Ultrasensitive, rapid and inexpensive detection of DNA using paper based lateral flow assay

Sensitive, specific, rapid, inexpensive and easy-to-use nucleic acid tests for use at the point-of-need are critical for the emerging field of personalised medicine for which companion diagnostics are essential, as well as for application in low resource settings. Here we report on the development of a point-of-care nucleic acid lateral flow test for the direct detection of isothermally amplified DNA. The recombinase polymerase amplification method is modified slightly to use tailed primers, resulting in an amplicon with a duplex flanked by two single stranded DNA tails. This tailed amplicon facilitates detection via hybridisation to a surface immobilised oligonucleotide capture probe and a gold nanoparticle labelled reporter probe. A detection limit of 1 7 10−11 M (190 amol), equivalent to 8.67 7 105 copies of DNA was achieved, with the entire assay, both amplification and detection, being completed in less than 15 minutes at a constant temperature of 37 \ub0C. The use of the tailed primers obviates the need for hapten labelling and consequent use of capture and reporter antibodies, whilst also avoiding the need for any post-amplification processing for the generation of single stranded DNA, thus presenting an assay that can facilely find application at the point of need